CATH Domain: 2q20A00 XML data for domain: 2q20A00

Molscript image for 2q20A00
2q20A00
PDB coordinates for domain 2q20A00

PDB 2q20, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.6
2.60.40.10.6.1
2.60.40.10.6.1.1
2.60.40.10.6.1.1.1
2.60.40.10.6.1.1.1.1

Segment boundaries for domain 2q20A00

Chopping figure for domain 2q20A00
DomainStart PDB ResidueStop PDB Residue
2q20A00 0 107

Structural Neighbourhood (185 entries)

There are 185 matching structural neighberhood comparisons for CATH ID 2.60.40.10.6.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 185 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1x9qA01 94.17 2.60.40.10 111 54 93 0.81 0.86
1mjuL01 93.03 2.60.40.10 113 53 92 0.83 0.90
2aepL01 92.46 2.60.40.10 119 60 87 0.73 0.84
1pewA00 91.09 Ig lambda chain V-VI region SUTHomo sapiens 2.60.40.10 108 42 93 1.46 1.56
1oaqL00 90.95 2.60.40.10 110 40 94 1.95 2.06
2otuA00 89.74 2.60.40.10 115 41 90 1.63 1.80
1ogaD01 89.51 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 109 30 94 3.48 3.68
1kgcE01 89.38 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 112 28 91 1.86 2.04
2ialA01 89.01 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 108 29 91 1.84 2.01
3bp6A00 88.57 Mus musculusExternal side of plasma membraneProgrammed cell death protein 1Programmed cell death protein 1T cell receptor signaling pathway 2.60.40.10 111 22 90 1.80 2.00
2ij0C00 88.22 Homo sapiensT cell receptor beta variable 20/OR9-2 2.60.40.10 118 28 88 1.50 1.70
1u3hA00 87.98 Mus musculusTRAV14-3 2.60.40.10 110 32 89 1.78 2.00
2nw2A01 87.83 TRA@ proteinHomo sapiens 2.60.40.10 103 30 89 2.33 2.60
1ogaE01 87.74 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 111 26 90 1.97 2.17
2hp4A00 87.70 T-cell surface glycoprotein CD8 alpha chainCD8A antigen, alpha polypeptideHematopoietic cell lineagePrimary immunodeficiencyHomo sapiens 2.60.40.10 112 21 90 2.15 2.38
2q8bH01 87.67 2.60.40.10 112 22 89 1.74 1.95
2ak4D01 87.52 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 114 27 85 2.02 2.35
1mjuH01 87.32 2.60.40.10 115 23 89 1.87 2.09
2vxtH01 87.24 2.60.40.10 113 22 89 2.17 2.43
1lp9E01 87.00 2.60.40.10 113 27 87 1.82 2.08
1yc7A00 86.90 2.60.40.10 116 26 88 2.42 2.73
1tvdA00 86.82 Homo sapiensHDV103S1 2.60.40.10 116 26 88 2.01 2.26
1nezH00 86.61 T-cell surface glycoprotein CD8 alpha chainProtein homodimerization activityHematopoietic cell lineageCD8A antigen, alpha polypeptideT cell receptor signaling pathway 2.60.40.10 120 17 86 1.81 2.09
1hxmB01 86.29 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 125 27 83 1.73 2.08
1f3rB02 86.16 2.60.40.10 99 62 79 2.57 3.25
1kgcD01 86.11 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 111 25 88 2.35 2.66
1mfaH01 85.98 2.60.40.10 97 22 82 1.96 2.37
1f97A01 85.77 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 102 14 93 2.08 2.23
2v44A01 85.76 Prion diseasesNeural cell adhesion moleculeNeuron cell-cell adhesionPlasma membraneNeural cell adhesion molecule 2 2.60.40.10 94 25 87 1.96 2.24
1xauA00 85.75 Integral to plasma membraneReceptor activityNegative regulation of B cell proliferationProtein bindingMus musculus 2.60.40.10 104 15 90 2.27 2.51
1fo0B00 85.61 2.60.40.10 112 17 90 2.90 3.22
2p45B00 85.48 2.60.40.10 116 26 87 3.28 3.77
3d9aH01 85.34 2.60.40.10 112 22 91 2.23 2.45
1hxmA01 85.34 2.60.40.10 121 20 85 2.09 2.43
1t2jA00 85.30 Homo sapiensSingle chain Fv 2.60.40.10 116 24 89 2.93 3.27
2rikA01 84.74 TitinOryctolagus cuniculus 2.60.40.10 96 11 86 2.04 2.35
2rikA02 84.72 TitinOryctolagus cuniculus 2.60.40.10 95 13 85 2.20 2.57
