PDB Information

PDB2IN6
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.
Smaill, J.B., Baker, E.N., Booth, R.J., Bridges, A.J., Dickson, J.M., Dobrusin, E.M., Ivanovic, I., Kraker, A.J., Lee, H.H., Lunney, E.A., Ortwine, D.F., Palmer, B.D., Quin, J., Squire, C.J., Thompson, A.M., Denny, W.A.
Eur.J.Med.Chem.
HeaderTransferase
Released2006-10-05
Resolution1.900
CATH Insert Date07 Nov, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2in6A01 10 Sep, 2008 3.30.200.20 Assigned
2in6A02 10 Sep, 2008 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P30291 WEE1_HUMAN Homo sapiens Wee1-like protein kinase