CATH Domain: 3bqcA02 XML data for domain: 3bqcA02

Molscript image for 3bqcA02
3bqcA02
PDB coordinates for domain 3bqcA02

PDB 3bqc, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.200 Phosphorylase Kinase; domain 1
3.30.200.20 Phosphorylase Kinase; domain 1 Gene3D
3.30.200.20.3
3.30.200.20.3.1
3.30.200.20.3.1.1
3.30.200.20.3.1.1.1
3.30.200.20.3.1.1.1.1

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Segment boundaries for domain 3bqcA02

Chopping figure for domain 3bqcA02
DomainStart PDB ResidueStop PDB Residue
3bqcA01 7 24
3bqcA01 116 330
3bqcA02 25 115

Structural Neighbourhood (59 entries)

There are 59 matching structural neighberhood comparisons for CATH ID 3.30.200.20.3.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 59 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1qpcA01 87.84 Pericentriolar materialPhosphoinositide 3-kinase bindingCD8 receptor bindingT cell receptor signaling pathwayCD4 receptor binding 3.30.200.20 88 20 90 2.11 2.34
1uu3A02 87.55 PPAR signaling pathway3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]Peptidyl-threonine phosphorylationAldosterone-regulated sodium reabsorptionNon-small cell lung cancer 3.30.200.20 93 18 89 2.88 3.23
3blhA01 87.42 Transcription elongation from RNA polymerase II promoterCyclin-dependent protein kinase activityRNA polymerase II carboxy-terminal domain kinase activityProtein bindingCell proliferation 3.30.200.20 86 27 91 3.83 4.20
1tkiA01 87.42 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 3.30.200.20 84 22 87 2.69 3.06
1u5qA01 87.38 Rattus norvegicusThousand and one amino acid protein kinase [EC:2.7.11.1]Serine/threonine-protein kinase TAO2MAPK signaling pathway 3.30.200.20 96 24 91 2.93 3.20
3k3iA01 87.17 Cellular component movementMAP kinase kinase activityProtein bindingChemotaxisMitogen-activated protein kinase 14 3.30.200.20 92 25 88 3.74 4.25
2acxA02 86.99 G protein-coupled receptor kinase 6Homo sapiensRegulation of G-protein coupled receptor protein signaling pathway 3.30.200.20 91 17 89 1.95 2.19
3eqrB01 86.75 Activated CDC42 kinase 1GTPase inhibitor activitySmall GTPase mediated signal transductionHomo sapiensPositive regulation of peptidyl-tyrosine phosphorylation 3.30.200.20 91 24 90 2.89 3.21
2wtkC01 86.74 NucleusSerine/threonine-protein kinase 11Cell cycle arrestProtein bindingSerine/threonine-protein kinase 11 [EC:2.7.11.9] 3.30.200.20 89 25 82 1.47 1.78
1xbbA01 86.69 T cell receptor complexTyrosine-protein kinase SYKOrgan morphogenesisLeukocyte cell-cell adhesionCell proliferation 3.30.200.20 83 25 87 1.91 2.17
3fhrA01 86.68 Response to stressMAP kinase kinase activityNucleusMitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]MAPK signaling pathway 3.30.200.20 80 25 85 2.08 2.43
3c0iA01 86.55 Actin cytoskeletonGuanylate kinase activityPeripheral plasma membrane protein CASKCell adhesionHomo sapiens 3.30.200.20 88 26 87 2.38 2.71
2zv2A01 86.37 Calcium ion bindingRegulation of protein kinase activityPositive regulation of transcriptionMAPKKK cascadeCytoplasm 3.30.200.20 77 29 84 3.24 3.83
2evaA01 86.37 Positive regulation of T cell cytokine productionActivation of NF-kappaB-inducing kinase activityPositive regulation of interleukin-2 productionMitogen-activated protein kinase kinase kinase 7Protein binding 3.30.200.20 82 21 86 2.40 2.76
1x8bA01 86.29 Homo sapiensWee1-like protein kinaseProtein binding 3.30.200.20 84 13 85 3.76 4.39
2j51A01 86.24 CytoplasmOocyte meiosisSTE20-like serine/threonine-protein kinasePlasma membraneHomo sapiens 3.30.200.20 90 21 92 2.23 2.42
1xwsA01 86.10 Transcription factor bindingPositive regulation of cyclin-dependent protein kinase activity involved in G1/SManganese ion bindingNegative regulation of apoptosisProtein binding 3.30.200.20 92 20 86 2.41 2.77
2jamA01 86.02 Calcium/calmodulin-dependent protein kinase type 1GHomo sapiensCalcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] 3.30.200.20 75 26 82 2.10 2.55
3e64A01 86.01 Jak-STAT signaling pathwayCellular component movementTyrosine-protein kinase JAK2Chemokine signaling pathwayAdipocytokine signaling pathway 3.30.200.20 93 21 92 4.16 4.50