1fhgA00 84.48 TelokinMeleagris gallopavo 2.60.40.10 102 11 86 2.11 2.43
1ncwH01 84.45 2.60.40.10 119 24 87 2.34 2.68
1neuA00 84.18 Rattus norvegicusMyelin protein P0 2.60.40.10 115 20 87 2.02 2.30
1l6zA02 84.13 Mus musculusCarcinoembryonic antigen-related cell adhesion molecule 1 2.60.40.10 96 17 84 2.24 2.64
1qfoC00 84.11 Mus musculusSialoadhesinProtein binding 2.60.40.10 114 17 89 2.73 3.05
2ny1B01 84.01 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 98 18 84 2.27 2.68
1dr9A01 83.99 Type I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA productionAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 105 14 86 2.67 3.08
2bk8A00 83.95 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 97 12 86 2.11 2.43
2a38B01 83.95 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 99 12 88 2.12 2.39
1bihA03 83.82 Hyalophora cecropiaHemolin 2.60.40.10 100 15 87 3.31 3.78
1iilG02 83.80 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 107 16 85 3.42 4.02
1g1cA00 83.79 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 98 10 86 2.28 2.63
1eajB00 83.78 Integral to plasma membraneReceptor activityCoxsackievirus and adenovirus receptorViral myocarditisCoxsackievirus and adenovirus receptor 2.60.40.10 120 15 85 2.48 2.89
1cs6A01 83.77 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 105 12 86 2.67 3.08
1f97A02 83.68 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 105 13 89 2.48 2.77
1hkfA00 83.65 Integral to plasma membraneNatural cytotoxicity triggering receptor 2Cellular defense responseNatural killer cell mediated cytotoxicitySignal transduction 2.60.40.10 108 18 92 4.36 4.71
2j8hA01 83.62 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 97 15 87 2.40 2.74
1smoB00 83.62 Receptor activityTriggering receptor expressed on myeloid cells 1Homo sapiensHumoral immune response 2.60.40.10 110 14 84 2.88 3.41
2fcbA02 83.56 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 87 10 75 2.25 2.99
3b43A02 83.48 TitinOryctolagus cuniculus 2.60.40.10 97 13 86 2.18 2.52
2g5rA00 83.44 Sialic acid-binding Ig-like lectin 7Sialic acid binding Ig-like lectin 7Receptor activityIntegral to plasma membraneHomo sapiens 2.60.40.10 113 15 88 3.17 3.58
1cs6A04 83.37 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 90 17 82 2.26 2.73
2c5dC01 83.34 Integral to plasma membraneTransmembrane receptor protein tyrosine kinase activityHomo sapiensTyrosine-protein kinase receptor UFOSignal transduction 2.60.40.10 104 14 83 2.11 2.52
1rhfA01 83.29 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 89 15 78 2.89 3.70
3cafA01 83.19 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 96 10 84 2.31 2.73
1ypzF01 83.19 2.60.40.10 123 25 84 2.92 3.45
1waaC00 83.18 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 93 11 82 2.06 2.49
2ec8A03 83.12 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 104 15 82 2.39 2.88
2q87C00 83.08 Homo sapiensCMRF35-like molecule 8CD300 antigen 2.60.40.10 106 15 90 3.77 4.16
3k3qA00 82.91 2.60.40.10 137 21 75 2.71 3.57
1qz1A03 82.88 Rattus norvegicusPrion diseasesNeural cell adhesion moleculePlasma membraneFibroblast growth factor receptor binding 2.60.40.10 95 16 84 2.67 3.15
1vcaA01 82.87 Vascular cell adhesion protein 1MicrovillusPositive regulation of T cell proliferationHeterophilic cell-cell adhesionFilopodium 2.60.40.10 89 20 81 2.25 2.75
2qsqB01 82.76 Carcinoembryonic antigen-related cell adhesion molecule 5Integral to plasma membraneHomo sapiensBasolateral plasma membrane 2.60.40.10 108 12 91 3.34 3.64
