PDB Information

PDB1O5M
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Tricyclic Farnesyl Protein Transferase Inhibitors: Crystallographic and Calorimetric Studies of Structure-Activity Relationships
Strickland, C.L., Weber, P.C., Windsor, W.T., Wu, Z., Le, H.V., Albanese, M.M., Alvarez, C.S., Cesarz, D., del Rosario, J., Deskus, J., Mallams, A.K., Njoroge, F.G., Piwinski, J.J., Remiszewski, S., Rossman, R.R., Taveras, A.G., Vibulbhan, B., Doll, R.J., Girijavallabhan, V.M., Ganguly, A.K.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2003-09-26
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1o5mA00 05 Mar, 2006 1.25.40.120 Assigned
1o5mB00 05 Mar, 2006 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q02293 FNTB_RAT Rattus norvegicus Protein farnesyltransferase subunit beta
Q04631 FNTA_RAT Rattus norvegicus Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha