CATH Domain: 2ofhX00 XML data for domain: 2ofhX00

Molscript image for 2ofhX00
2ofhX00
PDB coordinates for domain 2ofhX00

PDB 2ofh, Chain X, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.70 Alpha-Beta Plaits
3.30.70.100 Gene3D
3.30.70.100.18
3.30.70.100.18.1
3.30.70.100.18.1.1
3.30.70.100.18.1.1.1
3.30.70.100.18.1.1.1.1

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Segment boundaries for domain 2ofhX00

Chopping figure for domain 2ofhX00
DomainStart PDB ResidueStop PDB Residue
2ofhX00 6 76

Structural Neighbourhood (97 entries)

There are 97 matching structural neighberhood comparisons for CATH ID 3.30.70.100.18.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 97 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2kt2A00 85.60 Mercuric reductasePseudomonas aeruginosaMercuric reductase [EC:1.16.1.1] 3.30.70.100 69 26 94 2.25 2.38
2fmrA00 80.49 CytoplasmSoluble fractionNucleolusHomo sapiensFragile X mental retardation 1 protein 3.30.1370.10 65 7 85 3.68 4.28
2j8sA07 80.31 Hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 familyAcriflavine resistance protein BProtein bindingEscherichia coli K-12 3.30.70.1440 94 2 75 3.17 4.20
2nyiA01 79.87 3.30.70.260 77 15 83 3.44 4.14
1u8sA02 79.78 Glycine cleavage system transcriptional repressor, putativeGlycine cleavage system transcriptional repressorVibrio cholerae 3.30.70.260 84 12 83 2.95 3.54
1harA02 79.34 Human immunodeficiency virus type 1 BH10Gag-Pol polyprotein 3.30.70.270 69 10 90 3.05 3.38
1u8sA01 79.29 Glycine cleavage system transcriptional repressor, putativeGlycine cleavage system transcriptional repressorVibrio cholerae 3.30.70.260 86 9 81 2.99 3.67
1fxlA01 78.97 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 71 8 88 3.42 3.85
2hiyB01 78.92 Streptococcus pneumoniaePutative uncharacterized protein 3.30.70.1280 87 11 75 3.10 4.09
1vr6A01 78.84 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysThermotoga maritima3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]Phospho-2-dehydro-3-deoxyheptonate aldolase 3.30.70.1140 75 5 89 3.28 3.67
1zpvB00 78.82 ACT domain-containing proteinUPF0237 protein SP_0238Streptococcus pneumoniae 3.30.70.260 81 11 82 3.64 4.40
1fjeB01 78.73 NucleolinMesocricetus auratus 3.30.70.330 81 11 82 3.52 4.26
2x3dF01 78.51 Hypothetical proteinSulfolobus solfataricusPutative uncharacterized protein 3.30.70.1340 84 12 77 3.15 4.07
2do0A01 78.50 Protein domain specific bindingIntegral to plasma membraneParaspecklesAlternative nuclear mRNA splicing, via spliceosomeHeterogeneous nuclear ribonucleoprotein M 3.30.70.330 76 12 88 3.54 4.02
1eayD00 78.38 Bacterial chemotaxisTwo-component systemTwo-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]Escherichia coli K-12Chemotaxis protein cheA 3.30.70.400 69 10 87 3.90 4.47
1kp6A00 78.32 Ustilago maydis virus P6KP6 killer toxin 3.30.70.440 79 5 77 3.69 4.78
1no8A00 78.31 THO complex subunit 4Mus musculusSpliceosomeSingle-stranded DNA bindingRNA binding 3.30.70.330 78 8 85 3.44 4.00
2ivyA01 77.98 Sulfolobus solfataricusPutative uncharacterized protein 3.30.70.240 74 4 83 4.18 4.99
2f1fA01 77.91 Valine, leucine and isoleucine biosynthesisMetabolic pathwaysButanoate metabolismC5-Branched dibasic acid metabolismPantothenate and CoA biosynthesis 3.30.70.260 79 9 87 3.50 4.01
2anrA02 77.81 RNA-binding protein Nova-1Synaptic transmissionHomo sapiensLocomotory behavior 3.30.1370.10 74 14 83 3.42 4.08
1s99A01 77.46 Bacillus subtilisPutative HMP/thiamine-binding protein ykoF 3.30.70.930 77 5 87 3.71 4.26
