CATH Domain: 2eklA02 XML data for domain: 2eklA02

Molscript image for 2eklA02
2eklA02
PDB coordinates for domain 2eklA02

PDB 2ekl, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.720 NAD(P)-binding Rossmann-like Domain Gene3D
3.40.50.720.27
3.40.50.720.27.1
3.40.50.720.27.1.1
3.40.50.720.27.1.1.1
3.40.50.720.27.1.1.1.1

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Segment boundaries for domain 2eklA02

Chopping figure for domain 2eklA02
DomainStart PDB ResidueStop PDB Residue
2eklA01 2 96
2eklA01 288 313
2eklA02 97 287

Structural Neighbourhood (35 entries)

There are 35 matching structural neighberhood comparisons for CATH ID 3.40.50.720.27.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 35 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1dxyA02 90.61 Lactobacillus paracaseiD-2-hydroxyisocaproate dehydrogenase 3.40.50.720 196 29 92 2.16 2.33
2gcgA02 90.34 Glyoxylate reductase (NADP+) [EC:1.1.1.79]Hydroxypyruvate reductase activityExcretionPyruvate metabolismNAD or NADH binding 3.40.50.720 189 26 95 2.13 2.22
1mx3A02 90.33 Protein domain specific bindingTranscription factor bindingProtein C-terminus bindingViral genome replicationC-terminal-binding protein 1 3.40.50.720 194 25 94 2.32 2.45
1xdwA02 89.94 3.40.50.720 197 27 92 1.94 2.10
1gdhA02 89.74 Glycerate dehydrogenaseHyphomicrobium methylovorum 3.40.50.720 184 21 92 1.85 2.00
2nacA02 89.58 Pseudomonas sp. 101Formate dehydrogenase 3.40.50.720 190 20 96 2.07 2.15
3k5pA02 88.89 Glycine, serine and threonine metabolismMetabolic pathwaysD-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]Brucella melitensis biovar Abortus 2308Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain:D-isomer specific 2-hydroxyacid dehydr... 3.40.50.720 180 37 91 3.32 3.64
1qp8A02 87.85 Pyrobaculum aerophilum2-hydroxyacid dehydrogenase 3.40.50.720 179 21 92 2.77 2.99
1li4A02 81.86 Selenoamino acid metabolismMetabolic pathwaysCysteine and methionine metabolismAdenosylhomocysteinaseAdenosylhomocysteinase [EC:3.3.1.1] 3.40.50.720 160 16 74 3.32 4.43
3d4oA02 81.53 Dipicolinate synthase subunit ABacillus haloduransDipicolinate synthase subunit A 3.40.50.720 139 12 67 1.95 2.89
1l7eA01 81.16 Rhodospirillum rubrumNAD(P) transhydrogenase subunit alpha [EC:1.6.1.2]Nicotinate and nicotinamide metabolismMetabolic pathwaysNAD(P) transhydrogenase subunit alpha part 1 3.40.50.720 177 11 71 3.21 4.48
1pjcA02 80.93 Alanine dehydrogenasePhormidium lapideum 3.40.50.720 176 14 78 3.90 5.00
1o0sA04 80.16 NAD-dependent malic enzyme, mitochondrialAscaris suum 3.40.50.720 185 9 79 3.51 4.41
1o89A02 78.70 Putative quinone oxidoreductase yhdHEscherichia coli K-12 3.40.50.720 167 9 70 3.31 4.68
1ml4A02 78.54 Pyrimidine metabolismAspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]Pyrococcus abyssiAspartate carbamoyltransferaseAlanine, aspartate and glutamate metabolism 3.40.50.1370 158 10 70 3.36 4.79
1lluA02 78.39 Tyrosine metabolismFatty acid metabolism1- and 2-Methylnaphthalene degradationMetabolic pathwaysMetabolism of xenobiotics by cytochrome P450 3.40.50.720 138 16 65 2.76 4.22
1vi2A02 78.12 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysQuinate/shikimate dehydrogenaseQuinate/shikimate dehydrogenase [EC:1.1.1.282]Shikimate 5-dehydrogenase activity 3.40.50.720 147 12 67 2.93 4.37
3d6nB02 78.06 Pyrimidine metabolismAspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]Aspartate carbamoyltransferaseAlanine, aspartate and glutamate metabolismMetabolic pathways 3.40.50.1370 144 10 64 3.09 4.80
1nytA02 78.00 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysShikimate 5-dehydrogenase [EC:1.1.1.25]Shikimate dehydrogenaseProtein binding 3.40.50.720 143 11 69 3.07 4.44
