CATH Domain: 2p1jB02 XML data for domain: 2p1jB02

Molscript image for 2p1jB02
2p1jB02
PDB coordinates for domain 2p1jB02

PDB 2p1j, Chain B, Domain 2

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.140 Gene3D
1.20.5.140.2
1.20.5.140.2.1
1.20.5.140.2.1.1
1.20.5.140.2.1.1.1
1.20.5.140.2.1.1.1.1

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Segment boundaries for domain 2p1jB02

Chopping figure for domain 2p1jB02
DomainStart PDB ResidueStop PDB Residue
2p1jB01 357 494
2p1jB02 495 520

Structural Neighbourhood (75 entries)

There are 75 matching structural neighberhood comparisons for CATH ID 1.20.5.140.2.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 75 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1omiA02 88.57 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 3 96 2.95 3.06
2p10B02 87.85 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 3 80 1.21 1.50
1h8bB00 87.21 TitinOryctolagus cuniculus 1.20.5.510 23 13 69 0.37 0.53
2r44A01 86.83 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 7 73 0.52 0.71
1ozhA03 85.99 Acetolactate synthase, catabolicKlebsiella pneumoniae 1.20.5.740 24 8 88 2.99 3.38
1kmiZ01 85.91 Bacterial chemotaxisChemotaxis protein cheZProtein bindingChemotaxis protein CheZEscherichia coli K-12 1.20.5.590 30 11 86 2.49 2.87
1ow6A01 85.61 Focal adhesion kinase 1Focal adhesionCytoskeletonIntegrin-mediated signaling pathwayHomo sapiens 1.20.5.540 30 7 86 4.15 4.79
1a2xB00 85.46 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 7 77 1.98 2.56
1mqsB00 85.36 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 0 92 3.66 3.96
1slqF02 84.67 Outer capsid protein VP4Rhesus rotavirus 1.20.5.170 32 7 81 3.79 4.66
1dp5B00 84.46 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 3 77 2.28 2.94
2o01J01 84.37 Photosystem I reaction center subunit IXSpinacia oleracea 1.20.5.510 25 4 80 1.78 2.20
1vf5C03 84.34 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 15 75 2.18 2.91
1fdoA05 84.27 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 0 88 3.06 3.44
2hr3A01 84.16 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 7 66 1.38 2.07
1be3K00 83.97 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 13 84 2.72 3.21
3clqB01 83.77 Enterococcus faecalisPutative uncharacterized protein 1.20.5.220 24 8 88 4.04 4.57
1s3jB01 82.74 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 7 83 2.73 3.28
1owaA01 82.72 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 7 81 2.37 2.92
2qjyC01 82.57 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 11 78 2.85 3.62
1tiiC00 82.13 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 7 58 0.83 1.42
2g8yA03 82.03 Uncharacterized oxidoreductase [EC:1.1.1.-]Uncharacterized oxidoreductase ybiCEscherichia coli K-12 1.20.5.460 28 7 78 2.25 2.86
2zxeB01 81.97 1.20.5.170 35 0 71 3.00 4.20
1vl2B03 81.77 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 30 3 76 1.92 2.50
2g3aA01 81.63 Agrobacterium tumefaciens str. C58Acetyltransferase 1.20.5.540 31 7 83 3.86 4.60
1vl2A03 81.38 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 32 7 78 3.18 4.07
1qexA01 81.06 Enterobacteria phage T4Baseplate structural protein Gp9 1.20.5.960 35 0 74 2.97 4.00
2qiwA02 81.04 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 16 69 2.43 3.51
2p7jB01 81.00 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 7 64 2.64 4.12
1s5lX00 81.00 Photosystem II reaction center X proteinThermosynechococcus elongatus BP-1 1.20.5.510 40 3 55 0.99 1.80
2i8dA02 80.64 Hypothetical proteinLactobacillus casei ATCC 334Putative uncharacterized protein 1.20.5.420 30 7 66 2.88 4.32
1jekA00 80.31 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 7 65 3.02 4.65
1ltsC00 80.18 Heat-labile enterotoxin A chainEscherichia coli 1.20.5.240 41 3 58 2.15 3.67
1g2cB00 80.10 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 7 65 2.89 4.45
2o1kA00 79.83 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 3 61 2.33 3.76
1lghB00 79.80 Phaeospirillum molischianumLight-harvesting protein B-800/850 beta 1 chain 1.20.5.250 43 3 60 2.19 3.62
1kilE00 79.71 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 7 56 1.86 3.32
2h88C01 79.03 Gallus gallusSuccinate dehydrogenase cytochrome b, large subunit 1.20.5.540 31 7 58 2.64 4.55
1go9A00 78.95 1.20.5.480 39 15 66 2.54 3.81
3c8vA04 78.76 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 0 73 2.72 3.72
1onvB00 78.75 CTD phosphatase activityProtein dephosphorylationHomo sapiensRNA polymerase II subunit A C-terminal domain phosphataseDNA-directed RNA polymerase activity 1.20.5.670 21 9 76 2.76 3.59
1d66B02 78.68 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 20 57 1.07 1.85
1m56D00 78.57 Rhodobacter sphaeroidesAa3-type cytochrome c oxidase subunit IV 1.20.5.160 42 7 61 2.96 4.78
1qgkB00 78.43 DNA metabolic processG2 phase of mitotic cell cycleNuclear localization sequence bindingRegulation of DNA recombinationImportin subunit alpha-2 1.20.5.690 44 7 59 2.30 3.89
1czqA00 78.36 1.20.5.170 45 3 53 1.95 3.66
2pjuD03 78.13 Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity 1.20.5.170 41 11 53 1.69 3.15
2wscH01 77.96 Photosystem I reaction center subunit VI, chloroplasticSpinacia oleracea 1.20.5.220 23 8 80 2.41 2.98
1f8vE00 77.90 Pariacato virusProtein alpha 1.20.5.280 21 0 80 3.83 4.74
1hf9A00 77.88 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 3 63 2.08 3.28
1junA00 77.73 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 3 60 2.66 4.40
1r8eA03 77.63 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 7 59 2.11 3.57
1kqfB03 77.52 Two-component systemMetabolic pathwaysGlyoxylate and dicarboxylate metabolismMethane metabolismFormate dehydrogenase activity 1.20.5.480 44 7 59 2.76 4.67
1kv4A00 77.49 Moricin-1Bombyx mori 1.20.5.750 42 7 61 3.00 4.85
1nkzB00 77.22 Rhodoblastus acidophilusLight-harvesting protein B-800/850 beta chain 1.20.5.250 41 7 63 2.62 4.13
1ifpA00 77.08 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 11 59 2.79 4.72
1hj0A00 76.94 Bos taurusThymosin beta-10 1.20.5.520 41 7 63 3.02 4.76
1mslA02 76.88 1.20.5.220 18 16 69 3.10 4.48
1mkmA02 76.62 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 14 53 0.71 1.32
2oarE02 76.58 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 13 73 3.27 4.47
2oarA02 76.42 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 11 65 2.44 3.73
1u57A00 75.92 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 15 52 2.10 4.03
3effK02 75.83 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 7 57 2.45 4.24
3kpeA00 75.16 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 7 55 2.53 4.57
1jm0A00 75.10 1.20.5.420 48 15 47 2.04 4.26
1wmkA03 74.74 Death-associated protein kinase 2Bladder cancerIdentical protein bindingPathways in cancerATP binding 1.20.5.460 28 0 67 3.23 4.76
1jcdB00 74.74 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 7 50 2.15 4.30
1ci6B00 74.61 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 7 55 2.65 4.79
3cx5E01 74.05 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 7 47 2.24 4.74
1byyA00 73.24 Initial segmentVoltage-gated sodium channel complexRattus norvegicusSodium channel protein type 2 subunit alphaSodium ion transport 1.20.5.150 21 9 80 3.81 4.72
1jnmA00 72.94 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 11 46 2.29 4.93
1pfiA00 72.82 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 7 45 1.51 3.31
1l2pA00 71.75 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 19 34 1.05 3.05
1dh3A00 71.61 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 7 40 1.68 4.20
2o01N01 68.53 Phaseolus vulgarisPhotosystem I-N subunit 1.20.5.740 22 9 84 4.03 4.76
1m8oB00 67.67 Positive regulation of endothelial cell migrationPlatelet-derived growth factor receptor bindingPositive regulation of endothelial cell proliferationActivation of protein kinase activityRegulation of bone resorption 1.20.5.630 47 0 44 1.98 4.43
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Displaying entries 1 to 75 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2p1jB02
GPFRHHRALDDARVTAQVFLRFVEMM
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2p1jB02
GPFRHHRALDDARVTAQVFLRFVEMM
BLAST against CATH

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Domain History Events (59)

Domain assigned by cuff on 20 May 2008 14:04

same superfamily

Domain assignment manual match h by cuff on 20 May 2008 14:04

same superfamily

Domain assignment manual match t by tronnberg on 18 Sep 2007 10:32

SSAP: 88.6 OV: 96 SEQ: 3. Do not share the same function. none of the matches on the scan list with a CATH code and a SSAP score of at least 70 has the same function as the query.

Homcheck review by tronnberg on 18 Sep 2007 10:32

SSAP: 88.6 OV: 96 SEQ: 3. Do not share the same function. none of the matches on the scan list with a CATH code and a SSAP score of at least 70 has the same function as the query.

Flow stage update by tronnberg on 18 Sep 2007 10:32

SSAP: 88.6 OV: 96 SEQ: 3. Do not share the same function. none of the matches on the scan list with a CATH code and a SSAP score of at least 70 has the same function as the query.

Homcheck allotment by tronnberg on 18 Sep 2007 10:25

User 'tronnberg' has allocated a domain to themselves for HomChecking with comment : Grabbed this domain via HomCheck's "Get Me A Domain" button.

Flow stage update by tronnberg on 18 Sep 2007 10:25

User 'tronnberg' has allocated a domain to themselves for HomChecking with comment : Grabbed this domain via HomCheck's "Get Me A Domain" button.

Flow stage update by auto on 15 Sep 2007 19:40

Domain "2p1jB02" SCOP scan with no results - no SCOP mapping

Domain scan scop cath by auto on 15 Sep 2007 19:39

Adding scan of type "DOMAIN_SCAN_SCOP_CATH" with 0 results for 2p1jB02

Flow stage update by auto on 15 Sep 2007 15:45

Retrieved PRC_PFAMCATH results for job ID SID7642657652454250 and results inserted.

Domain scan prc pfamcath by auto on 15 Sep 2007 15:44

Adding scan of type "DOMAIN_SCAN_PRC_PFAMCATH" with 8 results for 2p1jB02

Update comment by auto on 15 Sep 2007 09:18

PRC_PFAMCATH job SID7642657652454250 is not yet finished.

Prc pfamcath submit by auto on 15 Sep 2007 08:42

The entry "2p1jB02" has been submitted to the PRC_PFAMCATH webservice.

Flow stage update by auto on 15 Sep 2007 08:42

The entry "2p1jB02" has been submitted to the PRC_PFAMCATH webservice.

Flow stage update by auto on 14 Sep 2007 23:51

Retrieved SSAP results for job ID SID0192564868829088 and results inserted.

Domain scan ssap cath by auto on 14 Sep 2007 23:50

Adding scan of type "DOMAIN_SCAN_SSAP_CATH" with 478 results for 2p1jB02

Update comment by auto on 09 Sep 2007 23:11

SSAP job SID0192564868829088 is not yet finished.

Ssap cath submit by auto on 09 Sep 2007 22:29

The entry "2p1jB02" has been submitted to the SSAP webservice.

Flow stage update by auto on 09 Sep 2007 22:29

The entry "2p1jB02" has been submitted to the SSAP webservice.

Flow stage update by auto on 09 Sep 2007 20:02

Giving up on SSAP job SID4611048576215616 because submission time of Wed Sep 5 16:25:42 2007 is more than 345600 seconds older than current time (Sun Sep 9 20:02:06 2007).

Update comment by auto on 05 Sep 2007 19:46

SSAP job SID4611048576215616 is not yet finished.

Flow stage update by auto on 05 Sep 2007 16:25

The entry "2p1jB02" has been submitted to the SSAP webservice.

Ssap cath submit by auto on 05 Sep 2007 16:25

The entry "2p1jB02" has been submitted to the SSAP webservice.

Flow stage update by auto on 05 Sep 2007 11:01

Retrieved PRC results for job ID SID0792358463410880 and inserted them into the database.

Domain scan prc cath by auto on 05 Sep 2007 11:00

Adding scan of type "DOMAIN_SCAN_PRC_CATH" with 7 results for 2p1jB02

Flow stage update by auto on 05 Sep 2007 04:00

The entry "2p1jB02" has been submitted to the PRC webservice.

Prc cath submit by auto on 05 Sep 2007 04:00

The entry "2p1jB02" has been submitted to the PRC webservice.

Flow stage update by auto on 04 Sep 2007 23:41

Retrieved HMM(SAM) results for job ID SID8355965087014644 and inserted them into the database.

Domain scan sam cath by auto on 04 Sep 2007 23:40

Adding scan of type "DOMAIN_SCAN_SAM_CATH" with 1 results for 2p1jB02

Update comment by auto on 04 Sep 2007 12:18

HMM(SAM) job SID8355965087014644 is not yet finished.

Sam cath submit by auto on 04 Sep 2007 10:11

The entry "2p1jB02" has been submitted to the HMM (SAM) webservice.

Flow stage update by auto on 04 Sep 2007 10:11

The entry "2p1jB02" has been submitted to the HMM (SAM) webservice.

Flow stage update by auto on 04 Sep 2007 03:54

Retrieved "2p1jB02" CATHEDRAL results for job ID SID5092589547838528 and inserted them into the database.

Domain scan cathedral cath by auto on 04 Sep 2007 03:53

Adding scan of type "DOMAIN_SCAN_CATHEDRAL_CATH" with 0 results for 2p1jB02

Cathedral cath submit by auto on 03 Sep 2007 14:15

The entry "2p1jB02" has been submitted to the CATHEDRAL webservice.

Flow stage update by auto on 03 Sep 2007 14:15

The entry "2p1jB02" has been submitted to the CATHEDRAL webservice.

Flow stage update by auto on 03 Sep 2007 12:19

ScanList with 11099 domains written to "/cath/data/current/scanlists/cathdb_current.fletcher/2p1jB02.scanlist" for "2p1jB02"

Write scan list by auto on 03 Sep 2007 12:19

Writing ScanList containing 11099 domains to file "/cath/data/current/scanlists/cathdb_current.fletcher/2p1jB02.scanlist" for domain "2p1jB02"

Update comment by auto on 03 Sep 2007 10:11

Waiting for 18 new domains (example : 2qg4C01) to be processed so that they can be scanned against too.

Update comment by auto on 03 Sep 2007 06:31

Waiting for 73 new domains (example : 2q3eK03) to be processed so that they can be scanned against too.

Update comment by auto on 03 Sep 2007 02:36

Waiting for 140 new domains (example : 2q08A02) to be processed so that they can be scanned against too.

Update comment by auto on 02 Sep 2007 22:32

Waiting for 188 new domains (example : 2o3jA01) to be processed so that they can be scanned against too.

Update comment by auto on 02 Sep 2007 18:22

Waiting for 279 new domains (example : 2b43C04) to be processed so that they can be scanned against too.

Update comment by auto on 02 Sep 2007 14:22

Waiting for 351 new domains (example : 1sh0B02) to be processed so that they can be scanned against too.

Update comment by auto on 02 Sep 2007 10:15

Waiting for 431 new domains (example : 1r0kA03) to be processed so that they can be scanned against too.

Update comment by auto on 02 Sep 2007 02:28

Waiting for 551 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Update comment by auto on 01 Sep 2007 22:12

Waiting for 607 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Update comment by auto on 01 Sep 2007 18:15

Waiting for 686 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Update comment by auto on 01 Sep 2007 14:16

Waiting for 771 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Update comment by auto on 01 Sep 2007 11:41

Waiting for 841 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Update comment by auto on 01 Sep 2007 06:15

Waiting for 903 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Update comment by auto on 01 Sep 2007 03:32

Waiting for 969 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Update comment by auto on 31 Aug 2007 20:06

Waiting for 1085 new domains (example : 1bplB01) to be processed so that they can be scanned against too.

Flow stage update by auto on 31 Aug 2007 20:01

No satisfactory AssignClose result found.

Flow stage update by auto on 31 Aug 2007 19:48

No in_process hits for Domain "2p1jB02" ready to be processed

Flow stage update by auto on 31 Aug 2007 19:48

NW result present for Domain "2p1jB02"

Flow stage update by auto on 25 Aug 2007 10:04

All required files are present for Domain "2p1jB02"

Flow stage update by auto on 24 Aug 2007 18:10

Beginning processing for Domain "2p1jB02"

Insertion by cuff on 24 Aug 2007 15:16

nice chopping