1gl4B00 82.69 Chondrocyte differentiationCardiac muscle tissue developmentCartilage development involved in endochondral bone morphogenesisProtein localizationBrain development 2.60.40.10 89 25 82 3.18 3.84
2j8hA02 82.66 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 9 84 2.26 2.67
1cczA01 82.58 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 93 12 84 2.52 2.97
2rikA03 82.54 TitinOryctolagus cuniculus 2.60.40.10 92 14 84 2.16 2.55
1koaA03 82.51 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 96 11 85 2.32 2.71
1i1rA01 82.39 Jak-STAT signaling pathwayOncostatin-M receptor complexResponse to cytokine stimulusPositive regulation of osteoblast differentiationPositive regulation of tyrosine phosphorylation of Stat1 protein 2.60.40.10 100 12 82 2.64 3.19
1bihA04 82.25 Hyalophora cecropiaHemolin 2.60.40.10 88 14 80 2.11 2.61
1olzA03 82.15 Anti-apoptosisReceptor bindingSemaphorin-4DReceptor activityCell adhesion 2.60.40.10 89 14 79 2.38 3.01
2v44A02 82.07 Prion diseasesNeural cell adhesion moleculePlasma membraneNeuron cell-cell adhesionNeural cell adhesion molecule 2 2.60.40.10 93 12 83 2.24 2.67
1nkrA01 82.05 Integral to plasma membraneReceptor activityHomo sapiensNatural killer cell inhibitory signaling pathwayImmune response 2.60.40.10 97 10 81 2.70 3.30
1cs6A03 82.04 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 98 16 82 2.50 3.02
2dm2A00 81.97 NucleusHomo sapiensPalladinActin filamentMuscle alpha-actinin binding 2.60.40.10 110 9 83 2.39 2.86
1bihA01 81.95 Hyalophora cecropiaHemolin 2.60.40.10 97 9 85 3.05 3.56
2fcbA01 81.81 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 86 12 74 2.61 3.51
1pkoA00 81.81 Rattus norvegicusMyelin-oligodendrocyte glycoproteinPositive regulation of MyD88-dependent toll-like receptor signaling pathway 2.60.40.10 123 14 81 2.22 2.73
1uctA01 81.80 Immunoglobulin alpha Fc receptorIntegral to plasma membraneCD89 antigenHomo sapiensImmune response 2.60.40.10 91 14 82 3.03 3.66
3bfoA00 81.73 T cell receptor signaling pathwayPositive regulation of T cell cytokine productionActivation of NF-kappaB-inducing kinase activityPositive regulation of interleukin-2 productionNucleus 2.60.40.10 85 16 78 2.26 2.89
1dqtA00 81.64 Mus musculusExternal side of plasma membraneCytotoxic T-lymphocyte protein 4 2.60.40.10 117 21 83 2.76 3.30
1nkrA02 81.60 Receptor activityIntegral to plasma membraneHomo sapiensImmune responseNatural killer cell inhibitory signaling pathway 2.60.40.10 98 9 83 3.44 4.10
2ec8A01 81.57 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 92 9 72 2.32 3.21
1rhfA02 81.55 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 84 9 76 2.25 2.95
1ugnA01 81.50 Homo sapiensLeukocyte immunoglobulin-like receptor subfamily B member 1Integral to membraneResponse to virusProtein phosphatase 1 binding 2.60.40.10 95 15 83 3.52 4.20
1itbB03 81.15 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 112 6 82 2.45 2.98
1gsmA01 81.12 Membrane fractionMucosal vascular addressin cell adhesion molecule 1Intestinal immune network for IgA productionCell adhesionHomo sapiens 2.60.40.10 90 7 80 3.40 4.20
2ec8A04 81.04 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 100 7 81 2.13 2.60
2cqvA00 80.72 Myosin light chain kinase activityProtein phosphorylationHomo sapiensMyosin light chain kinase, smooth muscle 2.60.40.10 114 12 80 2.86 3.54
1q0xL02 80.58 Mus musculusIg lambda-1 chain V regionProtein binding 2.60.40.10 100 11 79 3.19 4.04
1bihA02 80.57 Hyalophora cecropiaHemolin 2.60.40.10 106 9 83 2.92 3.48
1f2qA02 80.48 High affinity immunoglobulin epsilon receptor subunit alphaIntegral to plasma membraneHomo sapiensFc receptor, IgE, high affinity I, alpha polypeptideAsthma 2.60.40.10 90 14 77 3.47 4.50
2gy5A02 80.46 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 2.60.40.10 90 11 81 3.65 4.46
1witA00 80.39 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 93 7 84 3.04 3.59
3b4nA01 80.32 Erwinia chrysanthemiEndo-pectate lyase 2.60.40.10 88 10 80 3.12 3.90
1fltX00 80.15 Vascular endothelial growth factor receptor 1Integral to plasma membraneGrowth factor bindingVascular endothelial growth factor receptor activityFemale pregnancy 2.60.40.10 95 13 85 3.22 3.76
1cidA01 80.14 Rattus norvegicusT-cell surface glycoprotein CD4Hematopoietic cell lineageT cell receptor signaling pathwayAntigen processing and presentation 2.60.40.10 106 7 91 3.41 3.73
1ncnA00 80.11 T-lymphocyte activation antigen CD86Positive regulation of cell proliferationHomo sapiensImmune responseProtein binding 2.60.40.10 110 15 83 2.72 3.25
1cs6A02 80.01 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 89 21 80 3.25 4.06
1edqA01 79.99 Chitinase ASerratia marcescens 2.60.40.10 107 6 77 3.13 4.04
2gy5A01 79.97 Cell surfaceMicrovillusIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transduction 2.60.40.10 99 9 83 3.31 3.95
2e9wA01 79.94 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaExtracellular space 2.60.40.10 84 9 73 2.45 3.34
1o0vA01 79.85 Homo sapiensIg epsilon chain C region 2.60.40.10 102 14 81 3.61 4.41
1iamA01 79.80 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 83 14 75 2.70 3.59
1hzhH01 79.59 2.60.40.10 119 16 68 2.40 3.53
1t0pB00 79.50 Integral to plasma membraneIntercellular adhesion molecule 3Homo sapiensIntercellular adhesion molecule 3Cell adhesion molecules (CAMs) 2.60.40.10 86 11 78 2.58 3.30
1uvqA02 79.49 2.60.40.10 99 10 77 3.33 4.32
1n26A02 79.48 Positive regulation of chemokine productionPositive regulation of smooth muscle cell proliferationJak-STAT signaling pathwayAcute-phase responsePositive regulation of osteoblast differentiation 2.60.40.10 78 21 70 2.80 3.97
1xiwA00 79.45 Chagas diseaseHematopoietic cell lineageReceptor signaling protein activitySH3 domain bindingT cell receptor signaling pathway 2.60.40.10 91 13 79 3.62 4.58
1nctA00 79.39 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 16 85 2.75 3.21
1l6xA01 79.10 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 100 8 76 3.22 4.23
1ow0A02 78.94 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 109 11 77 3.40 4.36
3h9yA02 78.93 Homo sapiensIg epsilon chain C region 2.60.40.10 108 7 78 3.76 4.78
3b9eA01 78.93 Vibrio harveyiChitinase A 2.60.40.10 110 8 76 3.27 4.28
1cfbA01 78.80 Calcium ion bindingNeuron cell-cell adhesionNerve maturationDrosophila melanogasterEpidermal growth factor receptor signaling pathway 2.60.40.10 99 8 82 3.21 3.87
1itbB01 78.76 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 92 13 85 4.01 4.68
1pd6A00 78.75 Myosin-binding protein C, cardiac-typeHomo sapiensVentricular cardiac muscle tissue morphogenesisStriated muscle myosin thick filamentStructural constituent of muscle 2.60.40.10 94 17 82 3.26 3.93
1n26A01 78.68 Positive regulation of chemokine productionJak-STAT signaling pathwayPositive regulation of smooth muscle cell proliferationResponse to cytokine stimulusAcute-phase response 2.60.40.10 107 5 82 3.62 4.40
2bc4A02 78.64 HLA class II histocompatibility antigen, DM alpha chainHomo sapiensProtein binding 2.60.40.10 109 7 76 3.58 4.70
