CATH Domain: 2f46A00 XML data for domain: 2f46A00

Molscript image for 2f46A00
2f46A00
PDB coordinates for domain 2f46A00

PDB 2f46, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.90 Alpha-Beta Complex
3.90.190 Protein-Tyrosine Phosphatase; Chain A
3.90.190.10 Protein tyrosine phosphatase superfamily Gene3D
3.90.190.10.14
3.90.190.10.14.1
3.90.190.10.14.1.1
3.90.190.10.14.1.1.1
3.90.190.10.14.1.1.1.1

Segment boundaries for domain 2f46A00

Chopping figure for domain 2f46A00
DomainStart PDB ResidueStop PDB Residue
2f46A00 13 155

Structural Neighbourhood (12 entries)

There are 12 matching structural neighberhood comparisons for CATH ID 3.90.190.10.14.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 12 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1zzwA00 83.24 Dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]NucleusCytoplasmProtein dephosphorylationDual specificity protein phosphatase 10 3.90.190.10 147 11 85 3.18 3.71
2imgA00 82.46 Homo sapiensDual specificity protein phosphatase 23 3.90.190.10 148 8 85 2.99 3.51
1oheA02 82.05 Protein serine/threonine phosphatase activityProtein tyrosine phosphatase activityHomo sapiensProtein bindingDual specificity protein phosphatase CDC14B 3.90.190.10 169 10 75 2.65 3.50
2g6zA00 82.00 Protein dephosphorylationDual specificity phosphatase [EC:3.1.3.16 3.1.3.48]MAPK signaling pathwayProtein tyrosine phosphatase activityHomo sapiens 3.90.190.10 147 12 84 3.21 3.81
1xriA00 80.73 Probable tyrosine-protein phosphatase At1g05000Arabidopsis thaliana 3.90.190.10 148 12 86 3.43 3.97
1rxdB00 79.88 Protein tyrosine phosphatase type IVA 1Homo sapiensProtein-tyrosine phosphatase [EC:3.1.3.48] 3.90.190.10 149 10 85 3.29 3.86
1fpzC00 79.69 Protein tyrosine/serine/threonine phosphatase activityCell cycle arrestRegulation of cyclin-dependent protein kinase activityProtein bindingPerinuclear region of cytoplasm 3.90.190.10 178 14 76 2.60 3.40
2hcmA01 79.43 Mus musculusDual specificity phosphatase 28 3.90.190.10 143 10 85 3.99 4.68
2r0bA00 78.90 Homo sapiensSerine/threonine/tyrosine-interacting protein 3.90.190.10 148 13 87 3.80 4.33
1oheA01 77.31 Protein serine/threonine phosphatase activityProtein tyrosine phosphatase activityHomo sapiensProtein bindingDual specificity protein phosphatase CDC14B 3.90.190.10 149 7 70 3.17 4.50
1d5rA01 76.77 Tight junctionGliomaFocal adhesionP53 signaling pathwayPhosphatidylinositol signaling system 3.90.190.10 174 7 72 3.44 4.75
1w78A02 73.67 Folate biosynthesisMetabolic pathwaysTetrahydrofolylpolyglutamate synthase activityProtein bindingEscherichia coli K-12 3.90.190.20 132 8 75 3.79 4.99
Displaying entries 1 to 12 (page 1 of 1)


Domain ATOM Sequence

>pdb|2f46A00
KAILKLDEHLYISPQLTKADAEQIAQLGIKTIICNRPDREEESQPDFAQIKQWLEQAGVTGFHHQPVTARDIQKHDVETF
RQLIGQAEYPVLAYCRTGTRCSLLWGFRRAAEGPVDEIIRRAQAAGVNLENFRERLDNARV    

Domain COMBS Sequence

>pdb|2f46A00
GXPSEKQPQSKGNKXAILKLDEHLYISPQLTKADAEQIAQLGIKTIICNRPDREEESQPDFAQIKQWLEQAGVTGFHHQP
VTARDIQKHDVETFRQLIGQAEYPVLAYCRTGTRCSLLWGFRRAAEGXPVDEIIRRAQAAGVNLENFRERLDNARV    

Domain History Events (10)

Domain assigned by auto on 13 Nov 2007 18:15

Assigning to "3.90.190.10" based on similarity with "2f46B00"

Flow stage update by auto on 13 Nov 2007 18:06

No in_process hits for Domain "2f46A00" ready to be processed

Update comment by auto on 03 Sep 2007 20:09

Domain "2f46A00" hits Domain "2f46B00" (98.0769230769231% over 100%) which is currently in process

Update comment by auto on 03 Sep 2007 11:15

Domain "2f46A00" hits Domain "2f46B00" (98.0769230769231% over 100%) which is currently in process

Update comment by auto on 26 Aug 2007 18:10

Domain "2f46A00" hits Domain "2f46B00" (98.0769230769231% over 100%) which is currently in process

Flow stage update by auto on 26 Aug 2007 18:09

Domain "2f46A00" hits Domain "2f46B00" (98.0769230769231% over 100%) which is currently in process

Flow stage update by auto on 26 Aug 2007 18:09

NW result present for Domain "2f46A00"

Flow stage update by auto on 19 Aug 2007 10:12

All required files are present for Domain "2f46A00"

Flow stage update by auto on 18 Aug 2007 14:31

Beginning processing for Domain "2f46A00"

Insertion by auto on 18 Aug 2007 14:03

Final ChopClose added based on similarity with "2f46B"