CATH Domain: 2nw2A01 XML data for domain: 2nw2A01

Molscript image for 2nw2A01
2nw2A01
PDB coordinates for domain 2nw2A01

PDB 2nw2, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.14
2.60.40.10.14.1
2.60.40.10.14.1.1
2.60.40.10.14.1.1.1
2.60.40.10.14.1.1.1.1

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Segment boundaries for domain 2nw2A01

Chopping figure for domain 2nw2A01
DomainStart PDB ResidueStop PDB Residue
2nw2A01 1 116
2nw2A02 117 206

Structural Neighbourhood (157 entries)

There are 157 matching structural neighberhood comparisons for CATH ID 2.60.40.10.14.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 157 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2ak4D01 90.75 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 114 32 90 1.41 1.56
2ialA01 90.72 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 108 29 93 1.55 1.66
1u3hA00 90.05 Mus musculusTRAV14-3 2.60.40.10 110 34 92 1.49 1.61
1kgcD01 88.53 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 111 25 90 1.94 2.13
1lp9E01 88.51 2.60.40.10 113 38 91 1.69 1.85
2q8bH01 88.44 2.60.40.10 112 19 88 2.07 2.34
1ogaE01 88.35 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 111 25 90 2.41 2.68
1kgcE01 88.34 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 112 33 89 2.65 2.97
1mjuH01 88.01 2.60.40.10 115 19 89 2.24 2.50
1oaqL00 87.93 2.60.40.10 110 27 88 2.71 3.07
1pewA00 87.91 Ig lambda chain V-VI region SUTHomo sapiens 2.60.40.10 108 28 88 2.27 2.55
1x9qA01 87.52 2.60.40.10 111 27 84 2.37 2.80
2vxtH01 87.38 2.60.40.10 113 17 88 2.26 2.55
1tvdA00 87.18 Homo sapiensHDV103S1 2.60.40.10 116 29 88 2.02 2.27
2otuA00 87.11 2.60.40.10 115 27 86 2.33 2.71
1yc7A00 86.81 2.60.40.10 116 23 87 2.36 2.68
2aepL01 86.78 2.60.40.10 119 25 81 2.46 3.02
2v44A01 86.71 Prion diseasesNeural cell adhesion moleculeNeuron cell-cell adhesionPlasma membraneNeural cell adhesion molecule 2 2.60.40.10 94 11 83 2.30 2.75
3bp6A00 86.60 Mus musculusExternal side of plasma membraneProgrammed cell death protein 1Programmed cell death protein 1T cell receptor signaling pathway 2.60.40.10 111 15 90 2.45 2.69
1hxmB01 86.59 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 125 28 82 2.25 2.73
2ij0C00 86.42 Homo sapiensT cell receptor beta variable 20/OR9-2 2.60.40.10 118 20 85 2.35 2.75
1fo0B00 86.39 2.60.40.10 112 20 89 2.08 2.33
1hkfA00 86.13 Integral to plasma membraneNatural cytotoxicity triggering receptor 2Cellular defense responseNatural killer cell mediated cytotoxicitySignal transduction 2.60.40.10 108 11 91 2.69 2.93
1mfaH01 86.10 2.60.40.10 97 14 82 2.33 2.82
2rikA02 86.06 TitinOryctolagus cuniculus 2.60.40.10 95 14 84 2.09 2.47
1t2jA00 86.03 Homo sapiensSingle chain Fv 2.60.40.10 116 20 88 3.23 3.64
2j8hA01 85.97 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 97 13 85 2.19 2.56
1smoB00 85.86 Receptor activityTriggering receptor expressed on myeloid cells 1Homo sapiensHumoral immune response 2.60.40.10 110 17 89 2.50 2.81
1fhgA00 85.86 TelokinMeleagris gallopavo 2.60.40.10 102 14 85 2.17 2.54
2j8hA02 85.82 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 15 84 2.38 2.82
2q87C00 85.63 Homo sapiensCMRF35-like molecule 8CD300 antigen 2.60.40.10 106 12 90 4.13 4.56
1neuA00 85.54 Rattus norvegicusMyelin protein P0 2.60.40.10 115 12 86 2.57 2.96
1qfoC00 85.49 Mus musculusSialoadhesinProtein binding 2.60.40.10 114 17 89 3.96 4.43
1hxmA01 85.40 2.60.40.10 121 20 82 2.35 2.84
1xauA00 85.37 Integral to plasma membraneReceptor activityNegative regulation of B cell proliferationProtein bindingMus musculus 2.60.40.10 104 10 89 2.63 2.94
1qz1A03 85.31 Rattus norvegicusPrion diseasesNeural cell adhesion moleculePlasma membraneFibroblast growth factor receptor binding 2.60.40.10 95 13 84 2.55 3.02
1ypzF01 85.28 2.60.40.10 123 24 82 1.87 2.25
