PDB 2uzl

PDB Information

PDB2UZL
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping.
Richardson, C.M., Nunns, C.L., Williamson, D.S., Parratt, M.J., Dokurno, P., Howes, R., Borgognoni, J., Drysdale, M.J., Finch, H., Hubbard, R.E., Jackson, P.S., Kierstan, P., Lentzen, G., Moore, J.D., Murray, J.B., Simmonite, H., Surgenor, A.E., Torrance, C.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-04-30
Resolution2.400
CATH Insert Date28 Jun, 2007

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Jun, 2007 Chopped
B 28 Jun, 2007 Chopped
C 28 Jun, 2007 Chopped
D 28 Jun, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2uzlA01 23 Jul, 2007 3.30.200.20 Assigned
2uzlA02 23 Jul, 2007 1.10.510.10 Assigned
2uzlB01 16 Jul, 2007 1.10.472.10 Assigned
2uzlB02 16 Jul, 2007 1.10.472.10 Assigned
2uzlC01 23 Jul, 2007 3.30.200.20 Assigned
2uzlC02 23 Jul, 2007 1.10.510.10 Assigned
2uzlD01 16 Jul, 2007 1.10.472.10 Assigned
2uzlD02 16 Jul, 2007 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2