CATH Domain: 2hj8A00 XML data for domain: 2hj8A00

Molscript image for 2hj8A00
2hj8A00
PDB coordinates for domain 2hj8A00

PDB 2hj8, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.10 Roll
3.10.20 Ubiquitin-like (UB roll)
3.10.20.90 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 Gene3D
3.10.20.90.20
3.10.20.90.20.1
3.10.20.90.20.1.1
3.10.20.90.20.1.1.2
3.10.20.90.20.1.1.2.1

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Segment boundaries for domain 2hj8A00

Chopping figure for domain 2hj8A00
DomainStart PDB ResidueStop PDB Residue
2hj8A00 86 160

Structural Neighbourhood (35 entries)

There are 35 matching structural neighberhood comparisons for CATH ID 3.10.20.90.20.1.1.2.1 (SIMAX score < 5)

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Displaying entries 1 to 35 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1wh3A01 92.33 CytoplasmDNA binding59 kDa 2'-5'-oligoadenylate synthase-like proteinThyroid hormone receptor bindingNucleolus 3.10.20.90 71 29 92 1.17 1.27
1m94A00 90.69 Ubiquitin-like protein 5Protein modification processProtein bindingNuclear mRNA splicing, via spliceosomeMating projection 3.10.20.90 73 17 94 1.61 1.70
2kd0A01 88.53 LRR repeats and ubiquitin-like domain-containing protein At2g30105Arabidopsis thaliana 3.10.20.90 71 21 92 1.43 1.55
1wx9A00 88.03 Large proline-rich protein BAT3Homo sapiensProtein binding 3.10.20.90 86 19 88 2.51 2.84
1z2mA01 87.69 RIG-I-like receptor signaling pathwayInterferon-induced 17 kDa proteinISG15-protein conjugationHomo sapiensUbiquitin cross-reactive protein 3.10.20.90 75 26 94 1.99 2.10
1p1aA00 87.58 Nucleotide excision repairUV excision repair protein RAD23 homolog BSingle-stranded DNA bindingHomo sapiensUV excision repair protein RAD23 3.10.20.90 85 18 89 1.63 1.82
1oqyA01 86.68 Nucleotide excision repairNucleotide-excision repairUV excision repair protein RAD23 homolog ASingle-stranded DNA bindingHomo sapiens 3.10.20.90 79 18 94 1.75 1.84
3ge3C00 86.53 Pseudomonas mendocinaToluene-4-monooxygenase system protein B 3.10.20.270 83 10 90 2.28 2.52
1h8cA00 86.47 Cytoplasmic sequestering of NF-kappaBHeat shock protein bindingFAS-associated factor 1CytosolPositive regulation of protein complex assembly 3.10.20.90 82 14 92 2.08 2.24
1v5oA00 85.51 Mus musculusDNA damage-inducible protein 1Protein DDI1 homolog 1 3.10.20.90 102 18 75 2.19 2.90
1uh6A00 85.16 Mus musculusUbiquitin-like protein 5Ubiquitin-like protein 5 3.10.20.90 100 12 76 1.65 2.17
1t0yA00 84.83 Caenorhabditis elegansTubulin-specific chaperone B 3.10.20.90 90 10 85 2.08 2.43
2rd0A01 84.49 Jak-STAT signaling pathwayAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.10.20.90 100 9 76 2.34 3.08
1wxmA01 84.49 Bladder cancerPathways in cancerNon-small cell lung cancerAcute myeloid leukemiaProtein binding 3.10.20.90 71 9 87 1.92 2.21
1v5tA00 84.41 Mus musculusUbiquitin-like domain-containing CTD phosphatase 1Protein phosphatase [EC:3.1.3.16] 3.10.20.90 90 25 84 3.16 3.74
1se9A00 84.30 Membrane-anchored ubiquitin-fold protein 1Arabidopsis thaliana 3.10.20.90 101 20 76 2.63 3.45
1wgdA00 84.24 Endoplasmic reticulum membraneHomo sapiensHomocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 proteinProtein binding 3.10.20.90 93 19 82 2.10 2.54
2c60A01 84.09 Neurotrophin signaling pathwayMitogen-activated protein kinase kinase kinase 3MAPKKK cascadeProtein bindingPositive regulation of I-kappaB kinase/NF-kappaB cascade 3.10.20.240 77 10 88 2.26 2.56
