PDB Information

PDB1R4M
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Walden, H., Podgorski, M.S., Huang, D.T., Miller, D.W., Howard, R.J., Minor, D.L., Holton, J.M., Schulman, B.A.
Mol.Cell
HeaderCell Cycle
Released2003-10-07
Resolution3.000
CATH Insert Date05 Mar, 2006

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Chopped
F 05 Mar, 2006 Chopped
G 05 Mar, 2006 Chopped
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Chopped
J 05 Mar, 2006 Chopped
K 05 Mar, 2006 Chopped
L 05 Mar, 2006 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
1r4mA01 18 Aug, 2007 3.40.50.720 Assigned
1r4mA02 18 Aug, 2007 Holding pen
1r4mB01 09 Mar, 2006 3.40.50.720 Assigned
1r4mB02 09 Mar, 2006 1.10.10.520 Assigned
1r4mB03 09 Mar, 2006 3.10.20.260 Assigned
1r4mC01 18 Aug, 2007 3.40.50.720 Assigned
1r4mC02 18 Aug, 2007 Holding pen
1r4mD01 09 Mar, 2006 3.40.50.720 Assigned
1r4mD02 09 Mar, 2006 1.10.10.520 Assigned
1r4mD03 09 Mar, 2006 3.10.20.260 Assigned
1r4mE01 18 Aug, 2007 3.40.50.720 Assigned
1r4mE02 18 Aug, 2007 Holding pen
1r4mF01 09 Mar, 2006 3.40.50.720 Assigned
1r4mF02 09 Mar, 2006 1.10.10.520 Assigned
1r4mF03 09 Mar, 2006 3.10.20.260 Assigned
1r4mG01 18 Aug, 2007 3.40.50.720 Assigned
1r4mG02 18 Aug, 2007 Holding pen
1r4mH01 09 Mar, 2006 3.40.50.720 Assigned
1r4mH02 09 Mar, 2006 1.10.10.520 Assigned
1r4mH03 09 Mar, 2006 3.10.20.260 Assigned
1r4mI00 05 Mar, 2006 3.10.20.90 Assigned
1r4mJ00 05 Mar, 2006 3.10.20.90 Assigned
1r4mK00 05 Mar, 2006 3.10.20.90 Assigned
1r4mL00 05 Mar, 2006 3.10.20.90 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q8TBC4 UBA3_HUMAN Homo sapiens NEDD8-activating enzyme E1 catalytic subunit
Q13564 ULA1_HUMAN Homo sapiens NEDD8-activating enzyme E1 regulatory subunit
Q13564 ULA1_HUMAN Homo sapiens NEDD8-activating enzyme E1 regulatory subunit
Q8TBC4 UBA3_HUMAN Homo sapiens NEDD8-activating enzyme E1 catalytic subunit
Q8TBC4 UBA3_HUMAN Homo sapiens NEDD8-activating enzyme E1 catalytic subunit
Q13564 ULA1_HUMAN Homo sapiens NEDD8-activating enzyme E1 regulatory subunit
Q13564 ULA1_HUMAN Homo sapiens NEDD8-activating enzyme E1 regulatory subunit
Q15843 NEDD8_HUMAN Homo sapiens NEDD8
Q15843 NEDD8_HUMAN Homo sapiens NEDD8
Q15843 NEDD8_HUMAN Homo sapiens NEDD8
Q8TBC4 UBA3_HUMAN Homo sapiens NEDD8-activating enzyme E1 catalytic subunit
Q15843 NEDD8_HUMAN Homo sapiens NEDD8