2ac3A01 85.94 MAP kinase-interacting serine/threonine-protein kinase 2ATP bindingProtein phosphorylationHomo sapiensProtein serine/threonine kinase activity 3.30.200.20 80 27 83 1.81 2.17
3bceA01 85.91 Receptor tyrosine-protein kinase erbB-4Transmembrane receptor protein tyrosine kinase activityHomo sapiensBasolateral plasma membraneProtein binding 3.30.200.20 94 19 92 3.70 4.00
3hmmA01 85.88 Type II transforming growth factor beta receptor bindingPeptidyl-threonine phosphorylationPositive regulation of cellular component movementPathway-restricted SMAD protein phosphorylationResponse to cholesterol 3.30.200.20 84 20 86 2.15 2.48
3bu3A01 85.74 Insulin receptorInsulin receptor complexPositive regulation of nitric oxide biosynthetic processPhosphoinositide 3-kinase bindingPositive regulation of respiratory burst 3.30.200.20 92 16 90 2.63 2.92
1ia8A01 85.62 SenescenceReciprocal meiotic recombinationSerine/threonine-protein kinase Chk1Regulation of cyclin-dependent protein kinase activityProtein binding 3.30.200.20 93 26 87 4.12 4.73
3c4cA01 85.57 Neurotrophin signaling pathwayNon-small cell lung cancerCytoplasmErbB signaling pathwayProtein phosphorylation 3.30.200.20 86 17 86 2.77 3.19
3cc6A01 85.54 Calcium signaling pathwayChemokine signaling pathwayPositive regulation of cell proliferationProtein-tyrosine kinase 2-betaLeukocyte transendothelial migration 3.30.200.20 90 25 91 3.72 4.08
1t46A01 85.50 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Protein bindingAcute myeloid leukemia 3.30.200.20 96 20 90 2.72 3.00
3f3zA01 85.43 Cryptosporidium parvum Iowa IICalcium-dependent protein kinase [EC:2.7.11.1]Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands 3.30.200.20 81 28 85 2.04 2.38
2rkuA01 85.34 Polo-like kinase 1 [EC:2.7.11.21]Polo kinase kinase activityProgesterone-mediated oocyte maturationCell proliferationOocyte meiosis 3.30.200.20 89 20 86 2.08 2.40
2dylA01 85.32 Mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]MAP kinase kinase activityNeurotrophin signaling pathwayStress-activated MAPK cascadeT cell receptor signaling pathway 3.30.200.20 91 9 83 2.34 2.80
1fmkA03 85.32 Epithelial cell signaling in Helicobacter pylori infectionPositive regulation of integrin activationRegulation of bone resorptionProto-oncogene tyrosine-protein kinase SrcErbB signaling pathway 3.30.200.20 86 18 87 2.97 3.38
1fvrA01 85.27 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 3.30.200.20 86 19 91 3.25 3.56
2oibA01 85.01 Chagas diseaseNeurotrophin signaling pathwayInterleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]ApoptosisHomo sapiens 3.30.200.20 93 18 86 3.49 4.06
2clqA01 85.01 Induction of apoptosis by extracellular signalsProtein homodimerization activityMitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]Neurotrophin signaling pathwayATP binding 3.30.200.20 85 16 84 2.07 2.45
3f66B01 84.84 Hepatocyte growth factor receptor activityBasal plasma membranePathways in cancerEpithelial cell signaling in Helicobacter pylori infectionProto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] 3.30.200.20 85 17 91 3.25 3.56
2weiA01 84.73 Cryptosporidium parvum Iowa IICalmodulin-domain protein kinase 1, putative 3.30.200.20 90 22 91 3.38 3.71
2rgpA01 84.71 Calcium signaling pathwayPositive regulation of nitric oxide biosynthetic processEpidermal growth factor receptor activityResponse to UV-APositive regulation of cyclin-dependent protein kinase activity involved in G1/S 3.30.200.20 82 19 89 3.30 3.71
1zy4A01 84.71 Eukaryotic translation initiation factor 2alpha kinase activityProtein bindingSerine/threonine-protein kinase GCN2DNA damage checkpointRegulation of translational initiation 3.30.200.20 94 13 88 3.52 3.99
1lufA01 84.58 Muscle, skeletal receptor tyrosine protein kinaseReceptor clusteringRattus norvegicusResponse to muscle activityMemory 3.30.200.20 97 23 90 3.36 3.70
2izrA01 84.53 Casein kinase I isoform gamma-3Homo sapiensSignal transduction 3.30.200.20 83 18 89 3.81 4.28
