CATH Domain: 2ooqA00 XML data for domain: 2ooqA00

Molscript image for 2ooqA00
2ooqA00
PDB coordinates for domain 2ooqA00

PDB 2ooq, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.90 Alpha-Beta Complex
3.90.190 Protein-Tyrosine Phosphatase; Chain A
3.90.190.10 Protein tyrosine phosphatase superfamily Gene3D
3.90.190.10.7
3.90.190.10.7.1
3.90.190.10.7.1.1
3.90.190.10.7.1.1.1
3.90.190.10.7.1.1.1.1

Segment boundaries for domain 2ooqA00

Chopping figure for domain 2ooqA00
DomainStart PDB ResidueStop PDB Residue
2ooqA00 889 1168

Structural Neighbourhood (7 entries)

There are 7 matching structural neighberhood comparisons for CATH ID 3.90.190.10.7.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 7 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2i1yA00 90.80 Protein tyrosine phosphatase, receptor type, N [EC:3.1.3.48]Transmembrane receptor protein tyrosine phosphatase activityType I diabetes mellitusIntegral to plasma membraneHomo sapiens 3.90.190.10 285 34 93 2.32 2.48
1p15B00 89.83 Mus musculusProtein phosphorylationReceptor-type tyrosine-protein phosphatase alphaInsulin receptor signaling pathway 3.90.190.10 246 41 86 1.26 1.46
1g4wR02 81.65 Salmonella enterica subsp. enterica serovar TyphimuriumSecreted effector protein sptPSecreted effector protein SptPProtein binding 3.90.190.10 221 14 73 2.33 3.15
1d5rA01 75.55 Tight junctionGliomaFocal adhesionP53 signaling pathwayPhosphatidylinositol signaling system 3.90.190.10 174 16 56 2.55 4.48
1oheA02 75.15 Protein serine/threonine phosphatase activityProtein tyrosine phosphatase activityHomo sapiensProtein bindingDual specificity protein phosphatase CDC14B 3.90.190.10 169 17 54 2.55 4.69
3f81A00 73.98 Negative regulation of ERK1 and ERK2 cascadePositive regulation of mitotic cell cycleInactivation of MAPK activityNegative regulation of JNK cascadeCytosol 3.90.190.10 179 7 61 3.06 5.00
2r0bA00 73.87 Homo sapiensSerine/threonine/tyrosine-interacting protein 3.90.190.10 148 10 53 2.66 4.96
Displaying entries 1 to 7 (page 1 of 1)


Domain ATOM Sequence

>pdb|2ooqA00
MAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDPHSDYINANYI
DGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRT
FTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEG
VVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLC    

Domain COMBS Sequence

>pdb|2ooqA00
SMAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINA
NYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYGDIKVTLIETEPLAEYV
IRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAE
NEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAI    

Domain History Events (6)

Domain assigned by auto on 12 Dec 2008 20:54

Assigning to "3.90.190.10" based on similarity with "1rpmA00"

Flow stage update by auto on 12 Dec 2008 20:36

No in_process hits for Domain "2ooqA00" ready to be processed

Flow stage update by auto on 12 Dec 2008 20:35

NW result present for Domain "2ooqA00"

Flow stage update by auto on 10 Dec 2008 14:16

All required files are present for Domain "2ooqA00"

Flow stage update by auto on 10 Dec 2008 14:15

Beginning processing for Domain "2ooqA00"

Insertion by auto on 08 Dec 2008 18:08

Final ChopClose added based on similarity with "1rpmA"