CATH Domain: 2fnaA02

2fnaA02

PDB 2fna, Chain A, Domain 2

CATH Code	Level Description	Links
1	Mainly Alpha
1.10	Orthogonal Bundle
1.10.8	Helicase, Ruva Protein; domain 3
1.10.8.60		Gene3D
1.10.8.60.5
1.10.8.60.5.1
1.10.8.60.5.1.1
1.10.8.60.5.1.1.1
1.10.8.60.5.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 2fnaA02

Domain	Start PDB Residue	Stop PDB Residue
2fnaA01	0	207
2fnaA02	208	283
2fnaA03	284	356

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (15 entries)

There are 15 matching structural neighberhood comparisons for CATH ID 1.10.8.60.5.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
2chgA02	83.30	Archaeoglobus fulgidusReplication factor C small subunitReplication factor C small subunit	1.10.8.60	66	9	77	2.08	2.70
1sxjC02	82.40	Nucleotide excision repairDNA replicationLeading strand elongationReplication factor C subunit 3Replication factor C subunit 3/5	1.10.8.60	69	5	78	2.52	3.22
1jr3D03	82.34	Pyrimidine metabolismDNA replicationPurine metabolismMetabolic pathwaysHomologous recombination	1.10.8.60	71	5	78	2.52	3.22
1sxjE02	81.27	Leading strand elongationNucleotide excision repairDNA replicationReplication factor C subunit 3/5Sister chromatid cohesion	1.10.8.60	64	9	72	2.12	2.91
3bosA02	81.03	DnaA-homolog proteinShewanella amazonensis SB2BRegulatory inactivation of DnaA Hda protein	1.10.8.60	59	6	68	2.23	3.24
2z4sA02	80.00	Thermotoga maritimaTwo-component systemChromosomal replication initiator proteinChromosomal replication initiator protein dnaA	1.10.8.60	72	9	81	3.93	4.85
1njgA02	79.77	Pyrimidine metabolismDNA replicationPurine metabolismMetabolic pathwaysHomologous recombination	1.10.8.60	66	6	79	3.61	4.53
1nvmA02	79.17	Pseudomonas sp. CF6004-hydroxy-2-oxovalerate aldolase	1.10.8.60	64	6	75	3.75	4.96
1e32A04	78.85	Mus musculusPolyubiquitin bindingProtein complexAggresome assemblyTransitional endoplasmic reticulum ATPase	1.10.8.60	87	10	67	3.05	4.50
1sxjD02	78.26	DNA replicationNucleotide excision repairLeading strand elongationCell cycle checkpointProtein binding	1.10.8.60	70	11	74	2.76	3.71
1r7rA06	78.04	Mus musculusPolyubiquitin bindingProtein complexAggresome assemblyTransitional endoplasmic reticulum ATPase	1.10.8.60	58	1	72	3.27	4.48
1fnnA01	78.02	Pyrobaculum aerophilumCell division control protein 6 (Cdc6), putativeArchaeal cell division control protein 6	1.10.8.60	101	4	57	2.22	3.87
1njgB01	76.24	Pyrimidine metabolismDNA replicationPurine metabolismMetabolic pathwaysHomologous recombination	1.10.8.60	73	8	77	3.62	4.70
3bg5B07	72.04	Citrate cycle (TCA cycle)Pyruvate metabolismMetabolic pathwaysPyruvate carboxylase subunit A [EC:6.4.1.1]Pyruvate carboxylase subunit B [EC:6.4.1.1]	1.10.10.60	46	10	55	2.62	4.73
3bg3B04	71.18	Pyruvate carboxylase subunit A [EC:6.4.1.1]Citrate cycle (TCA cycle)Biotin bindingPyruvate metabolismPyruvate carboxylase, mitochondrial	1.10.10.60	44	6	58	2.78	4.78

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Domain ATOM Sequence

>pdb|2fnaA02
FSREEAIEFLRRGFQEADIDFKDYEVVYEKIGGIPGWLTYFGFIYLDNKNLDFAINQTLEYAKKLILKEFENFLHG

BLAST against CATH

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Domain COMBS Sequence

>pdb|2fnaA02
FSREEAIEFLRRGFQEADIDFKDYEVVYEKIGGIPGWLTYFGFIYLDNKNLDFAINQTLEYAKKLILKEFENFLHG

BLAST against CATH

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Domain History Events (12)

Domain assigned by auto on 07 Feb 2008 14:22

Assigning to "1.10.8.60" based on similarity with "2fnaB02"