PDB Information

PDB1BOZ
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents.
Gangjee, A., Vidwans, A.P., Vasudevan, A., Queener, S.F., Kisliuk, R.L., Cody, V., Li, R., Galitsky, N., Luft, J.R., Pangborn, W.
J.Med.Chem.
HeaderOxidoreductase
Released1998-08-06
Resolution2.100
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1bozA00 05 Mar, 2006 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase