CATH Domain: 2p1jA02 XML data for domain: 2p1jA02

Molscript image for 2p1jA02
2p1jA02
PDB coordinates for domain 2p1jA02

PDB 2p1j, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.140 Gene3D
1.20.5.140.1
1.20.5.140.1.1
1.20.5.140.1.1.1
1.20.5.140.1.1.1.1
1.20.5.140.1.1.1.1.1

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Segment boundaries for domain 2p1jA02

Chopping figure for domain 2p1jA02
DomainStart PDB ResidueStop PDB Residue
2p1jA01 357 494
2p1jA02 495 520

Structural Neighbourhood (79 entries)

There are 79 matching structural neighberhood comparisons for CATH ID 1.20.5.140.1.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 79 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2p1jB02 89.96 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 100 100 1.86 1.86
1omiA02 89.67 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 7 92 2.46 2.66
1ozhA03 88.95 Acetolactate synthase, catabolicKlebsiella pneumoniae 1.20.5.740 24 4 80 1.58 1.96
1h8bB00 88.17 TitinOryctolagus cuniculus 1.20.5.510 23 26 84 1.79 2.12
2p10B02 87.79 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 3 76 0.98 1.27
1fdoA05 86.67 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 3 74 1.52 2.05
2hr3A01 86.34 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 11 80 2.83 3.54
2r44A01 86.23 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 7 73 0.94 1.29
1kmiZ01 86.22 Bacterial chemotaxisChemotaxis protein cheZProtein bindingChemotaxis protein CheZEscherichia coli K-12 1.20.5.590 30 11 86 2.24 2.58
1be3K00 85.90 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 13 84 2.55 3.01
3clqB01 85.61 Enterococcus faecalisPutative uncharacterized protein 1.20.5.220 24 8 88 3.97 4.49
1a2xB00 85.58 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 7 77 1.99 2.57
2oarA02 85.17 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 5 65 0.48 0.73
1slqF02 84.95 Outer capsid protein VP4Rhesus rotavirus 1.20.5.170 32 3 81 2.62 3.22
1mqsB00 84.80 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 0 88 3.10 3.50
1piqA00 84.40 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 3 74 2.47 3.33
2o01J01 84.38 Photosystem I reaction center subunit IXSpinacia oleracea 1.20.5.510 25 8 88 2.75 3.11
2oarE02 84.10 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 9 76 2.46 3.20
2qjyC01 84.09 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 11 78 2.44 3.10
1vf5C03 83.99 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 15 75 2.19 2.92
2zxeB01 83.96 1.20.5.170 35 0 71 2.47 3.46
1s3jB01 83.81 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 7 73 2.20 3.00
1wa9B03 83.46 Regulation of circadian sleep/wake cycle, sleepPeriod circadian proteinNucleusResponse to temperature stimulusNegative regulation of transcription from RNA polymerase II promoter 1.20.5.770 33 15 78 2.91 3.69
1jmmA01 83.30 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 11 78 2.13 2.73
2g8yA03 82.89 Uncharacterized oxidoreductase [EC:1.1.1.-]Uncharacterized oxidoreductase ybiCEscherichia coli K-12 1.20.5.460 28 11 78 2.29 2.91
1qexA01 82.88 Enterobacteria phage T4Baseplate structural protein Gp9 1.20.5.960 35 0 74 2.70 3.63
2p7jB01 82.15 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 11 66 2.96 4.44
1jekA00 81.81 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 7 65 2.20 3.38
1dp5B00 81.77 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 15 67 2.58 3.81
1vl2B03 81.74 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 30 3 76 1.66 2.17
1ow6A01 81.61 Focal adhesion kinase 1Focal adhesionCytoskeletonIntegrin-mediated signaling pathwayHomo sapiens 1.20.5.540 30 7 73 2.85 3.89
1d66B02 81.29 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 20 57 0.52 0.90
1g2cB00 81.10 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 7 65 3.10 4.77
1vl2A03 80.97 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 32 7 78 3.52 4.51
1nkzB00 80.95 Rhodoblastus acidophilusLight-harvesting protein B-800/850 beta chain 1.20.5.250 41 7 63 1.85 2.92
1hf9A00 80.30 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 7 63 2.60 4.10
1f8vD00 79.81 Pariacato virusProtein alpha 1.20.5.280 25 12 84 3.97 4.69
1go9A00 79.75 1.20.5.480 39 19 66 2.77 4.16
2k1aA00 79.62 Integrin alpha 2BIdentical protein bindingPathways in cancerHematopoietic cell lineageDilated cardiomyopathy 1.20.5.930 42 0 61 2.66 4.30
2o1kA00 79.45 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 3 57 2.49 4.36
1nafA01 79.35 ADP-ribosylation factor-binding protein GGA1Homo sapiensProtein bindingIntracellular protein transport 1.20.5.170 36 0 63 3.00 4.70
2qiwA02 79.19 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 16 69 2.20 3.18
2h88C01 78.99 Gallus gallusSuccinate dehydrogenase cytochrome b, large subunit 1.20.5.540 31 7 61 2.12 3.46
1ltsC00 78.85 Heat-labile enterotoxin A chainEscherichia coli 1.20.5.240 41 3 63 3.05 4.81
2pjuD03 78.84 Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity 1.20.5.170 41 11 53 1.78 3.32
1owaA01 78.80 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 7 71 2.71 3.77
1dipB01 78.80 Sus scrofaTSC22 domain family protein 3 1.20.5.490 45 3 57 2.32 4.02
3c8vA04 78.75 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 5 57 0.97 1.68
1kv4A00 78.41 Moricin-1Bombyx mori 1.20.5.750 42 7 61 2.64 4.26
1r8eA03 78.33 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 11 59 2.63 4.45
1czqA00 78.25 1.20.5.170 45 3 55 1.98 3.56
1mkmA02 78.24 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 14 53 0.65 1.21
2v7qJ00 77.90 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 43 7 60 2.45 4.05
3kpeA00 77.73 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 7 55 2.35 4.25
1kqfB03 77.69 Two-component systemMetabolic pathwaysGlyoxylate and dicarboxylate metabolismMethane metabolismFormate dehydrogenase activity 1.20.5.480 44 15 59 2.13 3.60
1onvB00 77.66 CTD phosphatase activityProtein dephosphorylationHomo sapiensRNA polymerase II subunit A C-terminal domain phosphataseDNA-directed RNA polymerase activity 1.20.5.670 21 9 76 2.88 3.74
1junA00 77.52 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 15 60 2.76 4.56
1mslA02 77.46 1.20.5.220 18 0 69 2.12 3.06
1u57A00 77.08 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 26 54 2.33 4.30
1ifpA00 76.86 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 19 59 2.40 4.06
3e7kA00 76.69 Rattus norvegicusCalcium channel activityCalcium ion transportIntegral to membraneProtein binding 1.20.5.1010 54 0 46 1.76 3.80
1hj0A00 76.53 Bos taurusThymosin beta-10 1.20.5.520 41 3 51 1.45 2.83
1f8vE00 76.36 Pariacato virusProtein alpha 1.20.5.280 21 14 76 3.62 4.71
3b8eB00 75.64 Sodium/potassium-transporting ATPase subunit beta-1Sus scrofa 1.20.5.170 46 0 56 2.39 4.23
1t6aA01 75.59 Geobacillus stearothermophilusRbstp2229 protein 1.20.5.850 43 7 51 2.09 4.08
1ik7A00 75.53 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 7 50 2.46 4.92
1xrdA01 75.29 Light-harvesting complex 1 alpha chainRhodospirillum rubrumLight-harvesting protein B-870 alpha chain 1.20.5.890 43 15 60 2.80 4.63
2zjsE00 75.13 Protein exportBacterial secretion systemThermus thermophilus HB8Preprotein translocase subunit secEPreprotein translocase subunit SecE 1.20.5.1030 46 7 56 2.63 4.65
1gk6B00 74.36 Positive regulation of RNA polymerase II transcriptional preinitiation complex assemblyIntermediate filamentVimentinCytosolPositive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.170 52 3 50 2.25 4.50
1a02F00 74.17 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 7 47 2.22 4.71
2jdiH02 73.30 F-type H+-transporting ATPase subunit delta [EC:3.6.3.14]Huntington's diseaseOxidative phosphorylationParkinson's diseaseBos taurus 1.20.5.440 42 3 50 2.39 4.78
1nwqA00 72.84 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 3 43 1.72 3.97
1vq8P02 72.65 50S ribosomal protein L19eRibosomeLarge subunit ribosomal protein L19eHaloarcula marismortui 1.20.5.560 33 7 51 2.51 4.87
1m7lA00 72.56 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 11 65 2.70 4.15
2wscH01 72.32 Photosystem I reaction center subunit VI, chloroplasticSpinacia oleracea 1.20.5.220 23 4 69 2.93 4.23
1pfiA00 71.95 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 7 45 1.78 3.90
1dh3A00 71.93 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 7 40 1.38 3.45
1gu4A00 71.85 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 3 40 1.77 4.42
2e5yA02 70.66 ATP synthase epsilon chainBacillus sp. PS3 1.20.5.440 45 7 35 0.86 2.42
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Displaying entries 1 to 79 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2p1jA02
GPFRHHRALDDARVTAQVFLRFVEMM
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2p1jA02
GPFRHHRALDDARVTAQVFLRFVEMMKKEGHHHHHH
BLAST against CATH

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Domain History Events (8)

Domain assigned by auto on 20 May 2008 14:21

Assigning to "1.20.5.140" based on similarity with "2pajA03"

Flow stage update by auto on 20 May 2008 14:08

No in_process hits for Domain "2p1jA02" ready to be processed

Update comment by auto on 06 Sep 2007 22:06

Domain "2p1jA02" hits Domain "2p1jB02" (100% over 72.2222222222222%) which is currently in process

Flow stage update by auto on 06 Sep 2007 22:05

Domain "2p1jA02" hits Domain "2p1jB02" (100% over 72.2222222222222%) which is currently in process

Flow stage update by auto on 06 Sep 2007 22:05

NW result present for Domain "2p1jA02"

Flow stage update by auto on 04 Sep 2007 14:04

All required files are present for Domain "2p1jA02"

Flow stage update by auto on 03 Sep 2007 20:09

Beginning processing for Domain "2p1jA02"

Insertion by cuff on 03 Sep 2007 14:12

nice chopping