CATH Domain: 3dfjA02 XML data for domain: 3dfjA02

Molscript image for 3dfjA02
3dfjA02
PDB coordinates for domain 3dfjA02

PDB 3dfj, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.11
2.40.10.10.11.1
2.40.10.10.11.1.2
2.40.10.10.11.1.2.1
2.40.10.10.11.1.2.1.1

[top]
Segment boundaries for domain 3dfjA02

Chopping figure for domain 3dfjA02
DomainStart PDB ResidueStop PDB Residue
3dfjA01 45 56
3dfjA01 153 275
3dfjA02 57 152
3dfjA02 276 292

Structural Neighbourhood (35 entries)

There are 35 matching structural neighberhood comparisons for CATH ID 2.40.10.10.11.1.2.1.1 (SIMAX score < 5)

[1]
Displaying entries 1 to 35 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1bioA02 92.12 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 40 94 1.55 1.64
2anyA02 92.02 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 35 96 2.14 2.22
1eaxA02 91.78 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 115 35 93 1.56 1.68
1ym0A02 91.58 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 27 95 1.25 1.31
2wphS02 91.29 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 32 94 1.69 1.79
1p57B02 91.28 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 37 92 2.19 2.37
1a7sA02 91.03 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 26 92 1.39 1.50
1nn6A02 90.94 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 25 91 1.66 1.81
1gvzA02 90.83 Equus caballusKallikrein-1E2 2.40.10.10 115 29 89 1.29 1.44
2r0lA02 90.72 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 29 92 1.58 1.70
1orfA02 90.24 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 28 92 1.68 1.81
2jkhA02 90.20 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 30 92 1.56 1.68
2aiqA02 89.73 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 28 90 2.06 2.28
1fiwA02 89.40 Ovis ariesAcrosinDrug binding 2.40.10.10 120 35 90 2.47 2.74
1gj7B02 89.32 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 36 89 1.51 1.68
2asuB02 89.18 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 33 88 1.45 1.64
2qxiA02 89.03 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 31 88 1.50 1.70
2hlcA01 88.84 CollagenaseHypoderma lineatum 2.40.10.10 104 26 90 2.92 3.24
3beuA02 88.35 Streptomyces griseusTrypsin 2.40.10.10 99 29 88 2.43 2.75
3govB02 88.09 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 25 87 2.46 2.80
1elvA01 88.05 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 26 81 1.72 2.10
1q3xA03 87.97 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 27 88 1.92 2.17
1rrkA02 87.10 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 27 76 2.55 3.35
1p3cA02 84.99 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 17 89 2.50 2.80
1agjA02 84.77 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 15 87 2.64 3.02
2pkaA00 84.00 Sus scrofaGlandular kallikrein 2.40.10.10 80 35 60 1.54 2.55
2o8lA02 83.87 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 17 78 2.91 3.71
1ky9A01 82.06 Two-component systemSerine-type endopeptidase activityProtease doResponse to temperature stimulusProtein binding 2.40.10.10 88 19 73 3.09 4.18
1sotA01 80.87 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 9 73 3.64 4.94
1lcyA01 80.57 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 11 72 2.58 3.58
2qf3A01 80.50 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 102 10 66 3.06 4.59
2z9iC01 79.16 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 91 12 66 2.51 3.77
2halA01 77.82 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 9 78 3.38 4.31
2hntC00 74.83 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 67 28 43 1.38 3.19
1eptA00 69.40 Sus scrofaTrypsin 2.40.10.10 43 44 27 0.96 3.44
[1]
Displaying entries 1 to 35 (page 1 of 1)


[top]
Domain ATOM Sequence 

>pdb|3dfjA02
PWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIA
LLQLSRPITFSRYIRPSYASWIQSKVTELQLVP
BLAST against CATH

[top]
Domain COMBS Sequence 

>pdb|3dfjA02
PWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIA
LLQLSRPITFSRYIRPSYASWIQSKVTELQLVPRGSGSGSLEHHHHHH
BLAST against CATH

[top]
Domain History Events (10)

Domain assigned by auto on 18 Oct 2008 21:03

Assigning to "2.40.10.10" based on similarity with "3e0pB02"

Flow stage update by auto on 18 Oct 2008 21:03

No in_process hits for Domain "3dfjA02" ready to be processed

Update comment by auto on 18 Oct 2008 20:49

Domain "3dfjA02" hits Domain "3dflA02" (100% over 85.9375%) which is currently in process

Update comment by auto on 18 Oct 2008 20:29

Domain "3dfjA02" hits Domain "2zdmA02" (35.2941176470588% over 79.6875%) which is currently in process

Update comment by auto on 18 Oct 2008 17:29

Domain "3dfjA02" hits Domain "2zdnA02" (35.2941176470588% over 79.6875%) which is currently in process

Flow stage update by auto on 18 Oct 2008 17:09

Domain "3dfjA02" hits Domain "2zdnA02" (35.2941176470588% over 79.6875%) which is currently in process

Flow stage update by auto on 18 Oct 2008 17:09

NW result present for Domain "3dfjA02"

Flow stage update by auto on 18 Oct 2008 11:11

All required files are present for Domain "3dfjA02"

Flow stage update by auto on 17 Oct 2008 15:08

Beginning processing for Domain "3dfjA02"

Insertion by auto on 17 Oct 2008 14:28

Final ChopClose added based on similarity with "3e0pB"