CATH Domain: 2f91A02 XML data for domain: 2f91A02

Molscript image for 2f91A02
2f91A02
PDB coordinates for domain 2f91A02

PDB 2f91, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.7
2.40.10.10.7.1
2.40.10.10.7.1.1
2.40.10.10.7.1.1.1
2.40.10.10.7.1.1.1.1

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Segment boundaries for domain 2f91A02

Chopping figure for domain 2f91A02
DomainStart PDB ResidueStop PDB Residue
2f91A01 16 27
2f91A01 121 233
2f91A02 28 120
2f91A02 234 244

Structural Neighbourhood (38 entries)

There are 38 matching structural neighberhood comparisons for CATH ID 2.40.10.10.7.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 38 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ym0A02 93.50 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 34 95 0.93 0.97
1hj9A02 92.81 Neuroactive ligand-receptor interactionBos taurusCationic trypsinTrypsin [EC:3.4.21.4]Protein binding 2.40.10.10 103 41 89 1.11 1.24
2wphS02 92.71 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 37 91 1.40 1.52
2jkhA02 92.43 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 32 92 1.56 1.68
1hj8A02 92.16 Salmo salarTrypsin-1 2.40.10.10 103 40 89 1.26 1.41
1eaxA02 92.12 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 115 32 94 1.91 2.02
1a7sA02 91.11 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 26 89 1.32 1.48
1nn6A02 91.07 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 25 92 2.42 2.61
1bioA02 91.04 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 27 93 1.71 1.82
2anyA02 91.02 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 27 96 2.31 2.40
2bvrH02 90.67 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 116 26 92 1.34 1.45
1gvzA02 90.67 Equus caballusKallikrein-1E2 2.40.10.10 115 25 87 1.40 1.59
3gylB02 90.51 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 111 24 92 1.16 1.25
1orfA02 90.49 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 22 91 1.77 1.94
1fiwA02 90.23 Ovis ariesAcrosinDrug binding 2.40.10.10 120 25 91 1.88 2.05
2qxiA02 90.08 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 23 83 1.52 1.81
3govB02 90.01 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 28 87 1.92 2.19
2asuB02 89.55 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 31 90 1.74 1.93
2r0lA02 89.41 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 20 92 1.91 2.06
1p57B02 89.30 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 23 88 1.80 2.04
1gj7B02 89.23 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 21 93 1.63 1.75
2hlcA01 88.67 CollagenaseHypoderma lineatum 2.40.10.10 104 25 89 3.68 4.12
3beuA02 88.66 Streptomyces griseusTrypsin 2.40.10.10 99 21 85 1.73 2.02
2aiqA02 88.63 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 18 88 2.11 2.38
1elvA01 88.54 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 25 81 1.69 2.08
1q3xA03 88.36 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 26 88 2.11 2.39
1rrkA02 85.54 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 18 77 3.14 4.04
1p3cA02 84.40 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 13 90 3.75 4.16
1agjA02 83.93 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 13 87 2.52 2.88
2pkaA00 82.81 Sus scrofaGlandular kallikrein 2.40.10.10 80 21 60 1.76 2.90
2o8lA02 82.72 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 12 81 3.34 4.11
1ky9A01 81.22 Two-component systemSerine-type endopeptidase activityProtease doResponse to temperature stimulusProtein binding 2.40.10.10 88 10 70 2.37 3.36
1sotA01 80.27 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 8 72 2.81 3.86
2qf3A01 79.88 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 102 8 69 3.31 4.75
1lcyA01 79.64 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 7 74 2.85 3.85
2z9iC01 79.02 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 91 9 66 3.31 4.94
2hntC00 74.93 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 67 17 43 1.27 2.90
1eptA00 68.89 Sus scrofaTrypsin 2.40.10.10 43 30 27 1.20 4.34
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Displaying entries 1 to 38 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2f91A02
PYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQIVAGELDMSVNEGSEQIITVSKIILHENFDYNL
LDNDISLLKLSGSLTFNDNVAPYHVDWIKANAV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2f91A02
PYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQIVAGELDMSVNEGSEQIITVSKIILHENFDYNL
LDNDISLLKLSGSLTFNDNVAPYHVDWIKANAV
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 25 Jul 2007 10:43

Assigning to "2.40.10.10" based on similarity with "1yr4A02"

Flow stage update by auto on 25 Jul 2007 10:40

No in_process hits for Domain "2f91A02" ready to be processed

Flow stage update by auto on 25 Jul 2007 10:40

NW result present for Domain "2f91A02"

Flow stage update by auto on 16 Jul 2007 22:38

All required files are present for Domain "2f91A02"

Flow stage update by auto on 14 Jul 2007 23:03

Beginning processing for Domain "2f91A02"

Insertion by auto on 14 Jul 2007 22:13

Final ChopClose added based on similarity with "1yr4A"