1i1gA02 77.46 Pyrococcus furiosusHTH-type transcriptional regulator lrpALrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA 3.30.70.920 77 8 83 3.78 4.55
3c19A01 77.45 Methanopyrus kandleriUncharacterized conserved protein 3.30.70.1380 98 14 66 2.59 3.90
1in0A02 77.39 Hypothetical proteinHaemophilus influenzaeUPF0234 protein HI_1034 3.30.70.990 92 8 65 3.24 4.97
1l3kA02 77.30 Heterogeneous nuclear ribonucleoprotein A1NucleolusProtein bindingCytoplasmSpliceosome 3.30.70.330 78 12 88 3.85 4.35
2od4B01 77.26 3.30.70.900 81 8 82 3.61 4.36
1q5yD00 77.22 CopG family transcriptional regulator, nickel-responsive regulatorNickel-responsive regulatorProtein bindingEscherichia coli K-12 3.30.70.1150 80 2 82 3.76 4.56
1u02A02 77.19 Trehalose-6-phosphate phosphatase related proteinThermoplasma acidophilum 3.30.70.1020 73 7 80 3.54 4.38
1mw7A03 77.13 Helicobacter pyloriUPF0082 protein HP_0162 3.30.70.980 75 8 80 3.55 4.44
1earA02 77.05 Sporosarcina pasteuriiUrease accessory protein ureE 3.30.70.790 69 8 78 3.72 4.72
2pehA01 76.92 Splicing factor 45SpliceosomeHomo sapiensProtein bindingSplicing factor 45 3.30.70.330 83 7 83 3.72 4.47
2fb0A00 76.91 Bacteroides thetaiotaomicronPutative uncharacterized protein 3.30.70.900 91 7 78 3.64 4.67
1konA03 76.86 UPF0082 protein yebCEscherichia coli K-12 3.30.70.980 75 9 78 3.64 4.63
2w25A02 76.81 Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory proteinLeucine-responsive regulatory proteinMycobacterium tuberculosis 3.30.70.920 81 9 82 3.97 4.80
1nh8A03 76.79 Histidine metabolismMetabolic pathwaysATP phosphoribosyltransferaseATP phosphoribosyltransferase [EC:2.4.2.17]Mycobacterium tuberculosis 3.30.70.120 67 10 84 3.59 4.25
2nyiA02 76.70 3.30.70.260 89 11 75 3.69 4.90
1gmuA01 76.66 Klebsiella aerogenesUrease accessory protein ureE 3.30.70.790 67 8 80 3.34 4.16
1cvjA01 76.60 Poly(A) RNA bindingTranslation activator activityProtein C-terminus bindingMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 77 11 84 3.47 4.11
1utaA00 76.58 Membrane fractionCell cycle cytokinesisCell division protein FtsNCell division protein ftsNProtein binding 3.30.70.1070 77 7 84 3.33 3.94
2errA01 76.47 Fox-1 homolog AProtein C-terminus bindingHomo sapiensTrans-Golgi network 3.30.70.330 83 5 83 3.24 3.90
2i0xA01 76.36 Pyrococcus furiosusPutative uncharacterized protein 3.30.70.240 66 4 84 4.03 4.77
3ce8A00 76.30 Shewanella baltica OS155Putative uncharacterized protein 3.30.70.120 87 9 74 2.89 3.87
2ia0B02 76.27 Pyrococcus furiosusUncharacterized HTH-type transcriptional regulator PF0864 3.30.70.920 99 15 64 2.78 4.30
2qfjA02 76.13 Homo sapiensPoly(U)-binding-splicing factor PUF60Protein binding 3.30.70.330 87 12 77 3.47 4.51
1x5uA01 76.13 SpliceosomeSpliceosomal complexHomo sapiensSplicing factor 3B subunit 4Splicing factor 3B subunit 4 3.30.70.330 80 7 80 3.39 4.24
2nuhA00 76.12 Xylella fastidiosaPeriplasmic divalent cation tolerance proteinPeriplasmic divalent cation tolerance protein 3.30.70.830 104 5 63 2.58 4.07
1s1tA02 76.03 HIV-1 M:B_HXB2RGag-Pol polyprotein 3.30.70.270 93 12 70 2.86 4.03
1cvjG02 76.02 Poly(A) RNA bindingProtein C-terminus bindingTranslation activator activityMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 88 7 78 3.58 4.57
2j8sA06 75.90 Hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 familyAcriflavine resistance protein BProtein bindingEscherichia coli K-12 3.30.70.1430 105 5 66 3.14 4.71
1s2oA02 75.89 Synechocystis sp. PCC 6803Slr0953 protein 3.90.1070.10 71 7 78 3.80 4.82