1l6xA02 78.55 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 106 10 78 3.75 4.79
3dbxA02 78.52 CD1-2 antigenGallus gallus 2.60.40.10 99 8 77 3.59 4.65
1cwvA03 78.36 InvasinYersinia pseudotuberculosis 2.60.40.920 102 9 78 3.35 4.29
1f6fB01 78.17 Rattus norvegicusProlactin receptorProlactin receptor activity 2.60.40.10 97 9 82 4.08 4.92
2ny1B02 77.95 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 75 16 68 2.77 4.04
1v05A00 77.83 Plasma membraneFilamin-CHomo sapiens 2.60.40.10 96 9 80 3.74 4.62
1clcA01 77.73 Clostridium thermocellumEndoglucanase D 2.60.40.10 102 6 73 2.68 3.65
3fruA02 77.70 IgG receptor FcRn large subunit p51Beta-2-microglobulin bindingRattus norvegicusHumoral immune responseIgG receptor activity 2.60.40.10 92 10 72 3.35 4.63
1g0dA03 77.63 Protein-glutamine gamma-glutamyltransferase 2Pagrus major 2.60.40.10 110 2 77 3.85 4.98
1dr9A02 77.50 Type I diabetes mellitusIntestinal immune network for IgA productionAutoimmune thyroid diseaseAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 95 8 77 3.65 4.73
1y6kR02 77.49 Interleukin-10 receptor activityPlasma membraneHomo sapiensInterleukin-10 receptor subunit alpha 2.60.40.10 103 4 72 2.96 4.09
1y6kR01 77.43 Interleukin-10 receptor activityPlasma membraneHomo sapiensInterleukin-10 receptor subunit alpha 2.60.40.10 102 3 81 3.46 4.22
1bquA01 77.36 Oncostatin-M receptor complexJak-STAT signaling pathwayResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 100 6 82 4.01 4.84
1mcpH02 77.34 Mus musculusIg heavy chain V region M603 2.60.40.10 99 9 78 3.61 4.62
1cd9B02 77.29 Mus musculusGranulocyte colony-stimulating factor receptorNeutrophil chemotaxis 2.60.40.10 98 6 80 3.71 4.58
3d9aH02 77.23 2.60.40.10 97 10 74 3.42 4.60
1ncwH02 77.23 2.60.40.10 99 10 76 3.35 4.40
1dn0D02 77.22 2.60.40.10 94 10 73 2.79 3.80
1ut9A01 77.16 Clostridium thermocellumCellobiohydrolase 2.60.40.10 98 5 77 3.09 4.01
1fyhB01 77.10 Jak-STAT signaling pathwayInterferon gamma receptor 1Integral to plasma membraneChagas diseaseInterferon-gamma receptor activity 2.60.40.10 97 7 80 3.69 4.61
1hxmB02 77.09 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 105 7 80 3.40 4.20
3cmgA04 76.96 Putative beta-galactosidaseBacteroides fragilis NCTC 9343 2.60.40.1560 87 4 73 3.27 4.46
1gsmA02 76.94 Membrane fractionMucosal vascular addressin cell adhesion molecule 1Intestinal immune network for IgA productionCell adhesionHomo sapiens 2.60.40.10 116 12 73 2.79 3.81
1qg3A01 76.78 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 91 8 80 3.37 4.21
2ec8A02 76.77 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 87 10 78 3.03 3.88
1k85A00 76.54 Bacillus circulansChitinase A1 2.60.40.10 88 15 76 3.78 4.96
2hftA01 76.43 Positive regulation of endothelial cell proliferationTissue factorPositive regulation of platelet-derived growth factor receptor signaling pathwayPositive regulation of angiogenesisProtease binding 2.60.40.10 103 1 82 3.68 4.44
1cd9D01 76.40 Mus musculusGranulocyte colony-stimulating factor receptorNeutrophil chemotaxis 2.60.40.10 107 4 83 3.82 4.59
1fnhA03 76.38 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 16 83 3.59 4.28
1seqH02 76.37 Rattus norvegicusIghg protein 2.60.40.10 98 10 77 3.45 4.47
3di2B02 76.30 Interleukin-7 receptor activityRegulation of DNA recombinationInterleukin-7 receptor subunit alphaHomo sapiensCell surface receptor linked signaling pathway 2.60.40.10 103 8 82 3.48 4.20
1bquA02 76.30 Jak-STAT signaling pathwayOncostatin-M receptor complexResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 108 9 78 3.34 4.24
