PDB 2g94

PDB Information

PDB2G94
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors.
Ghosh, A.K., Kumaragurubaran, N., Hong, L., Lei, H., Hussain, K.A., Liu, C.F., Devasamudram, T., Weerasena, V., Turner, R., Koelsch, G., Bilcer, G., Tang, J.
J.Am.Chem.Soc.
HeaderHydrolase
Released2006-03-05
Resolution1.860
CATH Insert Date14 Jul, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped
C 14 Jul, 2006 Chopped
D 14 Jul, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2g94A01 16 Oct, 2006 2.40.70.10 Assigned
2g94A02 16 Oct, 2006 2.40.70.10 Assigned
2g94B01 16 Oct, 2006 2.40.70.10 Assigned
2g94B02 16 Oct, 2006 2.40.70.10 Assigned
2g94C01 16 Oct, 2006 2.40.70.10 Assigned
2g94C02 16 Oct, 2006 2.40.70.10 Assigned
2g94D01 16 Oct, 2006 2.40.70.10 Assigned
2g94D02 16 Oct, 2006 2.40.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1