CATH Domain: 2hzcA00 XML data for domain: 2hzcA00

Molscript image for 2hzcA00
2hzcA00
PDB coordinates for domain 2hzcA00

PDB 2hzc, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.70 Alpha-Beta Plaits
3.30.70.330 Gene3D
3.30.70.330.3
3.30.70.330.3.1
3.30.70.330.3.1.1
3.30.70.330.3.1.1.1
3.30.70.330.3.1.1.1.1

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Segment boundaries for domain 2hzcA00

Chopping figure for domain 2hzcA00
DomainStart PDB ResidueStop PDB Residue
2hzcA00 143 229

Structural Neighbourhood (49 entries)

There are 49 matching structural neighberhood comparisons for CATH ID 3.30.70.330.3.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 49 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1x5uA01 87.97 SpliceosomeSpliceosomal complexHomo sapiensSplicing factor 3B subunit 4Splicing factor 3B subunit 4 3.30.70.330 80 18 82 1.75 2.11
2qfjA02 87.83 Homo sapiensPoly(U)-binding-splicing factor PUF60Protein binding 3.30.70.330 87 14 80 1.95 2.42
1cvjA01 87.73 Poly(A) RNA bindingTranslation activator activityProtein C-terminus bindingMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 77 18 80 1.77 2.20
2vooA02 87.31 TRNA modificationNucleolusMRNA bindingProtein bindingLupus La protein 3.30.70.330 89 16 85 2.04 2.39
1cvjG02 87.17 Poly(A) RNA bindingProtein C-terminus bindingTranslation activator activityMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 88 16 86 2.41 2.79
2do0A01 87.14 Protein domain specific bindingIntegral to plasma membraneParaspecklesAlternative nuclear mRNA splicing, via spliceosomeHeterogeneous nuclear ribonucleoprotein M 3.30.70.330 76 14 80 1.85 2.30
1rk8A00 87.03 SpliceosomeRNA-binding protein 8AMicrotubule cytoskeleton organizationNucleusDrosophila melanogaster 3.30.70.330 87 17 87 2.50 2.86
1fjeB01 86.57 NucleolinMesocricetus auratus 3.30.70.330 81 17 89 2.47 2.75
1h2vZ00 86.52 SpliceosomeMRNA cappingMRNA cap binding complexNuclear-transcribed mRNA catabolic process, nonsense-mediated decayNuclear cap-binding protein subunit 2 3.30.70.330 92 20 82 2.66 3.22
1fxlA02 86.33 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 77 15 78 1.82 2.33
2pehA01 86.18 Splicing factor 45SpliceosomeHomo sapiensProtein bindingSplicing factor 45 3.30.70.330 83 16 81 2.39 2.93
1nu4A00 86.12 U1 small nuclear ribonucleoprotein ASpliceosomeSpliceosomal complexHomo sapiensProtein binding 3.30.70.330 91 16 80 2.34 2.92
1x5oA01 85.98 RNA processingHomo sapiensProtein bindingRNA-binding motif, single-stranded-interacting protein 1 3.30.70.330 86 13 82 1.70 2.05
2x1fA00 85.71 Protein heterodimerization activityMRNA 3'-end-processing protein RNA15MRNA polyadenylationSaccharomyces cerevisiaeMRNA cleavage 3.30.70.330 94 24 76 2.13 2.78
1oiaA00 85.58 U1 small nuclear ribonucleoprotein ASpliceosomeSpliceosomal complexHomo sapiensProtein binding 3.30.70.330 90 14 84 3.67 4.35
3feyB00 85.33 SpliceosomeMRNA cappingMRNA cap binding complexNuclear cap-binding protein subunit 2Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3.30.70.330 97 20 78 2.67 3.41
2dgsA01 84.86 CytoplasmDAZ-associated protein 1NucleusRNA bindingHomo sapiens 3.30.70.330 89 18 84 2.44 2.90
1fxlA01 84.69 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 71 16 73 2.17 2.95
1no8A00 84.64 THO complex subunit 4Mus musculusSpliceosomeSingle-stranded DNA bindingRNA binding 3.30.70.330 78 16 80 2.22 2.76
2errA01 84.49 Fox-1 homolog AProtein C-terminus bindingHomo sapiensTrans-Golgi network 3.30.70.330 83 21 83 2.70 3.22
1uw4A00 84.35 Regulator of nonsense transcripts 3BNuclear-transcribed mRNA catabolic process, nonsense-mediated decayHomo sapiensProtein binding 3.30.70.330 90 10 78 2.63 3.33
1sjqA00 83.86 Polypyrimidine tract-binding protein 1Poly-pyrimidine tract bindingHeterogeneous nuclear ribonucleoprotein complexNucleolusMRNA processing 3.30.70.330 88 14 85 3.14 3.68
2jwnA01 83.80 CytoplasmPoly(A) RNA bindingXenopus laevisEmbryonic polyadenylate-binding protein 2-B 3.30.70.330 100 22 76 2.33 3.07
1d8zA00 83.48 Mus musculusAU-rich element bindingELAV like protein 2/3/4ELAV-like protein 3 3.30.70.330 89 11 82 2.61 3.18
1fjeB02 83.31 NucleolinMesocricetus auratus 3.30.70.330 84 21 83 2.61 3.11
2u2fA00 83.11 Splicing factor U2AF 65 kDa subunitSpliceosomeSpliceosomal complexSplicing factor U2AF 65 kDa subunitEnzyme binding 3.30.70.330 85 20 81 2.95 3.61
1jmtA00 82.77 Spliceosomal complexSplicing factor U2AF 35 kDa subunitCajal bodyHomo sapiensProtein binding 3.30.70.330 98 11 73 2.25 3.06
1hl6C00 82.08 SpliceosomeRNA-binding protein 8AMicrotubule cytoskeleton organizationNucleusDrosophila melanogaster 3.30.70.330 111 16 68 2.41 3.52
1ufwA00 82.07 Phosphatidylinositol signaling systemSynaptojanin-2Phosphatidylinositol-bisphosphatase [EC:3.1.3.36]Homo sapiensInositol phosphate metabolism 3.30.70.330 95 16 74 2.56 3.43
1vq8S00 80.83 Large subunit ribosomal protein L23Ribosome50S ribosomal protein L23PHaloarcula marismortui 3.30.70.330 81 8 71 3.23 4.53
1sjrA00 80.63 Polypyrimidine tract-binding protein 1Poly-pyrimidine tract bindingHeterogeneous nuclear ribonucleoprotein complexNucleolusMRNA processing 3.30.70.330 108 14 69 2.94 4.23
1sxlA00 80.17 Sex differentiationDrosophila melanogasterProtein complexPoly-pyrimidine tract bindingNegative regulation of translation 3.30.70.330 97 19 78 3.23 4.12
1whvA00 79.61 Mus musculusPoly(A)-specific ribonuclease PARN 3.30.70.330 100 11 69 2.98 4.32
1in0A01 78.71 Hypothetical proteinHaemophilus influenzaeUPF0234 protein HI_1034 3.30.70.860 70 8 77 3.07 3.99
2bopA00 78.20 Regulatory protein E2Bovine papillomavirus type 1 3.30.70.330 85 3 75 3.13 4.13
3sxlA02 77.86 Sex differentiationDrosophila melanogasterProtein complexPoly-pyrimidine tract bindingImaginal disc growth 3.30.70.330 55 20 56 2.07 3.68
1konA03 77.80 UPF0082 protein yebCEscherichia coli K-12 3.30.70.980 75 8 74 3.72 4.98
1wj9A01 77.68 Thermus thermophilus HB8Putative uncharacterized protein TTHB192 3.30.70.1200 87 6 81 3.59 4.40
1kohA01 77.56 Nuclear RNA export factor 1Homo sapiensProtein binding 3.30.70.330 97 6 79 3.37 4.25
1qm9A01 77.43 Polypyrimidine tract-binding protein 1Poly-pyrimidine tract bindingHeterogeneous nuclear ribonucleoprotein complexNucleolusMRNA processing 3.30.70.330 98 17 74 3.17 4.26
2rhsD06 77.12 Aminoacyl-tRNA biosynthesisStaphylococcus haemolyticus JCSC1435Phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]Phenylalanyl-tRNA synthetase beta chain 3.30.70.380 88 3 77 3.15 4.08
1fo1A01 76.93 Nuclear RNA export factor 1Homo sapiensProtein binding 3.30.70.330 55 7 58 2.27 3.87
1cvjH02 76.56 Poly(A) RNA bindingProtein C-terminus bindingMRNA polyadenylationTranslation activator activityPolyadenylate-binding protein 1 3.30.70.330 52 15 54 2.68 4.96
1yx2A02 76.53 Nitrogen metabolismAminomethyltransferase [EC:2.1.2.10]One carbon pool by folateBacillus subtilisGlycine, serine and threonine metabolism 3.30.70.1400 81 7 77 3.81 4.95
1josA00 76.45 Haemophilus influenzaeRibosome-binding factor ARibosome-binding factor A 3.30.300.20 100 6 73 3.59 4.92
2j8sA07 76.31 Hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 familyAcriflavine resistance protein BProtein bindingEscherichia coli K-12 3.30.70.1440 94 2 87 4.35 4.99
2j8sA06 75.96 Hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 familyAcriflavine resistance protein BProtein bindingEscherichia coli K-12 3.30.70.1430 105 6 69 3.32 4.78
1i1gA02 74.69 Pyrococcus furiosusHTH-type transcriptional regulator lrpALrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA 3.30.70.920 77 5 71 3.45 4.84
1ft8A01 70.98 Nuclear RNA export factor 1Homo sapiensProtein binding 3.30.70.330 55 7 52 2.41 4.56
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Displaying entries 1 to 49 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2hzcA00
GPLGSARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQ
SLKIRRP
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2hzcA00
GPLGSARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQ
SLKIRRP
BLAST against CATH

