PDB Information

PDB1WPL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein
Maita, N., Hatakeyama, K., Okada, K., Hakoshima, T.
J.Biol.Chem.
HeaderHydrolase/Protein Binding
Released2004-09-08
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (51)

PDB Prints

PDB Chains (20)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Chopped
F 05 Mar, 2006 Chopped
G 05 Mar, 2006 Chopped
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Chopped
J 05 Mar, 2006 Chopped
K 05 Mar, 2006 Chopped
L 05 Mar, 2006 Chopped
M 05 Mar, 2006 Chopped
N 05 Mar, 2006 Chopped
O 05 Mar, 2006 Chopped
P 05 Mar, 2006 Chopped
Q 05 Mar, 2006 Chopped
R 05 Mar, 2006 Chopped
S 05 Mar, 2006 Chopped
T 05 Mar, 2006 Chopped

CATH Domains (30)

Domain ID Date inserted into CATH Superfamily CATH Status
1wplA01 05 Mar, 2006 1.10.286.10 Assigned
1wplA02 05 Mar, 2006 3.30.1130.10 Assigned
1wplB01 05 Mar, 2006 1.10.286.10 Assigned
1wplB02 05 Mar, 2006 3.30.1130.10 Assigned
1wplC01 05 Mar, 2006 1.10.286.10 Assigned
1wplC02 05 Mar, 2006 3.30.1130.10 Assigned
1wplD01 05 Mar, 2006 1.10.286.10 Assigned
1wplD02 05 Mar, 2006 3.30.1130.10 Assigned
1wplE01 05 Mar, 2006 1.10.286.10 Assigned
1wplE02 05 Mar, 2006 3.30.1130.10 Assigned
1wplF01 05 Mar, 2006 1.10.286.10 Assigned
1wplF02 05 Mar, 2006 3.30.1130.10 Assigned
1wplG01 05 Mar, 2006 1.10.286.10 Assigned
1wplG02 05 Mar, 2006 3.30.1130.10 Assigned
1wplH01 05 Mar, 2006 1.10.286.10 Assigned
1wplH02 05 Mar, 2006 3.30.1130.10 Assigned
1wplI01 05 Mar, 2006 1.10.286.10 Assigned
1wplI02 05 Mar, 2006 3.30.1130.10 Assigned
1wplJ01 05 Mar, 2006 1.10.286.10 Assigned
1wplJ02 05 Mar, 2006 3.30.1130.10 Assigned
1wplK00 05 Mar, 2006 3.30.1410.10 Assigned
1wplL00 05 Mar, 2006 3.30.1410.10 Assigned
1wplM00 05 Mar, 2006 3.30.1410.10 Assigned
1wplN00 05 Mar, 2006 3.30.1410.10 Assigned
1wplO00 05 Mar, 2006 3.30.1410.10 Assigned
1wplP00 05 Mar, 2006 3.30.1410.10 Assigned
1wplQ00 05 Mar, 2006 3.30.1410.10 Assigned
1wplR00 05 Mar, 2006 3.30.1410.10 Assigned
1wplS00 05 Mar, 2006 3.30.1410.10 Assigned
1wplT00 05 Mar, 2006 3.30.1410.10 Assigned

UniProtKB Entries (20)

Accession Gene ID Taxon Description
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P22288 GCH1_RAT Rattus norvegicus GTP cyclohydrolase 1
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein
P70552 GFRP_RAT Rattus norvegicus GTP cyclohydrolase 1 feedback regulatory protein