PDB 2uze

PDB Information

PDB2UZE
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping.
Richardson, C.M., Nunns, C.L., Williamson, D.S., Parratt, M.J., Dokurno, P., Howes, R., Borgognoni, J., Drysdale, M.J., Finch, H., Hubbard, R.E., Jackson, P.S., Kierstan, P., Lentzen, G., Moore, J.D., Murray, J.B., Simmonite, H., Surgenor, A.E., Torrance, C.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-04-27
Resolution2.400
CATH Insert Date28 Jun, 2007

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Jun, 2007 Chopped
B 28 Jun, 2007 Chopped
C 28 Jun, 2007 Chopped
D 28 Jun, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2uzeA01 23 Jul, 2007 3.30.200.20 Assigned
2uzeA02 23 Jul, 2007 1.10.510.10 Assigned
2uzeB01 16 Jul, 2007 1.10.472.10 Assigned
2uzeB02 16 Jul, 2007 1.10.472.10 Assigned
2uzeC01 22 Jul, 2007 3.30.200.20 Assigned
2uzeC02 22 Jul, 2007 1.10.510.10 Assigned
2uzeD01 15 Jul, 2007 1.10.472.10 Assigned
2uzeD02 15 Jul, 2007 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2