2j8sA02 75.84 Hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 familyAcriflavine resistance protein BProtein bindingEscherichia coli K-12 3.30.70.1430 103 11 68 3.36 4.87
1uv7A00 75.80 Vibrio choleraeGeneral secretion pathway protein M 3.30.1360.100 74 8 70 3.28 4.67
1o8bA02 75.77 Pentose phosphate pathwayMetabolic pathwaysRibose 5-phosphate isomerase A [EC:5.3.1.6]Escherichia coli K-12Ribose-5-phosphate isomerase A 3.30.70.260 69 10 83 3.75 4.51
1d8zA00 75.68 Mus musculusAU-rich element bindingELAV like protein 2/3/4ELAV-like protein 3 3.30.70.330 89 7 76 3.74 4.89
3h90A02 75.63 Ferrous-iron efflux pump FieFCellular cadmium ion homeostasisCellular zinc ion homeostasisCadmium ion transportEscherichia coli K-12 3.30.70.1350 84 7 73 3.50 4.74
1fxlA02 75.58 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 77 15 84 3.89 4.61
2j8sA03 75.56 Hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 familyAcriflavine resistance protein BProtein bindingEscherichia coli K-12 3.30.70.1320 100 11 70 3.36 4.80
1ufwA00 75.49 Phosphatidylinositol signaling systemSynaptojanin-2Phosphatidylinositol-bisphosphatase [EC:3.1.3.36]Homo sapiensInositol phosphate metabolism 3.30.70.330 95 8 72 3.33 4.58
3gygA02 75.45 Bacillus subtilisNTD biosynthesis operon putative hydrolase ntdB 3.30.70.1410 86 5 65 3.20 4.91
1nu4A00 75.35 U1 small nuclear ribonucleoprotein ASpliceosomeSpliceosomal complexHomo sapiensProtein binding 3.30.70.330 91 9 76 3.79 4.93
1x5oA01 75.33 RNA processingHomo sapiensProtein bindingRNA-binding motif, single-stranded-interacting protein 1 3.30.70.330 86 9 80 3.67 4.57
2aefA03 75.31 Methanothermobacter thermautotrophicus str. Delta HCalcium-gated potassium channel mthK 3.30.70.1450 79 11 78 3.85 4.91
1lfpA03 75.31 UPF0082 protein aq_1575Aquifex aeolicus 3.30.70.980 73 8 82 3.55 4.32
1xtzA02 75.22 Identical protein bindingNucleusRibose-5-phosphate isomerasePyridoxine biosynthetic processRibose 5-phosphate isomerase A [EC:5.3.1.6] 3.30.70.260 84 7 69 2.94 4.26
1vjqA00 75.17 3.30.70.340 71 4 88 4.18 4.71
1m1hA01 75.11 Transcriptional antiterminator NusGTranscription antitermination protein nusGAquifex aeolicus 3.30.70.940 100 15 66 3.24 4.91
1nzaA00 75.06 Thermus thermophilus HB8Divalent-cation tolerance protein cutAPeriplasmic divalent cation tolerance protein 3.30.70.830 103 14 64 3.14 4.90
1in0A01 75.02 Hypothetical proteinHaemophilus influenzaeUPF0234 protein HI_1034 3.30.70.860 70 8 83 3.93 4.73
1rk8A00 74.79 SpliceosomeRNA-binding protein 8AMicrotubule cytoskeleton organizationNucleusDrosophila melanogaster 3.30.70.330 87 8 81 3.57 4.37
1dloB02 74.67 Human immunodeficiency virus type 1 BH10Gag-Pol polyprotein 3.30.70.270 93 14 74 3.35 4.52
2zd1A02 74.66 Human immunodeficiency virus type 1 BH10Gag-Pol polyprotein 3.30.70.270 94 12 73 3.57 4.86
2wriY03 74.62 Thermus thermophilus HB8Elongation factor GElongation factor EF-G [EC:3.6.5.3] 3.30.70.870 76 9 86 4.31 4.96
1nm2A01 74.60 Fatty acid biosynthesisStreptomyces coelicolorMalonyl CoA:acyl carrier protein malonyltransferase[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]Metabolic pathways 3.30.70.250 68 8 81 3.91 4.79
1lfwA03 74.57 Lactobacillus delbrueckii subsp. lactisBeta-Ala-Xaa dipeptidase 3.30.70.360 88 8 70 3.47 4.93
1uw4A00 74.56 Regulator of nonsense transcripts 3BNuclear-transcribed mRNA catabolic process, nonsense-mediated decayHomo sapiensProtein binding 3.30.70.330 90 8 75 3.60 4.76
1iujB00 74.51 TT1380 proteinThermus thermophilus 3.30.70.900 103 5 67 3.36 4.94
3bm7A00 74.46 Caulobacter vibrioidesPutative uncharacterized protein 3.30.70.900 101 8 69 3.38 4.88