1wmhA00 83.06 Tight junctionInsulin signaling pathwayEndocytosisVesicle-mediated transportProtein binding 3.10.20.240 83 11 85 2.07 2.42
1k8rB00 82.63 Plasma membraneInduction of conjugation upon nitrogen starvationProtein bindingSchizosaccharomyces pombeProtein kinase byr2 3.10.20.90 82 6 74 2.27 3.05
1ip9A00 82.60 MAPK signaling pathway - yeastMating projection tipIdentical protein bindingEstablishment of cell polarityPhosphatidylinositol-3-phosphate binding 3.10.20.240 85 7 84 2.45 2.89
1v86A00 82.27 Mus musculusPutative uncharacterized protein 3.10.20.90 95 16 78 2.65 3.36
1v2yA00 82.26 U11/U12 small nuclear ribonucleoprotein 25 kDa proteinMus musculus 3.10.20.90 105 22 73 3.06 4.17
2nptB01 82.05 Mitogen-activated protein kinase kinase kinase 2Gap junctionMitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]GnRH signaling pathwayMAPK signaling pathway 3.10.20.240 81 10 86 2.52 2.92
1j8cA00 81.10 CytoplasmPlasma membraneHomo sapiensUbiquilinUbiquilin-2 3.10.20.90 103 24 72 2.01 2.76
2nptC01 81.00 Homo sapiensProtein bindingDual specificity mitogen-activated protein kinase kinase 5 3.10.20.240 88 5 77 2.40 3.11
2kfjA00 80.37 Cell division control protein 24MAPK signaling pathway - yeastMating projection tipInvasive growth in response to glucose limitationCell division control protein 24 3.10.20.240 86 6 84 3.01 3.55
1s3sH00 80.23 Rattus norvegicusGolgi organizationCellular membrane fusionNSFL1 cofactor p47Protein binding 3.10.20.90 107 15 69 1.98 2.86
1wmhB00 80.14 Partitioning defective 6 homolog alphaTranscription factor bindingViral reproductionHomo sapiens 3.10.20.240 82 9 89 2.76 3.10
1wxsA00 79.57 CytoplasmUbiquitin-fold modifier 1NucleusProtein ufmylationHomo sapiens 3.10.20.90 88 11 87 3.02 3.45
2zjdA00 78.11 Microtubule-associated protein 1 light chainHomo sapiensMicrotubule-associated proteins 1A/1B light chain 3BProtein binding 3.10.20.90 121 9 63 2.92 4.59
1y8qD03 77.27 SUMO-activating enzyme subunit 2Ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]Enzyme activator activityHomo sapiensUbiquitin mediated proteolysis 3.10.290.20 105 15 60 1.92 3.20
1oeyL00 76.96 Protein dimerization activityLeukocyte transendothelial migrationNeutrophil cytosolic factor 4CytosolNADPH oxidase complex 3.10.20.240 96 7 75 2.97 3.96
1tz1A00 75.93 Cell division control protein 24MAPK signaling pathway - yeastMating projection tipCell division control protein 24Invasive growth in response to glucose limitation 3.10.20.240 80 6 77 3.38 4.36
1i42A00 75.58 Rattus norvegicusGolgi organizationCellular membrane fusionNSFL1 cofactor p47Protein binding 3.10.20.90 89 14 83 4.00 4.81
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Displaying entries 1 to 35 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2hj8A00
DEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLR
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2hj8A00
MDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLRLRGG
LEHHHHHH
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 30 Aug 2007 15:37

Assigning to "3.10.20.90" based on similarity with "1zw7A00"

Flow stage update by auto on 30 Aug 2007 15:27

No in_process hits for Domain "2hj8A00" ready to be processed

Flow stage update by auto on 30 Aug 2007 15:26

NW result present for Domain "2hj8A00"

Flow stage update by auto on 24 Aug 2007 10:05

All required files are present for Domain "2hj8A00"

Flow stage update by auto on 23 Aug 2007 18:40

Beginning processing for Domain "2hj8A00"

Insertion by cuff on 23 Aug 2007 12:19

nice chopping