CATH Classification

Domain Context

CATH Clusters

Superfamily TAZ domain
Functional Family

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q09472
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-
Transferring groups other than amino-acyl groups.
based on mapping to UniProt Q09472

UniProtKB Entries (1)

P04637
P53_HUMAN
Homo sapiens
Cellular tumor antigen p53

PDB Structure

PDB 2K8F
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation.
Feng, H., Jenkins, L.M., Durell, S.R., Hayashi, R., Mazur, S.J., Cherry, S., Tropea, J.E., Miller, M., Wlodawer, A., Appella, E., Bai, Y.
Structure