CATH Domain: 2tnfA00 XML data for domain: 2tnfA00

Molscript image for 2tnfA00
2tnfA00
PDB coordinates for domain 2tnfA00

PDB 2tnf, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.120 Jelly Rolls
2.60.120.40 Gene3D
2.60.120.40.3
2.60.120.40.3.1
2.60.120.40.3.1.1
2.60.120.40.3.1.1.1
2.60.120.40.3.1.1.1.1

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Segment boundaries for domain 2tnfA00

Chopping figure for domain 2tnfA00
DomainStart PDB ResidueStop PDB Residue
2tnfA00 9 157

Structural Neighbourhood (7 entries)

There are 7 matching structural neighberhood comparisons for CATH ID 2.60.120.40.3.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 7 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1tnrA00 90.76 Lymphotoxin-alphaType I diabetes mellitusSignal transductionLymphotoxin alpha (TNF superfamily, member 1)Induction of apoptosis 2.60.120.40 144 35 93 1.34 1.43
1s55A00 87.35 Mammary gland epithelial cell proliferationOssificationOrgan morphogenesisLymph node developmentProtein homooligomerization 2.60.120.40 156 25 89 2.36 2.63
1alyA00 87.21 Soluble fractionAutoimmune thyroid diseaseIntestinal immune network for IgA productionAllograft rejectionT cell receptor signaling pathway 2.60.120.40 146 23 93 2.25 2.41
1xu1A00 84.99 Mus musculusImmunoglobulin production in mucosal tissueExternal side of plasma membranePositive regulation of germinal center formationTumor necrosis factor ligand superfamily member 13 2.60.120.40 137 21 87 2.72 3.10
1rj8A00 84.87 Membrane fractionEctodysplasin-ACytoskeletonSignal transductionEctodysplasin-A 2.60.120.40 140 18 83 2.42 2.89
1o91A00 82.89 Mus musculusCamera-type eye morphogenesisCollagen alpha-1(VIII) chainEpithelial cell proliferationPositive regulation of cell-substrate adhesion 2.60.120.40 131 12 81 2.50 3.08
2q8oA00 81.62 Mus musculusGITR ligand 2.60.120.40 125 16 75 2.08 2.75
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Displaying entries 1 to 7 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2tnfA00
SDKPVAHVVANHQVEEQLEWLSQRANALLANGMDLKDNQLVVPADGLYLVYSQVLFKGQGCPDYVLLTHTVSRFAISYQE
KVNLLSAVKSPCPKDTPEGAELKPWYEPIYLGGVFQLEKGDQLSAEVNLPKYLDFAESGQVYFGVIAL
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2tnfA00
LRSSSQNSSDKPVAHVVANHQVEEQLEWLSQRANALLANGMDLKDNQLVVPADGLYLVYSQVLFKGQGCPDYVLLTHTVS
RFAISYQEKVNLLSAVKSPCPKDTPEGAELKPWYEPIYLGGVFQLEKGDQLSAEVNLPKYLDFAESGQVYFGVIAL
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:45

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:45

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 15:04

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"