1n26A03 76.29 Positive regulation of chemokine productionJak-STAT signaling pathwayPositive regulation of smooth muscle cell proliferationResponse to cytokine stimulusAcute-phase response 2.60.40.10 104 2 77 3.83 4.96
1fyhB02 76.23 Jak-STAT signaling pathwayInterferon gamma receptor 1Integral to plasma membraneChagas diseaseInterferon-gamma receptor activity 2.60.40.10 103 7 85 4.16 4.85
1ej6A05 76.21 Mammalian orthoreovirus 3 DearingOuter capsid protein lambda-2 2.60.40.10 95 8 84 3.91 4.61
3h9yB01 76.14 Homo sapiensIg epsilon chain C region 2.60.40.10 101 4 80 3.86 4.77
1j8kA00 76.10 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 94 10 84 3.77 4.45
2cumA00 76.04 Collagen metabolic processElastic fiber assemblyIntracellularHomo sapiensTenascin-X 2.60.40.10 105 6 82 3.52 4.25
1w8oA02 76.04 Micromonospora viridifaciensSialidase 2.60.40.10 102 9 82 3.81 4.60
1axiB02 76.04 Jak-STAT signaling pathwayCell surfaceMulticellular organismal metabolic processGrowth hormone receptor complexInsulin-like growth factor receptor signaling pathway 2.60.40.10 101 4 80 3.57 4.46
2gy5A04 76.02 MicrovillusCell surfaceTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transductionProtein binding 2.60.40.10 99 6 81 3.98 4.86
1f00I01 76.00 Pathogenic Escherichia coli infectionIntiminIntiminProtein bindingEscherichia coli O127:H6 str. E2348/69 2.60.40.920 95 8 74 3.50 4.71
1q72H02 75.84 2.60.40.10 89 10 69 3.24 4.66
1iarB02 75.53 Jak-STAT signaling pathwayInterleukin 4 receptorIntegral to plasma membraneReceptor signaling protein activityHematopoietic cell lineage 2.60.40.10 92 7 75 3.38 4.49
1ujtA00 75.32 LuteolysisPositive regulation of axonogenesisCell surfaceIdentical protein bindingHomophilic cell adhesion 2.60.40.10 120 7 74 3.57 4.81
1p53A03 75.23 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 83 13 73 2.93 4.00
1qr4A01 75.19 TenascinGallus gallus 2.60.40.10 87 5 80 3.52 4.35
2vxvH02 75.17 2.60.40.10 101 4 80 3.55 4.39
1cvrA03 74.91 Gingipain R [EC:3.4.22.37]Porphyromonas gingivalisGingipain R2 2.60.40.10 83 10 76 3.24 4.25
1im3D00 74.87 Unique short US2 glycoproteinHuman herpesvirus 5 strain AD169 2.60.40.1200 95 5 84 4.16 4.91
1fnhA02 74.87 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 90 10 83 4.14 4.94
2hftA02 74.85 Positive regulation of endothelial cell proliferationTissue factorPositive regulation of platelet-derived growth factor receptor signaling pathwayPositive regulation of angiogenesisProtease binding 2.60.40.10 102 3 66 3.12 4.68
1ji1A01 74.48 Neopullulanase 1Thermoactinomyces vulgaris 2.60.40.10 124 11 70 3.32 4.68
1ok8A04 74.32 Dengue virus 2 Puerto Rico/PR159-S1/1969Genome polyprotein 2.60.40.350 100 6 80 3.98 4.92
1dceA02 74.06 Rattus norvegicusRab geranylgeranyltransferase activityProtein geranylgeranyltransferase type II [EC:2.5.1.60]Geranylgeranyl transferase type-2 subunit alpha 2.60.40.1130 103 4 78 3.82 4.89
1fnhA01 73.94 FibronectinER-Golgi intermediate compartmentPeptide cross-linkingFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 90 6 80 3.91 4.83
2fnbA00 73.69 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 95 6 81 3.80 4.64
2mcmA00 73.67 MacromomycinStreptomyces macromomyceticus 2.60.40.230 112 5 75 3.41 4.55
1je6A02 73.14 Response to heatMHC class I polypeptide-related sequence BGamma-delta T cell activationImmune response-activating cell surface receptor signaling pathwayResponse to retinoic acid 2.60.40.10 89 11 77 3.85 4.99
Displaying entries 1 to 185 (page 1 of 1)