2hp4A00 85.26 T-cell surface glycoprotein CD8 alpha chainCD8A antigen, alpha polypeptideHematopoietic cell lineagePrimary immunodeficiencyHomo sapiens 2.60.40.10 112 19 89 2.54 2.84
1bihA04 85.25 Hyalophora cecropiaHemolin 2.60.40.10 88 18 76 2.31 3.01
2ny1B01 85.18 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 98 17 85 2.93 3.43
1g1cA00 85.02 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 98 13 85 2.26 2.65
3cafA01 84.98 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 96 11 80 2.40 2.98
2a38B01 84.82 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 99 10 86 2.95 3.41
1nezH00 84.79 T-cell surface glycoprotein CD8 alpha chainProtein homodimerization activityHematopoietic cell lineageCD8A antigen, alpha polypeptideT cell receptor signaling pathway 2.60.40.10 120 18 83 2.42 2.90
2rikA03 84.78 TitinOryctolagus cuniculus 2.60.40.10 92 11 84 2.37 2.81
1f97A01 84.61 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 102 14 92 3.99 4.33
1cs6A04 84.61 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 90 14 80 2.32 2.88
1gl4B00 84.58 Chondrocyte differentiationCardiac muscle tissue developmentCartilage development involved in endochondral bone morphogenesisProtein localizationBrain development 2.60.40.10 89 19 78 2.37 3.01
1dr9A01 84.38 Type I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA productionAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 105 10 84 3.55 4.19
1ncwH01 84.28 2.60.40.10 119 20 86 2.67 3.08
2v44A02 84.26 Prion diseasesNeural cell adhesion moleculePlasma membraneNeuron cell-cell adhesionNeural cell adhesion molecule 2 2.60.40.10 93 15 82 2.55 3.09
1rhfA01 84.24 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 89 15 78 3.09 3.93
2bk8A00 84.20 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 97 17 84 2.33 2.76
1eajB00 84.20 Integral to plasma membraneReceptor activityCoxsackievirus and adenovirus receptorViral myocarditisCoxsackievirus and adenovirus receptor 2.60.40.10 120 16 85 3.19 3.75
2qsqB01 84.19 Carcinoembryonic antigen-related cell adhesion molecule 5Integral to plasma membraneHomo sapiensBasolateral plasma membrane 2.60.40.10 108 15 88 3.69 4.15
1koaA03 84.16 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 96 13 84 2.20 2.60
1vcaA01 83.85 Vascular cell adhesion protein 1MicrovillusPositive regulation of T cell proliferationHeterophilic cell-cell adhesionFilopodium 2.60.40.10 89 15 80 2.82 3.50
1cczA01 83.77 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 93 10 82 3.27 3.96
2ec8A04 83.68 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 100 13 82 2.35 2.85
1bihA03 83.61 Hyalophora cecropiaHemolin 2.60.40.10 100 14 84 2.95 3.49
1cs6A01 83.55 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 105 16 83 2.76 3.29
2cqvA00 83.49 Myosin light chain kinase activityProtein phosphorylationHomo sapiensMyosin light chain kinase, smooth muscle 2.60.40.10 114 12 76 2.40 3.14
1cs6A03 83.46 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 98 18 82 2.82 3.42
1pkoA00 83.28 Rattus norvegicusMyelin-oligodendrocyte glycoproteinPositive regulation of MyD88-dependent toll-like receptor signaling pathway 2.60.40.10 123 14 78 3.08 3.91
2ec8A03 83.23 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 104 9 81 2.61 3.19
1witA00 82.69 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 93 9 83 2.66 3.19
1cs6A02 82.69 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 89 15 77 2.71 3.49
1l6zA02 82.43 Mus musculusCarcinoembryonic antigen-related cell adhesion molecule 1 2.60.40.10 96 13 82 2.75 3.33
1uctA01 82.41 Immunoglobulin alpha Fc receptorIntegral to plasma membraneCD89 antigenHomo sapiensImmune response 2.60.40.10 91 8 80 2.83 3.51
1ncnA00 82.32 T-lymphocyte activation antigen CD86Positive regulation of cell proliferationHomo sapiensImmune responseProtein binding 2.60.40.10 110 18 81 3.18 3.89
