CATH Domain: 2g76A02 XML data for domain: 2g76A02

Molscript image for 2g76A02
2g76A02
PDB coordinates for domain 2g76A02

PDB 2g76, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.720 NAD(P)-binding Rossmann-like Domain Gene3D
3.40.50.720.21
3.40.50.720.21.1
3.40.50.720.21.1.1
3.40.50.720.21.1.1.1
3.40.50.720.21.1.1.1.1

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Segment boundaries for domain 2g76A02

Chopping figure for domain 2g76A02
DomainStart PDB ResidueStop PDB Residue
2g76A01 5 96
2g76A01 287 306
2g76A02 97 286

Structural Neighbourhood (35 entries)

There are 35 matching structural neighberhood comparisons for CATH ID 3.40.50.720.21.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 35 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2eklA02 91.73 D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]Sulfolobus tokodaiiGlycine, serine and threonine metabolismMetabolic pathways313aa long hypothetical D-3-phosphoglycerate dehydrogenase 3.40.50.720 191 34 97 1.64 1.68
1mx3A02 91.15 Protein domain specific bindingTranscription factor bindingProtein C-terminus bindingViral genome replicationC-terminal-binding protein 1 3.40.50.720 194 36 93 1.51 1.61
2gcgA02 90.45 Glyoxylate reductase (NADP+) [EC:1.1.1.79]Hydroxypyruvate reductase activityExcretionPyruvate metabolismNAD or NADH binding 3.40.50.720 189 32 96 1.62 1.68
2w2kA02 90.16 Rhodotorula graminisD-mandelate dehydrogenase 3.40.50.720 196 27 93 1.57 1.68
1dxyA02 90.03 Lactobacillus paracaseiD-2-hydroxyisocaproate dehydrogenase 3.40.50.720 196 28 90 1.67 1.84
1gdhA02 89.86 Glycerate dehydrogenaseHyphomicrobium methylovorum 3.40.50.720 184 27 94 1.67 1.76
2nacA02 89.78 Pseudomonas sp. 101Formate dehydrogenase 3.40.50.720 190 30 96 1.57 1.63
3k5pA02 89.68 Glycine, serine and threonine metabolismMetabolic pathwaysD-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]Brucella melitensis biovar Abortus 2308Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain:D-isomer specific 2-hydroxyacid dehydr... 3.40.50.720 180 37 90 1.91 2.10
1xdwA02 89.32 3.40.50.720 197 29 90 1.69 1.86
1qp8A02 87.91 Pyrobaculum aerophilum2-hydroxyacid dehydrogenase 3.40.50.720 179 21 92 2.00 2.16
3d4oA02 81.50 Dipicolinate synthase subunit ABacillus haloduransDipicolinate synthase subunit A 3.40.50.720 139 19 68 1.91 2.78
1li4A02 81.25 Selenoamino acid metabolismMetabolic pathwaysCysteine and methionine metabolismAdenosylhomocysteinaseAdenosylhomocysteinase [EC:3.3.1.1] 3.40.50.720 160 14 75 3.48 4.61
1pjcA02 80.61 Alanine dehydrogenasePhormidium lapideum 3.40.50.720 176 14 79 3.50 4.42
1l7eA01 80.10 Rhodospirillum rubrumNAD(P) transhydrogenase subunit alpha [EC:1.6.1.2]Nicotinate and nicotinamide metabolismMetabolic pathwaysNAD(P) transhydrogenase subunit alpha part 1 3.40.50.720 177 9 71 3.06 4.26
1o0sA04 79.79 NAD-dependent malic enzyme, mitochondrialAscaris suum 3.40.50.720 185 7 81 3.59 4.38
1o89A02 78.92 Putative quinone oxidoreductase yhdHEscherichia coli K-12 3.40.50.720 167 12 71 3.16 4.43
3d6nB02 78.88 Pyrimidine metabolismAspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]Aspartate carbamoyltransferaseAlanine, aspartate and glutamate metabolismMetabolic pathways 3.40.50.1370 144 13 64 2.54 3.91
1yqdA02 77.86 Sinapyl alcohol dehydrogenasePopulus tremuloides 3.40.50.720 157 15 68 3.07 4.47
1ml4A02 77.73 Pyrimidine metabolismAspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]Pyrococcus abyssiAspartate carbamoyltransferaseAlanine, aspartate and glutamate metabolism 3.40.50.1370 158 13 70 3.01 4.29
1h2bA02 77.72 Tyrosine metabolismFatty acid metabolism1- and 2-Methylnaphthalene degradationMetabolic pathwaysAeropyrum pernix 3.40.50.720 140 10 67 2.75 4.10
1v3uB02 77.45 Cavia porcellusProstaglandin reductase 1 3.40.50.720 178 12 70 3.40 4.81