2dgsA01 74.42 CytoplasmDAZ-associated protein 1NucleusRNA bindingHomo sapiens 3.30.70.330 89 9 75 3.67 4.88
1q8bA00 74.42 Bacillus subtilisUncharacterized protein yjcS 3.30.70.900 89 9 78 3.56 4.53
1lwcB02 74.35 HIV-1 M:B_HXB2RGag-Pol polyprotein 3.30.70.270 87 12 77 3.42 4.44
1xmbA02 74.33 Auxin metabolic processArabidopsis thalianaIAA-Ala conjugate hydrolase activityIAA-amino acid hydrolase ILR1-like 2 3.30.70.360 101 16 70 3.28 4.67
3dlkB02 74.30 Human immunodeficiency virus type 1 BH10Gag-Pol polyprotein 3.30.70.270 98 12 69 3.27 4.71
1usmA00 74.23 Transcriptional coactivatorThermus thermophilus 3.30.1360.20 77 8 85 4.02 4.69
1qm9A02 74.14 Polypyrimidine tract-binding protein 1Poly-pyrimidine tract bindingHeterogeneous nuclear ribonucleoprotein complexMRNA processingNucleolus 3.30.70.330 89 1 79 3.84 4.81
2gx8C02 74.10 Bacillus cereus ATCC 14579NIF3-related protein 3.30.70.830 102 7 61 2.98 4.82
1mlaA01 73.98 Fatty acid biosynthesisMetabolic pathwaysMalonyl CoA-acyl carrier protein transacylase[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]Escherichia coli K-12 3.30.70.250 73 11 86 2.87 3.33
1darA05 73.95 Thermus thermophilus HB8Elongation factor GElongation factor EF-G [EC:3.6.5.3] 3.30.70.240 87 5 72 3.40 4.70
1kr4A00 73.92 Thermotoga maritimaDivalent-cation tolerance protein cutAPeriplasmic divalent cation tolerance protein 3.30.70.830 107 8 61 2.86 4.64
2hiyA02 73.62 Streptococcus pneumoniaePutative uncharacterized protein 3.30.70.1260 91 7 68 3.33 4.89
2bopA00 73.42 Regulatory protein E2Bovine papillomavirus type 1 3.30.70.330 85 4 75 3.69 4.90
3bzqA00 73.36 Two-component systemNitrogen regulatory protein P-II 1Nitrogen regulatory protein P-IIMycobacterium tuberculosis 3.30.70.120 99 16 65 2.86 4.36
1tr0A00 73.05 Populus tremulaStable protein 1 3.30.70.900 106 11 66 3.18 4.75
1cg2A02 72.97 Pseudomonas sp. RS-16Carboxypeptidase G2 3.30.70.360 110 12 61 3.06 4.95
1sxlA00 72.57 Sex differentiationDrosophila melanogasterProtein complexPoly-pyrimidine tract bindingNegative regulation of translation 3.30.70.330 97 8 72 3.53 4.89
1j27A00 72.28 Hypothetical proteinThermus thermophilusPutative uncharacterized protein 3.30.70.1120 98 11 71 3.09 4.33
2opsB02 72.10 HIV-1 M:B_HXB2RGag-Pol polyprotein 3.30.70.270 49 12 59 2.80 4.73
1qd1A02 71.53 Formimidoyltransferase-cyclodeaminaseOne carbon pool by folateSus scrofaFormiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4]Glutamate formiminotransferase [EC:2.1.2.5] 3.30.70.670 139 11 48 2.30 4.77
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Displaying entries 1 to 97 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2ofhX00
PLKTQQMQVGGMDCTSCKLKIEGSLERLKGVAEASVTVATGRLTVTYDPKQVSEITIQERIAALGYTLAEP
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2ofhX00
MTQSSPLKTQQMQVGGMDCTSCKLKIEGSLERLKGVAEASVTVATGRLTVTYDPKQVSEITIQERIAALGYTLAEP
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 22 Dec 2007 14:14

Assigning to "3.30.70.100" based on similarity with "1p6tA01"

Flow stage update by auto on 22 Dec 2007 14:04

No in_process hits for Domain "2ofhX00" ready to be processed

Flow stage update by auto on 22 Dec 2007 14:04

NW result present for Domain "2ofhX00"

Flow stage update by auto on 22 Dec 2007 08:05

All required files are present for Domain "2ofhX00"

Flow stage update by auto on 21 Dec 2007 08:33

Beginning processing for Domain "2ofhX00"

Insertion by auto on 21 Dec 2007 08:05

Final ChopClose added based on similarity with "1opzA"