2gy5A02 82.22 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 2.60.40.10 90 16 82 2.91 3.53
1i1rA01 82.15 Jak-STAT signaling pathwayOncostatin-M receptor complexResponse to cytokine stimulusPositive regulation of osteoblast differentiationPositive regulation of tyrosine phosphorylation of Stat1 protein 2.60.40.10 100 6 82 2.44 2.96
3k3qA00 82.07 2.60.40.10 137 21 75 2.70 3.59
1iamA02 82.04 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 102 5 81 2.33 2.86
2dm2A00 81.99 NucleusHomo sapiensPalladinActin filamentMuscle alpha-actinin binding 2.60.40.10 110 11 81 2.87 3.51
1iilG02 81.98 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 107 12 79 3.36 4.23
1zxqA02 81.93 Intercellular adhesion molecule 2Integral to plasma membraneIntercellular adhesion molecule 2Natural killer cell mediated cytotoxicityHomo sapiens 2.60.40.10 107 9 81 3.04 3.74
2fcbA02 81.77 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 87 9 76 3.32 4.33
1dqtA00 81.75 Mus musculusExternal side of plasma membraneCytotoxic T-lymphocyte protein 4 2.60.40.10 117 18 84 3.32 3.92
2gy5A04 81.69 MicrovillusCell surfaceTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transductionProtein binding 2.60.40.10 99 8 81 2.75 3.37
2g5rA00 81.67 Sialic acid-binding Ig-like lectin 7Sialic acid binding Ig-like lectin 7Receptor activityIntegral to plasma membraneHomo sapiens 2.60.40.10 113 13 86 4.29 4.95
1waaC00 81.63 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 93 7 79 3.39 4.26
1itbB03 81.55 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 112 11 80 2.74 3.41
1nkrA02 81.46 Receptor activityIntegral to plasma membraneHomo sapiensImmune responseNatural killer cell inhibitory signaling pathway 2.60.40.10 98 7 81 3.05 3.74
1f2qA02 81.39 High affinity immunoglobulin epsilon receptor subunit alphaIntegral to plasma membraneHomo sapiensFc receptor, IgE, high affinity I, alpha polypeptideAsthma 2.60.40.10 90 8 77 3.77 4.85
3bfoA00 81.27 T cell receptor signaling pathwayPositive regulation of T cell cytokine productionActivation of NF-kappaB-inducing kinase activityPositive regulation of interleukin-2 productionNucleus 2.60.40.10 85 9 72 2.37 3.25
1t0pB00 80.77 Integral to plasma membraneIntercellular adhesion molecule 3Homo sapiensIntercellular adhesion molecule 3Cell adhesion molecules (CAMs) 2.60.40.10 86 10 77 3.01 3.88
1iamA01 80.53 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 83 10 77 3.34 4.30
1hzhH01 80.53 2.60.40.10 119 18 68 2.60 3.82
1rhfA02 80.44 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 84 10 77 2.67 3.44
2fcbA01 80.41 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 86 9 71 3.33 4.63
1bihA02 80.23 Hyalophora cecropiaHemolin 2.60.40.10 106 12 83 3.01 3.63
1ugnA01 80.17 Homo sapiensLeukocyte immunoglobulin-like receptor subfamily B member 1Integral to membraneResponse to virusProtein phosphatase 1 binding 2.60.40.10 95 9 82 3.83 4.64
1fltX00 80.15 Vascular endothelial growth factor receptor 1Integral to plasma membraneGrowth factor bindingVascular endothelial growth factor receptor activityFemale pregnancy 2.60.40.10 95 9 82 3.38 4.10
1q0xL02 80.09 Mus musculusIg lambda-1 chain V regionProtein binding 2.60.40.10 100 12 77 3.06 3.94
2ec8A01 80.04 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 92 10 69 3.36 4.81
1p53A01 80.00 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 98 3 80 2.98 3.70
1nkrA01 79.79 Integral to plasma membraneReceptor activityHomo sapiensNatural killer cell inhibitory signaling pathwayImmune response 2.60.40.10 97 7 82 3.83 4.64
3b4nA01 79.78 Erwinia chrysanthemiEndo-pectate lyase 2.60.40.10 88 4 78 3.20 4.07
1n26A02 79.66 Positive regulation of chemokine productionPositive regulation of smooth muscle cell proliferationJak-STAT signaling pathwayAcute-phase responsePositive regulation of osteoblast differentiation 2.60.40.10 78 16 68 3.40 4.93
