CATH Domain: 2f48A03

2f48A03

PDB 2f48, Chain A, Domain 3

CATH Code	Level Description	Links
1	Mainly Alpha
1.10	Orthogonal Bundle
1.10.10	Arc Repressor Mutant, subunit A
1.10.10.480	Phosphofructokinase; domain 3	Gene3D
1.10.10.480.1
1.10.10.480.1.1
1.10.10.480.1.1.1
1.10.10.480.1.1.1.1
1.10.10.480.1.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 2f48A03

Domain	Start PDB Residue	Stop PDB Residue
2f48A01	5	219
2f48A01	432	501
2f48A02	220	317
2f48A02	393	431
2f48A02	502	552
2f48A03	318	392

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (3 entries)

There are 3 matching structural neighberhood comparisons for CATH ID 1.10.10.480.1.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
1nklA00	79.14	Sus scrofaAntimicrobial peptide NK-lysin	1.10.225.10	78	9	88	3.90	4.41
2gtgA00	78.11	Proactivator polypeptideLipid transportGlycosphingolipid metabolic processEnzyme activator activityIntegral to membrane	1.10.225.10	78	8	83	3.91	4.69
1l9lA00	77.55	GranulysinHomo sapiensCellular defense responseExtracellular space	1.10.225.10	74	8	89	4.30	4.81

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Domain ATOM Sequence

>pdb|2f48A03
IPEVKSLMLELCDIFDKNEGEFKGLNIEKMKEIFVAKLSDYMKGVYLSLPLFIQFELIKSILERDPHGNFNVSRV

BLAST against CATH

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Domain COMBS Sequence

>pdb|2f48A03
IPEVKSLMLELCDIFDKNEGEFKGLNIEKMKEIFVAKLSDYMKGVYLSLPLFIQFELIKSILERDPHGNFNVSRV

BLAST against CATH

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Domain History Events (11)

Domain assigned by auto on 11 Mar 2009 21:12

Assigning to "1.10.10.480" based on similarity with "1kzhA03"