PDB 1s64
PDB Information
| PDB | 1S64 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Rattus norvegicus |
| Primary Citation | Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes.
Biochemistry
|
| Header | Transferase |
| Released | 2004-01-22 |
| Resolution | 2.550 |
| CATH Insert Date | 05 Mar, 2006 |
PDB Images (25)
1s64
PDB 1s64
1s64A
PDB Chain 1s64A
1s64B
PDB Chain 1s64B
1s64C
PDB Chain 1s64C
1s64D
PDB Chain 1s64D
1s64E
PDB Chain 1s64E
1s64F
PDB Chain 1s64F
1s64G
PDB Chain 1s64G
1s64H
PDB Chain 1s64H
1s64I
PDB Chain 1s64I
1s64J
PDB Chain 1s64J
1s64K
PDB Chain 1s64K
1s64L
PDB Chain 1s64L
1s64A00
CATH Domain 1s64A00
1s64B00
CATH Domain 1s64B00
1s64C00
CATH Domain 1s64C00
1s64D00
CATH Domain 1s64D00
1s64E00
CATH Domain 1s64E00
1s64F00
CATH Domain 1s64F00
1s64G00
CATH Domain 1s64G00
1s64H00
CATH Domain 1s64H00
1s64I00
CATH Domain 1s64I00
1s64J00
CATH Domain 1s64J00
1s64K00
CATH Domain 1s64K00
1s64L00
CATH Domain 1s64L00
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Mar, 2006 | Chopped |
| B | 05 Mar, 2006 | Chopped |
| C | 05 Mar, 2006 | Chopped |
| D | 05 Mar, 2006 | Chopped |
| E | 05 Mar, 2006 | Chopped |
| F | 05 Mar, 2006 | Chopped |
| G | 05 Mar, 2006 | Chopped |
| H | 05 Mar, 2006 | Chopped |
| I | 05 Mar, 2006 | Chopped |
| J | 05 Mar, 2006 | Chopped |
| K | 05 Mar, 2006 | Chopped |
| L | 05 Mar, 2006 | Chopped |
CATH Domains (12)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 1s64A00 | 05 Mar, 2006 | 1.25.40.120 | Assigned |
| 1s64B00 | 05 Mar, 2006 | 1.50.10.20 | Assigned |
| 1s64C00 | 05 Mar, 2006 | 1.25.40.120 | Assigned |
| 1s64D00 | 05 Mar, 2006 | 1.50.10.20 | Assigned |
| 1s64E00 | 05 Mar, 2006 | 1.25.40.120 | Assigned |
| 1s64F00 | 05 Mar, 2006 | 1.50.10.20 | Assigned |
| 1s64G00 | 05 Mar, 2006 | 1.25.40.120 | Assigned |
| 1s64H00 | 05 Mar, 2006 | 1.50.10.20 | Assigned |
| 1s64I00 | 05 Mar, 2006 | 1.25.40.120 | Assigned |
| 1s64J00 | 05 Mar, 2006 | 1.50.10.20 | Assigned |
| 1s64K00 | 05 Mar, 2006 | 1.25.40.120 | Assigned |
| 1s64L00 | 05 Mar, 2006 | 1.50.10.20 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q04631 | FNTA_RAT | Rattus norvegicus | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Q04631 | FNTA_RAT | Rattus norvegicus | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Q04631 | FNTA_RAT | Rattus norvegicus | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Q04631 | FNTA_RAT | Rattus norvegicus | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| P53610 | PGTB1_RAT | Rattus norvegicus | Geranylgeranyl transferase type-1 subunit beta |
| P53610 | PGTB1_RAT | Rattus norvegicus | Geranylgeranyl transferase type-1 subunit beta |
| Q04631 | FNTA_RAT | Rattus norvegicus | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Q04631 | FNTA_RAT | Rattus norvegicus | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| P53610 | PGTB1_RAT | Rattus norvegicus | Geranylgeranyl transferase type-1 subunit beta |
| P53610 | PGTB1_RAT | Rattus norvegicus | Geranylgeranyl transferase type-1 subunit beta |
| P53610 | PGTB1_RAT | Rattus norvegicus | Geranylgeranyl transferase type-1 subunit beta |
| P53610 | PGTB1_RAT | Rattus norvegicus | Geranylgeranyl transferase type-1 subunit beta |