CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.210 | PvuII Endonuclease; Chain A |
|
3.40.210.30 | Dam replacing family, catalytic PD-(D/E)XK domain |
Domain Context
CATH Clusters
| Superfamily | Dam replacing family, catalytic PD-(D/E)XK domain |
| Functional Family |
Enzyme Information
| 3.1.21.4 |
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P0A460
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
| P0A460 |
T2D1_STRR6
Streptococcus pneumoniae R6
Type-2 restriction enzyme DpnI
|
PDB Structure
| PDB | 4ESJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Nucleic Acids Res.
|