CATH Domain: 2hr2A00

2hr2A00

PDB 2hr2, Chain A, Domain 0

CATH Code	Level Description	Links
1	Mainly Alpha
1.25	Alpha Horseshoe
1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
1.25.40.10		Gene3D
1.25.40.10.11
1.25.40.10.11.1
1.25.40.10.11.1.1
1.25.40.10.11.1.1.1
1.25.40.10.11.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 2hr2A00

Domain	Start PDB Residue	Stop PDB Residue
2hr2A00	2	157

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (3 entries)

There are 3 matching structural neighberhood comparisons for CATH ID 1.25.40.10.11.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
2fo7A00	83.84		1.25.40.10	136	20	77	3.37	4.38
2v5fA00	80.88	Prolyl 4-hydroxylase subunit alpha-1Homo sapiensProcollagen-proline 4-dioxygenase activityMitochondrion	1.25.40.10	97	13	59	2.45	4.12
1na3A00	80.87		1.25.40.10	86	22	55	2.35	4.24

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Domain ATOM Sequence

>pdb|2hr2A00
KPLKEVVGAYLALSDAQRQLVAGEYDEAAANCRRAEISHTPPEEAFDHAGFDAFCHAGLAEALAGLRSFDEALHSADKAL
HYFNRRGELNQDEGKLWISAVYSRALALDGLGRGAEAPEFKKVVEIEERKGETPGKEREVAIDRIAQLGA

BLAST against CATH

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Domain COMBS Sequence

>pdb|2hr2A00
GXKPLKEVVGAYLALSDAQRQLVAGEYDEAAANCRRAXEISHTXPPEEAFDHAGFDAFCHAGLAEALAGLRSFDEALHSA
DKALHYFNRRGELNQDEGKLWISAVYSRALALDGLGRGAEAXPEFKKVVEXIEERKGETPGKERXXEVAIDRIAQLGAS

BLAST against CATH

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Domain History Events (12)

Domain assigned by auto on 14 Jan 2008 17:17

Assigning to "1.25.40.10" based on similarity with "2hr2F00"