Discovery of S-[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]-methanone (RO3201195), and Orally Bioavailable and Highly Selective Inhibitor of p38 Map Kinase
Goldstein, D.M., Alfredson, T.A., Bertrand, J., Browner, M.F., Clifford, K., Dalrymple, S., Dunn, J., Freire-Moare, J., Harris, S.F., Labadie, S.S., La Fargue, J., Lapierre, J.M., Larrabee, S., Li, F., Papp, E., McWeeney, D., Ramesha, C., Roberts, R., Rotstein, D., San Pablo, B., Sjogren, E., So, O.Y., Talamas, F.X., Tao, W., Trejo, A., Villasenor, A., Welch, M., Welch, T., Weller, P., Whiteley, P.E., Young, K., Zipfel, S.
J.Med.Chem.