2vgpB01 84.46 Serine/threonine-protein kinase 12-AHistone H3-S10 phosphorylationChromosome, centromeric regionProtein bindingChromatin 3.30.200.20 89 24 86 2.40 2.76
2r3iA01 84.40 Progesterone-mediated oocyte maturationPathways in cancerSmall cell lung cancerOocyte meiosisProstate cancer 3.30.200.20 76 30 79 2.79 3.53
1omwA03 84.36 MembraneG-protein coupled receptor kinase activityNegative regulation of the force of heart contraction by chemical signalChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 3.30.200.20 107 14 74 1.95 2.61
2h6dA01 84.33 Insulin signaling pathwayHypertrophic cardiomyopathy (HCM)Adipocytokine signaling pathwayRegulation of autophagyMTOR signaling pathway 3.30.200.20 86 30 87 3.64 4.14
2j0iA01 84.31 Cellular component movementT cell receptor signaling pathwaySignal transductionProtein bindingRenal cell carcinoma 3.30.200.20 98 15 89 3.55 3.95
1s9jA01 84.07 Prion diseasesNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 3.30.200.20 86 15 89 3.27 3.67
1ob3A01 84.05 Cyclin-dependent kinase [EC:2.7.11.22]Cell division control protein 2 homologPlasmodium falciparum K1 3.30.200.20 83 31 83 2.85 3.41
3g51A01 83.61 Progesterone-mediated oocyte maturationNeurotrophin signaling pathwayOocyte meiosisMAPK signaling pathwayLong-term potentiation 3.30.200.20 95 17 88 3.41 3.86
1o6lA02 83.39 Jak-STAT signaling pathwayRAC-beta serine/threonine-protein kinaseNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.30.200.20 117 17 68 1.79 2.62
2qkwB01 83.36 Solanum pimpinellifoliumProtein kinaseProtein binding 3.30.200.20 72 16 73 1.79 2.43
2w5aA01 82.97 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1]Regulation of mitosisSerine/threonine-protein kinase Nek2CentrosomeCentrosome separation 3.30.200.20 64 20 69 2.25 3.25
1rdqE02 82.63 Calcium signaling pathwayPrion diseasesProtein kinase A [EC:2.7.11.11]Olfactory transductionMesoderm formation 3.30.200.20 124 19 67 1.96 2.89
2f57B01 81.40 T cell receptor signaling pathwayP21-activated kinase 7 [EC:2.7.11.1]Protein bindingRenal cell carcinomaErbB signaling pathway 3.30.200.20 106 16 82 3.38 4.12
2jedB01 80.83 Protein kinase C theta typeProtein bindingT cell receptor signaling pathwayNovel protein kinase C [EC:2.7.11.13]Adipocytokine signaling pathway 3.30.200.20 125 19 64 1.89 2.95
1ckiA01 80.51 SpindleRattus norvegicusHedgehog signaling pathwaySoluble fractionCircadian rhythm - mammal 3.30.200.20 64 23 68 2.29 3.36
3g0eA01 79.66 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Protein bindingAcute myeloid leukemia 3.30.200.20 131 21 67 2.49 3.67
1kutB01 79.38 Thermotoga maritimaPhosphoribosylaminoimidazole-succinocarboxamide synthasePurine metabolismPhosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]Metabolic pathways 3.30.200.20 88 7 64 2.39 3.69
2oo8X01 78.75 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 3.30.200.20 60 23 61 2.24 3.64
3kreA01 78.44 Phosphoribosylaminoimidazole-succinocarboxamide synthasePurine metabolismPhosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]Ehrlichia chaffeensis str. ArkansasMetabolic pathways 3.30.200.20 94 8 64 2.77 4.27
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Displaying entries 1 to 59 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|3bqcA02
DYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDP
VSRTPALVFEH
BLAST against CATH

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Domain COMBS Sequence 

>pdb|3bqcA02
DYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDP
VSRTPALVFEH
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 20 Jan 2008 05:27

Assigning to "3.30.200.20" based on similarity with "1jwhA01"

Flow stage update by auto on 20 Jan 2008 05:06

NW result present for Domain "3bqcA02"

Flow stage update by auto on 20 Jan 2008 05:06

No in_process hits for Domain "3bqcA02" ready to be processed

Flow stage update by auto on 19 Jan 2008 11:04

All required files are present for Domain "3bqcA02"

Flow stage update by auto on 18 Jan 2008 23:22

Beginning processing for Domain "3bqcA02"

Insertion by auto on 18 Jan 2008 23:06

Final ChopClose added based on similarity with "2rkpA"