PDB Information

PDB1AVZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHuman immunodeficiency virus 1
Primary Citation
The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Arold, S., Franken, P., Strub, M.P., Hoh, F., Benichou, S., Benarous, R., Dumas, C.
Structure
HeaderComplex (Myristylation/Transferase)
Released1997-09-23
Resolution3.000
CATH Insert Date05 Mar, 2006

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
1avzA00 05 Mar, 2006 3.30.62.10 Assigned
1avzB00 05 Mar, 2006 3.30.62.10 Assigned
1avzC00 05 Mar, 2006 2.30.30.40 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P03406 NEF_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Protein Nef
P06241 FYN_HUMAN Homo sapiens Tyrosine-protein kinase Fyn
P03406 NEF_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Protein Nef