Domain ATOM Sequence

>pdb|2q20A00
TDIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQ
PEDIATYYCQQYDNLPYTFGQGTKLEIK    

Domain COMBS Sequence

>pdb|2q20A00
STDIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSL
QPEDIATYYCQQYDNLPYTFGQGTKLEIK    

Domain History Events (12)

Domain assigned by auto on 12 Apr 2008 14:34

Assigning to "2.60.40.10" based on similarity with "2q20B00"

Flow stage update by auto on 12 Apr 2008 14:34

No in_process hits for Domain "2q20A00" ready to be processed

Update comment by auto on 12 Apr 2008 14:32

Domain "2q20A00" hits Domain "2q20B00" (100% over 100%) which is currently in process

Update comment by auto on 12 Apr 2008 14:29

Domain "2q20A00" hits Domain "2q1eB00" (92.6605504587156% over 100%) which is currently in process

Update comment by auto on 12 Apr 2008 14:27

Domain "2q20A00" hits Domain "2q1eA00" (92.6605504587156% over 100%) which is currently in process

Update comment by auto on 12 Apr 2008 14:25

Domain "2q20A00" hits Domain "2q1eC00" (92.6605504587156% over 100%) which is currently in process

Update comment by auto on 12 Apr 2008 14:19

Domain "2q20A00" hits Domain "2q1eD00" (92.6605504587156% over 100%) which is currently in process

Flow stage update by auto on 12 Apr 2008 14:06

Domain "2q20A00" hits Domain "2q1eD00" (92.6605504587156% over 100%) which is currently in process

Flow stage update by auto on 12 Apr 2008 14:06

NW result present for Domain "2q20A00"

Flow stage update by auto on 12 Apr 2008 08:09

All required files are present for Domain "2q20A00"

Flow stage update by auto on 11 Apr 2008 11:48

Beginning processing for Domain "2q20A00"

Insertion by auto on 11 Apr 2008 11:23

Final ChopClose added based on similarity with "2q20B"