1yqdA02 77.92 Sinapyl alcohol dehydrogenasePopulus tremuloides 3.40.50.720 157 17 67 2.99 4.43
1h2bA02 77.91 Tyrosine metabolismFatty acid metabolism1- and 2-Methylnaphthalene degradationMetabolic pathwaysAeropyrum pernix 3.40.50.720 140 11 66 2.71 4.08
2eggA02 77.81 Shikimate 5-dehydrogenase [EC:1.1.1.25]Geobacillus kaustophilusPhenylalanine, tyrosine and tryptophan biosynthesisShikimate 5-dehydrogenaseMetabolic pathways 3.40.50.720 140 12 65 2.53 3.84
1v3uB02 77.78 Cavia porcellusProstaglandin reductase 1 3.40.50.720 178 14 68 3.37 4.91
1vj0A02 77.65 Butanoate metabolismThermotoga maritima[EC:1.1.1.-]Alcohol dehydrogenase, zinc-containingFructose and mannose metabolism 3.40.50.720 147 14 67 2.96 4.42
1bgvA01 77.05 NAD-specific glutamate dehydrogenaseClostridium symbiosum 3.40.50.720 167 13 69 3.26 4.68
1pl8A02 76.99 Membrane fractionZinc ion bindingL-iditol 2-dehydrogenase [EC:1.1.1.14]Sorbitol catabolic processGlucose metabolic process 3.40.50.720 139 12 64 2.97 4.61
1wlyA02 76.16 2-haloacrylate reductaseBurkholderia sp. WS 3.40.50.720 147 10 68 3.09 4.54
1npyA02 76.10 Shikimate 5-dehydrogenase [EC:1.1.1.25]Haemophilus influenzaePhenylalanine, tyrosine and tryptophan biosynthesisShikimate 5-dehydrogenase-like protein HI_0607Metabolic pathways 3.40.50.720 169 7 69 2.88 4.17
1pqwA00 75.45 PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSCPhenolpthiocerol synthesis type-I polyketide synthase CMycobacterium tuberculosis 3.40.50.720 183 8 72 3.32 4.60
1ur5C01 75.39 Malate dehydrogenase [EC:1.1.1.37]Citrate cycle (TCA cycle)Pyruvate metabolismChloroflexus aurantiacus J-10-flMetabolic pathways 3.40.50.720 136 14 58 2.58 4.44
1t2dA01 74.98 L-lactate dehydrogenaseCysteine and methionine metabolismGlycolysis / GluconeogenesisPyruvate metabolismPlasmodium falciparum CDC/Honduras 3.40.50.720 148 12 58 2.80 4.82
1y7tA01 74.53 Citrate cycle (TCA cycle)Pyruvate metabolismGlyoxylate and dicarboxylate metabolismMetabolic pathwaysMalate dehydrogenase [EC:1.1.1.37] 3.40.50.720 153 9 59 2.63 4.45
1o6zA02 74.48 Malate dehydrogenase [EC:1.1.1.37]Citrate cycle (TCA cycle)Pyruvate metabolismHaloarcula marismortuiMetabolic pathways 3.40.50.720 142 16 56 2.70 4.82
1hyhA01 73.87 Weissella confusaL-2-hydroxyisocaproate dehydrogenase 3.40.50.720 141 11 57 2.80 4.86
1hyeA01 73.09 Malate dehydrogenase [EC:1.1.1.37]Citrate cycle (TCA cycle)Methanocaldococcus jannaschiiPyruvate metabolismMetabolic pathways 3.40.50.720 147 10 57 2.83 4.96
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Displaying entries 1 to 35 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2eklA02
APGASTDSAVELTIGLMIAAARKMYTSMALAKSGIFKKIEGLELAGKTIGIVGFGRIGTKVGIIANAMGMKVLAYDILDI
REKAEKINAKAVSLEELLKNSDVISLHVTVSKDAKPIIDYPQFELMKDNVIIVNTSRAVAVNGKALLDYIKKGKVYAYAT
DVFWNEPPKEEWELELLKHERVIVTTHIGAQ
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2eklA02
APGASTDSAVELTIGLMIAAARKMYTSMALAKSGIFKKIEGLELAGKTIGIVGFGRIGTKVGIIANAMGMKVLAYDILDI
REKAEKINAKAVSLEELLKNSDVISLHVTVSKDAKPIIDYPQFELMKDNVIIVNTSRAVAVNGKALLDYIKKGKVYAYAT
DVFWNEPPKEEWELELLKHERVIVTTHIGAQ
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 27 Apr 2009 11:27

Assigning to "3.40.50.720" based on similarity with "1wwkA02"

Flow stage update by auto on 27 Apr 2009 11:08

No in_process hits for Domain "2eklA02" ready to be processed

Flow stage update by auto on 27 Apr 2009 11:08

NW result present for Domain "2eklA02"

Flow stage update by auto on 25 Apr 2009 08:08

All required files are present for Domain "2eklA02"

Flow stage update by auto on 24 Apr 2009 02:31

Beginning processing for Domain "2eklA02"

Insertion by auto on 23 Apr 2009 20:57

Final ChopClose added based on similarity with "1wwkA"