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Domain History Events (11)

Domain assigned by auto on 01 Nov 2006 18:39

Assigning to "3.30.70.330" based on similarity with "2fzrA00"

Flow stage update by auto on 01 Nov 2006 18:05

No in_process hits for Domain "2hzcA00" ready to be processed

Update comment by auto on 01 Nov 2006 14:29

Domain "2hzcA00" hits Domain "2fzrA00" (100% over 100%) which is currently in process

Update comment by auto on 01 Nov 2006 09:49

Domain "2hzcA00" hits Domain "2fzrA00" (100% over 100%) which is currently in process

Update comment by auto on 01 Nov 2006 05:50

Domain "2hzcA00" hits Domain "2fzrA00" (100% over 100%) which is currently in process

Update comment by auto on 01 Nov 2006 02:10

Domain "2hzcA00" hits Domain "2fzrA00" (100% over 100%) which is currently in process

Flow stage update by auto on 25 Oct 2006 01:36

Domain "2hzcA00" hits Domain "2fzrA00" (100% over 100%) which is currently in process

Flow stage update by auto on 25 Oct 2006 01:36

NW result present for Domain "2hzcA00"

Flow stage update by auto on 16 Oct 2006 16:34

All required files are present for Domain "2hzcA00"

Flow stage update by auto on 16 Oct 2006 03:14

Beginning processing for Domain "2hzcA00"

Insertion by auto on 16 Oct 2006 00:19

Final ChopClose added based on similarity with "1u2fA"