CATH Domain: 3f61A01 XML data for domain: 3f61A01

Molscript image for 3f61A01
3f61A01
PDB coordinates for domain 3f61A01

PDB 3f61, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.200 Phosphorylase Kinase; domain 1
3.30.200.20 Phosphorylase Kinase; domain 1 Gene3D
3.30.200.20.20
3.30.200.20.20.1
3.30.200.20.20.1.1
3.30.200.20.20.1.1.1
3.30.200.20.20.1.1.1.1

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Segment boundaries for domain 3f61A01

Chopping figure for domain 3f61A01
DomainStart PDB ResidueStop PDB Residue
3f61A01 1 94
3f61A02 96 285

Structural Neighbourhood (37 entries)

There are 37 matching structural neighberhood comparisons for CATH ID 3.30.200.20.20.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 37 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3d5vA01 86.13 Danio rerioPolo-like kinase 3.30.200.20 92 21 88 2.54 2.88
3f3zA01 85.75 Cryptosporidium parvum Iowa IICalcium-dependent protein kinase [EC:2.7.11.1]Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands 3.30.200.20 81 28 86 2.76 3.18
1tkiA01 85.50 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 3.30.200.20 84 16 87 3.01 3.42
2zv2A01 85.35 Calcium ion bindingRegulation of protein kinase activityPositive regulation of transcriptionMAPKKK cascadeCytoplasm 3.30.200.20 77 23 82 2.53 3.07
1zy4A01 85.24 Eukaryotic translation initiation factor 2alpha kinase activityProtein bindingSerine/threonine-protein kinase GCN2DNA damage checkpointRegulation of translational initiation 3.30.200.20 94 23 90 3.13 3.46
3hmmA01 85.03 Type II transforming growth factor beta receptor bindingPeptidyl-threonine phosphorylationPositive regulation of cellular component movementPathway-restricted SMAD protein phosphorylationResponse to cholesterol 3.30.200.20 84 17 85 2.21 2.58
3fpqA01 84.93 Rattus norvegicusSerine/threonine-protein kinase WNK1Protein bindingPotassium channel inhibitor activityATP binding 3.30.200.20 91 24 93 3.89 4.16
2h6dA01 84.88 Insulin signaling pathwayHypertrophic cardiomyopathy (HCM)Adipocytokine signaling pathwayRegulation of autophagyMTOR signaling pathway 3.30.200.20 86 26 91 3.21 3.52
2jamA01 84.87 Calcium/calmodulin-dependent protein kinase type 1GHomo sapiensCalcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] 3.30.200.20 75 25 80 2.67 3.33
3c0iA01 84.60 Actin cytoskeletonGuanylate kinase activityPeripheral plasma membrane protein CASKCell adhesionHomo sapiens 3.30.200.20 88 27 91 3.36 3.68
2r3iA01 84.58 Progesterone-mediated oocyte maturationPathways in cancerSmall cell lung cancerOocyte meiosisProstate cancer 3.30.200.20 76 26 73 2.10 2.85
2i6lA01 84.56 Protein phosphorylationMitogen-activated protein kinase 6Homo sapiensSignal transductionMitogen-activated protein kinase 4/6 [EC:2.7.11.24] 3.30.200.20 91 23 86 3.94 4.54
2acxA02 84.29 G protein-coupled receptor kinase 6Homo sapiensRegulation of G-protein coupled receptor protein signaling pathway 3.30.200.20 91 15 90 4.06 4.51
1xbbA01 84.25 T cell receptor complexTyrosine-protein kinase SYKOrgan morphogenesisLeukocyte cell-cell adhesionCell proliferation 3.30.200.20 83 24 82 4.02 4.88
2wtkC01 84.09 NucleusSerine/threonine-protein kinase 11Cell cycle arrestProtein bindingSerine/threonine-protein kinase 11 [EC:2.7.11.9] 3.30.200.20 89 20 84 2.96 3.50
2wtjA01 83.79 DNA damage response, signal transduction resulting in induction of apoptosisSenescenceSerine/threonine-protein kinase Chk2PML bodyProtein binding 3.30.200.20 79 30 83 3.11 3.72
2rkuA01 83.61 Polo-like kinase 1 [EC:2.7.11.21]Polo kinase kinase activityProgesterone-mediated oocyte maturationCell proliferationOocyte meiosis 3.30.200.20 89 19 87 3.31 3.77
3fhrA01 83.36 Response to stressMAP kinase kinase activityNucleusMitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]MAPK signaling pathway 3.30.200.20 80 25 84 2.79 3.30
1q5kA01 83.07 Hedgehog signaling pathwayNeurotrophin signaling pathwayAlzheimer's diseaseT cell receptor signaling pathwayER overload response 3.30.200.20 95 18 86 3.84 4.45
