CATH Domain: 2hszA02

2hszA02

PDB 2hsz, Chain A, Domain 2

CATH Code	Level Description	Links
1	Mainly Alpha
1.10	Orthogonal Bundle
1.10.150	DNA polymerase; domain 1
1.10.150.240	Putative phosphatase; domain 2	Gene3D
1.10.150.240.5
1.10.150.240.5.1
1.10.150.240.5.1.1
1.10.150.240.5.1.1.1
1.10.150.240.5.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 2hszA02

Domain	Start PDB Residue	Stop PDB Residue
2hszA01	0	18
2hszA01	94	224
2hszA02	19	93

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (14 entries)

There are 14 matching structural neighberhood comparisons for CATH ID 1.10.150.240.5.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
1swvA02	86.56	Bacillus cereusPhosphonoacetaldehyde hydrolase	1.10.150.240	78	6	89	2.31	2.57
2hi0A02	86.46	Putative phosphoglycolate phosphatasePhosphoglycolate phosphatase [EC:3.1.3.18]Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842Metabolic pathwaysGlyoxylate and dicarboxylate metabolism	1.10.150.240	86	20	82	3.51	4.25
2nyvA02	85.86	Phosphoglycolate phosphatase [EC:3.1.3.18]Metabolic pathwaysGlyoxylate and dicarboxylate metabolismAquifex aeolicusPhosphoglycolate phosphatase	1.10.150.240	64	21	83	2.42	2.90
3dv9A02	84.20	Bacteroides vulgatus ATCC 8482Putative beta-phosphoglucomutase	1.10.150.240	64	9	87	2.79	3.19
2hcfA02	83.07	Chlorobaculum tepidumHydrolase, haloacid dehalogenase-like family	1.10.150.240	63	12	83	2.93	3.52
2fdrA02	82.39	Agrobacterium tumefaciens str. C58Putative uncharacterized protein	1.10.150.240	64	6	84	2.54	3.00
1te2A02	81.64	Fructose and mannose metabolismMetabolic pathwaysRiboflavin metabolismThiamine metabolismMetal ion binding	1.10.150.240	70	8	77	3.78	4.86
3ed5A02	80.67	Putative HAD-hydrolase yfnBBacillus subtilis2-haloacid dehalogenase [EC:3.8.1.2]1,2-Dichloroethane degradationGamma-Hexachlorocyclohexane degradation	1.10.150.240	79	6	77	3.19	4.13
2ah5A02	80.60	Glyoxylate and dicarboxylate metabolismMetabolic pathwaysPhosphoglycolate phosphatase [EC:3.1.3.18]Hydrolase, haloacid dehalogenase-like familyStreptococcus pneumoniae	1.10.150.240	64	7	84	2.72	3.21
2px6A02	80.58	Insulin signaling pathwayFatty acid biosynthesisFatty acid synthaseProtein bindingMetabolic pathways	1.10.1470.20	73	6	86	3.44	3.99
3b40A02	80.27	Pseudomonas aeruginosaProbable dipeptidase	1.10.287.650	58	6	73	3.66	4.97
3e58A02	79.44	Streptococcus thermophilus LMG 18311Beta-phosphoglucomutase, putative	1.10.150.240	62	3	79	2.88	3.64
1u84A00	79.16	Geobacillus kaustophilusHypothetical conserved protein	1.10.340.20	81	6	86	3.90	4.51
2qltA02	73.51	Response to osmotic stressNucleusProtein bindingMetabolic pathwaysCytoplasm	1.10.150.240	60	13	83	4.02	4.82

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Domain ATOM Sequence

>pdb|2hszA02
LPDLALSINSALKDVNLPQASENLVTWIGNGADVLSQRAVDWACKQAEKELTEDEFKYFKRQFGFYYGENLCNI

BLAST against CATH

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Domain COMBS Sequence

>pdb|2hszA02
LPDLALSINSALKDVNLPQASENLVXTWIGNGADVLSQRAVDWACKQAEKELTEDEFKYFKRQFGFYYGENLCNI

BLAST against CATH

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Domain History Events (12)

Domain assigned by auto on 11 Feb 2008 14:14

Assigning to "1.10.150.240" based on similarity with "2hszB02"