1pd6A00 79.63 Myosin-binding protein C, cardiac-typeHomo sapiensVentricular cardiac muscle tissue morphogenesisStriated muscle myosin thick filamentStructural constituent of muscle 2.60.40.10 94 10 80 3.06 3.80
1v05A00 79.62 Plasma membraneFilamin-CHomo sapiens 2.60.40.10 96 6 80 3.95 4.90
1o0vA01 79.41 Homo sapiensIg epsilon chain C region 2.60.40.10 102 12 80 3.62 4.49
2nqcA00 79.37 Plasma membraneFilamin-CHomo sapiens 2.60.40.10 97 6 79 3.93 4.94
1uvqA02 79.36 2.60.40.10 99 10 77 3.31 4.26
3cmgA04 79.02 Putative beta-galactosidaseBacteroides fragilis NCTC 9343 2.60.40.1560 87 4 74 2.95 3.95
1edqA01 78.99 Chitinase ASerratia marcescens 2.60.40.10 107 5 75 3.29 4.35
2gy5A01 78.95 Cell surfaceMicrovillusIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transduction 2.60.40.10 99 4 85 3.76 4.40
3dbxA02 78.83 CD1-2 antigenGallus gallus 2.60.40.10 99 8 78 3.53 4.49
1nctA00 78.78 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 16 84 3.02 3.58
3h9yA02 78.57 Homo sapiensIg epsilon chain C region 2.60.40.10 108 6 75 3.46 4.56
1ow0A02 78.55 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 109 10 74 3.04 4.09
1mcpH02 78.29 Mus musculusIg heavy chain V region M603 2.60.40.10 99 13 76 3.61 4.71
3b9eA01 78.22 Vibrio harveyiChitinase A 2.60.40.10 110 3 73 3.25 4.41
1l6xA02 78.22 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 106 10 74 3.45 4.63
2bc4A02 78.02 HLA class II histocompatibility antigen, DM alpha chainHomo sapiensProtein binding 2.60.40.10 109 8 77 3.88 4.98
1itbB01 78.02 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 92 15 83 3.99 4.78
2nziA03 78.01 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 94 3 81 3.98 4.88
1l6xA01 78.00 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 100 9 76 3.27 4.26
1ej6A05 77.99 Mammalian orthoreovirus 3 DearingOuter capsid protein lambda-2 2.60.40.10 95 8 86 4.29 4.96
1cfbA01 77.88 Calcium ion bindingNeuron cell-cell adhesionNerve maturationDrosophila melanogasterEpidermal growth factor receptor signaling pathway 2.60.40.10 99 5 81 3.45 4.23
1hxmB02 77.83 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 105 10 78 3.44 4.40
1f00I01 77.80 Pathogenic Escherichia coli infectionIntiminIntiminProtein bindingEscherichia coli O127:H6 str. E2348/69 2.60.40.920 95 7 71 3.05 4.25
1cwvA02 77.79 InvasinYersinia pseudotuberculosis 2.60.40.920 97 3 78 3.78 4.81
1u2cA01 77.65 Epithelial tube branching involved in lung morphogenesisDilated cardiomyopathyECM-receptor interactionHypertrophic cardiomyopathy (HCM)Sarcolemma 2.60.40.10 103 9 80 3.32 4.12
3fruA02 77.57 IgG receptor FcRn large subunit p51Beta-2-microglobulin bindingRattus norvegicusHumoral immune responseIgG receptor activity 2.60.40.10 92 7 73 3.50 4.74
1ut9A01 77.56 Clostridium thermocellumCellobiohydrolase 2.60.40.10 98 2 78 3.67 4.67
1cczA02 77.54 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 78 8 71 3.48 4.84
1dr9A02 77.41 Type I diabetes mellitusIntestinal immune network for IgA productionAutoimmune thyroid diseaseAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 95 10 80 3.64 4.52
1im3D00 77.26 Unique short US2 glycoproteinHuman herpesvirus 5 strain AD169 2.60.40.1200 95 2 81 3.85 4.72
1l0qA02 77.17 Methanosarcina mazeiORF492 2.60.40.670 90 8 71 3.41 4.75
1axiB02 77.10 Jak-STAT signaling pathwayCell surfaceMulticellular organismal metabolic processGrowth hormone receptor complexInsulin-like growth factor receptor signaling pathway 2.60.40.10 101 5 75 3.76 4.97
1dn0D02 76.62 2.60.40.10 94 10 71 3.34 4.65
1y6kR01 76.49 Interleukin-10 receptor activityPlasma membraneHomo sapiensInterleukin-10 receptor subunit alpha 2.60.40.10 102 5 79 3.96 4.97
1bquA01 76.46 Oncostatin-M receptor complexJak-STAT signaling pathwayResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 100 5 83 4.07 4.87
