CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Carbonic anhydrase 2

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P00918
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P00918
CAH2_HUMAN
Homo sapiens
Carbonic anhydrase 2

PDB Structure

PDB 3CYU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of a 129Xe-cryptophane biosensor complexed with human carbonic anhydrase II.
Aaron, J.A., Chambers, J.M., Jude, K.M., Di Costanzo, L., Dmochowski, I.J., Christianson, D.W.
J.Am.Chem.Soc.