1lluA02 77.37 Tyrosine metabolismFatty acid metabolism1- and 2-Methylnaphthalene degradationMetabolic pathwaysMetabolism of xenobiotics by cytochrome P450 3.40.50.720 138 10 67 3.06 4.53
1vi2A02 77.29 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysQuinate/shikimate dehydrogenaseQuinate/shikimate dehydrogenase [EC:1.1.1.282]Shikimate 5-dehydrogenase activity 3.40.50.720 147 14 67 3.27 4.84
1vj0A02 77.21 Butanoate metabolismThermotoga maritima[EC:1.1.1.-]Alcohol dehydrogenase, zinc-containingFructose and mannose metabolism 3.40.50.720 147 14 68 3.02 4.44
3grfA02 76.91 Arginine and proline metabolismGiardia intestinalisOrnithine carbamoyltransferaseOrnithine carbamoyltransferase [EC:2.1.3.3]Metabolic pathways 3.40.50.1370 165 8 72 3.53 4.84
1nytA02 76.69 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysShikimate 5-dehydrogenase [EC:1.1.1.25]Shikimate dehydrogenaseProtein binding 3.40.50.720 143 13 68 3.32 4.84
1piwA02 76.66 NADP-dependent alcohol dehydrogenase 6Alcohol dehydrogenase (NADP+) activityAlcohol metabolic processHydroxymethylfurfural reductase (NADH) activitySoluble fraction 3.40.50.720 137 16 65 2.92 4.43
1bgvA01 76.51 NAD-specific glutamate dehydrogenaseClostridium symbiosum 3.40.50.720 167 8 70 3.50 4.98
1duvG02 76.34 Arginine and proline metabolismMetabolic pathwaysOrnithine carbamoyltransferase activityOrnithine carbamoyltransferase [EC:2.1.3.3]Ornithine carbamoyltransferase chain I 3.40.50.1370 183 8 70 3.32 4.73
1pl8A02 76.24 Membrane fractionZinc ion bindingL-iditol 2-dehydrogenase [EC:1.1.1.14]Sorbitol catabolic processGlucose metabolic process 3.40.50.720 139 10 65 3.08 4.71
2o3jA03 76.09 Caenorhabditis elegansAmino sugar and nucleotide sugar metabolismIdentical protein bindingEmbryo development ending in birth or egg hatchingMetabolic pathways 3.40.50.720 215 9 62 3.11 4.95
2zb4A02 75.78 Homo sapiensProstaglandin reductase 2 3.40.50.720 181 8 71 3.28 4.57
1iz0A02 75.78 NADPH2:quinone reductase [EC:1.6.5.5]Probable quinone oxidoreductaseThermus thermophilus 3.40.50.720 152 9 63 2.64 4.17
1npyA02 74.49 Shikimate 5-dehydrogenase [EC:1.1.1.25]Haemophilus influenzaePhenylalanine, tyrosine and tryptophan biosynthesisShikimate 5-dehydrogenase-like protein HI_0607Metabolic pathways 3.40.50.720 169 7 70 3.10 4.42
1ur5C01 73.93 Malate dehydrogenase [EC:1.1.1.37]Citrate cycle (TCA cycle)Pyruvate metabolismChloroflexus aurantiacus J-10-flMetabolic pathways 3.40.50.720 136 8 57 2.75 4.74
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Displaying entries 1 to 35 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2g76A02
TPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPI
ISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGA
ALDVFTEEPPRDRALVDHENVISCPHLGAS
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2g76A02
TPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPI
ISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGA
ALDVFTEEPPRDRALVDHENVISCPHLGAS
BLAST against CATH

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Domain History Events (8)

Domain assigned by auto on 27 Apr 2009 14:26

Assigning to "3.40.50.720" based on similarity with "2g76B02"

Flow stage update by auto on 27 Apr 2009 14:23

No in_process hits for Domain "2g76A02" ready to be processed

Update comment by auto on 27 Apr 2009 11:23

Domain "2g76A02" hits Domain "2g76B02" (100% over 100%) which is currently in process

Flow stage update by auto on 27 Apr 2009 11:08

Domain "2g76A02" hits Domain "2g76B02" (100% over 100%) which is currently in process

Flow stage update by auto on 27 Apr 2009 11:08

NW result present for Domain "2g76A02"

Flow stage update by auto on 25 Apr 2009 08:08

All required files are present for Domain "2g76A02"

Flow stage update by auto on 24 Apr 2009 02:31

Beginning processing for Domain "2g76A02"

Insertion by auto on 23 Apr 2009 20:34

Final ChopClose added based on similarity with "2g76B"