CATH Domain: 2jkhA02 XML data for domain: 2jkhA02

Molscript image for 2jkhA02
2jkhA02
PDB coordinates for domain 2jkhA02

PDB 2jkh, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.18
2.40.10.10.18.1
2.40.10.10.18.1.1
2.40.10.10.18.1.1.1
2.40.10.10.18.1.1.1.1

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Segment boundaries for domain 2jkhA02

Chopping figure for domain 2jkhA02
DomainStart PDB ResidueStop PDB Residue
2jkhA01 16 27
2jkhA01 121 232
2jkhA02 28 120
2jkhA02 233 244

Structural Neighbourhood (30 entries)

There are 30 matching structural neighberhood comparisons for CATH ID 2.40.10.10.18.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 30 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ym0A02 92.40 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 25 93 1.41 1.50
2wphS02 92.29 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 37 96 1.75 1.82
1bioA02 92.16 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 28 98 1.08 1.10
1orfA02 91.97 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 25 98 2.03 2.07
1nn6A02 91.80 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 28 96 2.29 2.38
2anyA02 90.74 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 22 93 2.19 2.34
1elvA01 90.49 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 28 86 1.80 2.08
1gvzA02 90.46 Equus caballusKallikrein-1E2 2.40.10.10 115 25 88 1.38 1.56
2asuB02 90.15 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 26 92 2.13 2.31
2hlcA01 89.90 CollagenaseHypoderma lineatum 2.40.10.10 104 29 93 3.15 3.38
1fiwA02 89.87 Ovis ariesAcrosinDrug binding 2.40.10.10 120 27 87 1.70 1.94
1q3xA03 89.52 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 25 90 1.86 2.06
3govB02 89.16 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 30 84 1.90 2.25
2r0lA02 89.15 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 22 91 1.94 2.13
2aiqA02 89.09 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 21 89 1.81 2.03
1p57B02 88.89 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 29 85 1.65 1.93
1gj7B02 88.65 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 26 88 1.62 1.82
3beuA02 88.64 Streptomyces griseusTrypsin 2.40.10.10 99 26 89 2.51 2.80
1p3cA02 85.24 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 19 90 2.66 2.93
1rrkA02 85.10 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 29 74 3.29 4.42
1agjA02 83.91 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 15 87 2.66 3.02
2pkaA00 83.39 Sus scrofaGlandular kallikrein 2.40.10.10 80 23 64 1.62 2.50
2o8lA02 83.05 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 14 80 3.13 3.87
1ky9A01 81.76 Two-component systemSerine-type endopeptidase activityProtease doResponse to temperature stimulusProtein binding 2.40.10.10 88 17 76 2.85 3.74
2qf3A01 79.85 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 102 17 71 3.44 4.82
1lcyA01 79.35 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 16 72 3.13 4.29
2z9iC01 79.24 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 91 21 67 2.52 3.73
1sotA01 79.07 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 19 71 2.98 4.19
2halA01 77.53 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 8 77 3.25 4.17
1eptA00 70.10 Sus scrofaTrypsin 2.40.10.10 43 25 29 1.02 3.45
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Displaying entries 1 to 30 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2jkhA02
PWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVL
RLKTPITFRMNVAPAFLKWIDRSMKT
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2jkhA02
PWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVL
RLKTPITFRMNVAPAFLKWIDRSMKTRGLPKAK
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 20 Jan 2009 18:33

Assigning to "2.40.10.10" based on similarity with "1hcgA02"

Flow stage update by auto on 20 Jan 2009 18:07

No in_process hits for Domain "2jkhA02" ready to be processed

Flow stage update by auto on 20 Jan 2009 18:07

NW result present for Domain "2jkhA02"

Flow stage update by auto on 20 Jan 2009 10:29

All required files are present for Domain "2jkhA02"

Flow stage update by auto on 19 Jan 2009 15:51

Beginning processing for Domain "2jkhA02"

Insertion by auto on 19 Jan 2009 14:24

Final ChopClose added based on similarity with "2bokA"