1f6fB02 76.36 Rattus norvegicusProlactin receptorProlactin receptor activity 2.60.40.10 97 3 77 3.74 4.82
1n26A03 76.35 Positive regulation of chemokine productionJak-STAT signaling pathwayPositive regulation of smooth muscle cell proliferationResponse to cytokine stimulusAcute-phase response 2.60.40.10 104 4 77 3.79 4.87
1ujtA00 76.20 LuteolysisPositive regulation of axonogenesisCell surfaceIdentical protein bindingHomophilic cell adhesion 2.60.40.10 120 4 70 3.40 4.86
1iarB02 76.03 Jak-STAT signaling pathwayInterleukin 4 receptorIntegral to plasma membraneReceptor signaling protein activityHematopoietic cell lineage 2.60.40.10 92 6 66 2.76 4.18
1cd9B02 75.90 Mus musculusGranulocyte colony-stimulating factor receptorNeutrophil chemotaxis 2.60.40.10 98 6 80 3.83 4.75
1qg3A01 75.89 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 91 10 80 3.95 4.90
2ec8A02 75.88 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 87 9 80 3.59 4.46
1fnfA03 75.83 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 1 81 3.96 4.86
3k2mC00 75.75 2.60.40.10 101 5 81 3.89 4.77
2mcmA00 75.73 MacromomycinStreptomyces macromomyceticus 2.60.40.230 112 9 74 3.23 4.36
1qg3A02 75.72 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 104 5 83 3.92 4.69
2rb8A00 75.71 TenascinCell adhesionSyndecan bindingECM-receptor interactionTenascin 2.60.40.10 93 6 75 3.57 4.71
1k3iA03 75.50 Gibberella zeaeGalactose oxidase 2.60.40.10 97 6 79 3.97 4.99
3g08A02 75.47 Antigen-presenting glycoprotein CD1d1Endogenous lipid antigen bindingPositive thymic T cell selectionAntigen processing and presentation, exogenous lipid antigen via MHC class IbProtein binding 2.60.40.10 88 7 68 3.38 4.90
1j8kA00 75.22 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 94 4 84 4.12 4.88
1n6uA02 75.14 JAK-STAT cascadeIntegral to plasma membraneType I interferon receptor activityHomo sapiensResponse to virus 2.60.40.10 106 4 81 3.93 4.84
1gsmA02 75.07 Membrane fractionMucosal vascular addressin cell adhesion molecule 1Intestinal immune network for IgA productionCell adhesionHomo sapiens 2.60.40.10 116 6 72 2.91 4.02
3bgaA04 74.80 Galactose metabolismBacteroides thetaiotaomicronBeta-galactosidaseSphingolipid metabolismBeta-galactosidase [EC:3.2.1.23] 2.60.40.320 105 5 79 3.85 4.87
2fnbA00 74.79 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 95 7 83 4.15 4.97
1tdqA02 73.75 Nervous system developmentRattus norvegicusTenascinFocal adhesionProteinaceous extracellular matrix 2.60.40.10 90 1 84 4.07 4.82
1ok8A04 72.97 Dengue virus 2 Puerto Rico/PR159-S1/1969Genome polyprotein 2.60.40.350 100 9 82 4.04 4.90
2dtgE06 72.60 Insulin receptorInsulin receptor complexPositive regulation of nitric oxide biosynthetic processPhosphoinositide 3-kinase bindingPositive regulation of respiratory burst 2.60.40.10 103 5 83 4.13 4.95
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Displaying entries 1 to 157 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2nw2A01
QNIDQPTEMTATEGAIVQINCTYQTSGFNGLFWYQQHAGEAPTFLSYNVLDGLEEKGRFSSFLSRSKGYSYLLLKELQMK
DSASYLCAVQAGGSYIPTFGRGTSLIVHP
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2nw2A01
QNIDQPTEMTATEGAIVQINCTYQTSGFNGLFWYQQHAGEAPTFLSYNVLDGLEEKGRFSSFLSRSKGYSYLLLKELQMK
DSASYLCAVQASGGSYIPTFGRGTSLIVHP
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 11 Aug 2007 14:44

Assigning to "2.60.40.10" based on similarity with "2f54D01"

Flow stage update by auto on 11 Aug 2007 14:34

No in_process hits for Domain "2nw2A01" ready to be processed

Flow stage update by auto on 11 Aug 2007 14:34

NW result present for Domain "2nw2A01"

Flow stage update by auto on 20 Jul 2007 02:44

All required files are present for Domain "2nw2A01"

Flow stage update by auto on 18 Jul 2007 02:16

Beginning processing for Domain "2nw2A01"

Insertion by auto on 18 Jul 2007 01:33

Final ChopClose added based on similarity with "2bnqD"