1x8bA01 83.03 Homo sapiensWee1-like protein kinaseProtein binding 3.30.200.20 84 14 85 3.78 4.41
1ob3A01 82.93 Cyclin-dependent kinase [EC:2.7.11.22]Cell division control protein 2 homologPlasmodium falciparum K1 3.30.200.20 83 21 85 3.14 3.66
2ac3A01 82.91 MAP kinase-interacting serine/threonine-protein kinase 2ATP bindingProtein phosphorylationHomo sapiensProtein serine/threonine kinase activity 3.30.200.20 80 21 83 2.30 2.75
2clqA01 82.86 Induction of apoptosis by extracellular signalsProtein homodimerization activityMitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]Neurotrophin signaling pathwayATP binding 3.30.200.20 85 20 80 2.47 3.08
2a19C01 82.84 Eukaryotic translation initiation factor 2alpha kinase activityProtein phosphatase type 2A regulator activityInterferon-induced, double-stranded RNA-activated protein kinaseProtein bindingNegative regulation of osteoblast proliferation 3.30.200.20 95 17 89 3.22 3.60
2vgpB01 82.82 Serine/threonine-protein kinase 12-AHistone H3-S10 phosphorylationChromosome, centromeric regionProtein bindingChromatin 3.30.200.20 89 21 90 3.52 3.91
1xwsA01 82.43 Transcription factor bindingPositive regulation of cyclin-dependent protein kinase activity involved in G1/SManganese ion bindingNegative regulation of apoptosisProtein binding 3.30.200.20 92 18 80 2.75 3.42
2w5aA01 82.01 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1]Regulation of mitosisSerine/threonine-protein kinase Nek2CentrosomeCentrosome separation 3.30.200.20 64 23 68 2.51 3.68
2b9hA01 81.36 MAPK signaling pathway - yeastMating projection tipMitogen-activated protein kinase FUS3Invasive growth in response to glucose limitationNegative regulation of MAPKKK cascade 3.30.200.20 110 20 81 3.83 4.68
1omwA03 80.83 MembraneG-protein coupled receptor kinase activityNegative regulation of the force of heart contraction by chemical signalChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 3.30.200.20 107 15 74 2.95 3.95
2qkwB01 80.76 Solanum pimpinellifoliumProtein kinaseProtein binding 3.30.200.20 72 19 74 2.39 3.20
1o6lA02 80.62 Jak-STAT signaling pathwayRAC-beta serine/threonine-protein kinaseNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.30.200.20 117 18 69 3.41 4.93
2b1pA01 80.00 MAP kinase kinase activityMitogen-activated protein kinase 10Homo sapiensProtein binding 3.30.200.20 101 20 86 4.22 4.90
2jiiA01 78.15 Serine/threonine-protein kinase VRK3Homo sapiensProtein binding 3.30.200.20 110 16 70 2.50 3.53
1ckiA01 78.03 SpindleRattus norvegicusHedgehog signaling pathwaySoluble fractionCircadian rhythm - mammal 3.30.200.20 64 18 65 2.30 3.49
2jedB01 77.72 Protein kinase C theta typeProtein bindingT cell receptor signaling pathwayNovel protein kinase C [EC:2.7.11.13]Adipocytokine signaling pathway 3.30.200.20 125 21 65 3.09 4.71
3dzoA02 77.02 Toxoplasma gondiiRop2 protein 3.30.200.20 118 9 70 3.41 4.85
2oo8X01 75.15 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 3.30.200.20 60 21 60 2.61 4.32
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Displaying entries 1 to 37 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|3f61A01
MTTPSHLSDRYELGEILGFGGMSEVHLARDLRDHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEA
ETPAGPLPYIVMEY
BLAST against CATH

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Domain COMBS Sequence 

>pdb|3f61A01
GSHMTTPSHLSDRYELGEILGFGGMSEVHLARDLRDHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDT
GEAETPAGPLPYIVMEY
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 15 Dec 2008 20:39

Assigning to "3.30.200.20" based on similarity with "1mruA01"

Flow stage update by auto on 15 Dec 2008 20:17

No in_process hits for Domain "3f61A01" ready to be processed

Flow stage update by auto on 15 Dec 2008 20:17

NW result present for Domain "3f61A01"

Flow stage update by auto on 10 Dec 2008 14:17

All required files are present for Domain "3f61A01"

Flow stage update by auto on 10 Dec 2008 14:15

Beginning processing for Domain "3f61A01"

Insertion by auto on 08 Dec 2008 11:09

Final ChopClose added based on similarity with "1mruA"