CATH Domain: 2e42A00 XML data for domain: 2e42A00

Molscript image for 2e42A00
2e42A00
PDB coordinates for domain 2e42A00

PDB 2e42, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.170 Gene3D
1.20.5.170.6
1.20.5.170.6.1
1.20.5.170.6.1.1
1.20.5.170.6.1.1.1
1.20.5.170.6.1.1.1.1

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Segment boundaries for domain 2e42A00

Chopping figure for domain 2e42A00
DomainStart PDB ResidueStop PDB Residue
2e42A00 268 332

Structural Neighbourhood (64 entries)

There are 64 matching structural neighberhood comparisons for CATH ID 1.20.5.170.6.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 64 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1gu4A00 97.68 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 98 100 0.29 0.29
1l2pA00 89.42 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 11 84 1.48 1.75
1pl5A00 88.86 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 7 86 2.07 2.39
1nwqA00 88.04 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 75 92 2.55 2.76
1ci6A00 87.91 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 14 86 1.82 2.11
1ic2B00 87.69 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 16 84 2.29 2.71
1gk4C00 86.69 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 9 91 2.61 2.85
3e7kA00 86.55 Rattus norvegicusCalcium channel activityCalcium ion transportIntegral to membraneProtein binding 1.20.5.1010 54 1 83 1.97 2.37
1jcdB00 86.40 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 5 80 1.92 2.40
1ezjA02 86.20 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 17 75 1.23 1.63
3gwoA00 85.92 Human immunodeficiency virus type 1 lw12.3 isolateEnvelope glycoprotein gp160 1.10.287.210 53 11 81 1.96 2.40
3ii6A02 85.84 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 5 86 2.87 3.33
1gd2F00 85.49 NuA4 histone acetyltransferase complexFungal AP-1-like factorResponse to hydrogen peroxideResponse to methylglyoxalCellular response to oxidative stress 1.20.5.170 64 15 92 4.43 4.80
1ci6B00 85.26 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 95 69 1.46 2.11
2b9bA04 84.94 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 8 92 4.09 4.43
1a02F00 84.89 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 7 72 1.96 2.71
1uixA00 84.66 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 9 75 3.30 4.40
1hf9A00 83.86 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 7 63 0.97 1.54
1jocA01 83.44 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 16 61 1.03 1.67
1gmjD00 82.82 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 1 66 2.58 3.90
2p7jB01 82.60 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 12 60 1.18 1.97
1pfiA00 82.55 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 10 70 2.15 3.04
3kpeA00 82.12 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 8 69 2.76 3.99
1jekA00 81.60 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 12 61 1.69 2.75
1ybkA00 81.47 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 7 76 3.59 4.67
2ifoA00 81.41 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 8 70 2.51 3.55
3cx5E01 81.25 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 3 63 2.62 4.15
3effK02 81.21 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 11 69 2.61 3.77
1wt6B00 80.97 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 3 56 1.56 2.75
1piqA00 80.83 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 9 47 0.52 1.09
1j1dB00 80.81 Response to calcium ionTroponin C bindingPositive regulation of ATPase activityActin bindingNegative regulation of ATPase activity 1.20.5.350 70 4 67 2.83 4.21
1ifpA00 80.42 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 6 67 3.11 4.59
1favA00 80.42 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 4 62 2.65 4.22
1tiiC00 80.12 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 11 55 2.02 3.65
1junA00 80.09 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 20 63 1.77 2.81
2w83C00 79.88 Homo sapiensIntegral to membraneC-Jun-amino-terminal kinase-interacting protein 4SpermatogenesisPositive regulation of cell migration 1.20.5.1000 67 4 55 2.74 4.96
1qbzA00 79.72 Simian immunodeficiency virusEnvelope glycoprotein 1.10.287.210 102 3 49 1.07 2.18
1svfC00 79.53 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 0 56 2.74 4.81
2dw3A01 79.11 Intrinsic membrane protein pufXRhodobacter sphaeroides 2.4.1 1.20.5.920 55 7 72 3.39 4.69
2o1kA00 79.04 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 7 56 2.75 4.83
1u57A00 78.56 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 6 69 3.25 4.69
2basA02 78.46 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 6 56 2.73 4.80
3efgA00 78.08 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 6 52 2.58 4.93
1dh3A00 78.06 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 7 61 2.63 4.27
2qjyC01 77.51 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 6 50 1.45 2.86
2hr3A01 77.48 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 0 46 1.18 2.56
2r9iA00 77.47 Putative phage capsid proteinCorynebacterium diphtheriae 1.10.287.80 69 4 52 2.12 4.06
2zjsE00 77.22 Protein exportBacterial secretion systemThermus thermophilus HB8Preprotein translocase subunit secEPreprotein translocase subunit SecE 1.20.5.1030 46 4 63 2.73 4.33
1vf5C03 76.03 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 9 46 1.42 3.08
1jmmA01 75.42 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 6 49 1.81 3.68
1jm0A00 74.07 1.20.5.420 48 2 40 1.46 3.65
1s3jB01 73.49 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 6 46 1.96 4.25
1fdoA05 73.35 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 14 41 1.52 3.66
2r44A01 72.54 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 11 40 1.09 2.73
2oarE02 71.29 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 13 33 1.27 3.75
1mqsB00 70.83 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 15 40 1.75 4.38
1be3K00 69.79 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 4 33 0.96 2.84
3l4jA05 69.68 Reciprocal meiotic recombinationDNA topoisomerase 2Regulation of mitotic recombinationDNA topoisomerase II [EC:5.99.1.3]DNA strand elongation involved in DNA replication 1.10.268.10 153 10 30 1.19 3.87
3c8vA04 67.53 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 5 29 0.79 2.70
2oarA02 66.56 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 5 26 0.42 1.61
2qiwA02 64.54 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 11 27 0.98 3.54
1f8vD00 62.91 Pariacato virusProtein alpha 1.20.5.280 25 4 27 1.31 4.73
1d66B02 61.13 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 0 23 0.46 1.99
1mkmA02 58.39 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 0 21 0.62 2.88
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Displaying entries 1 to 64 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2e42A00
DKHSDEYKIRRERNNIAARKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFK
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2e42A00
VKSKAKKTVDKHSDEYKIRRERNNIAARKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPE
BLAST against CATH

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Domain History Events (8)

Domain assigned by auto on 22 Dec 2007 14:13

Assigning to "1.20.5.170" based on similarity with "2e42B00"

Flow stage update by auto on 22 Dec 2007 14:13

No in_process hits for Domain "2e42A00" ready to be processed

Update comment by auto on 22 Dec 2007 11:34

Domain "2e42A00" hits Domain "2e42B00" (100% over 100%) which is currently in process

Flow stage update by auto on 22 Dec 2007 11:11

Domain "2e42A00" hits Domain "2e42B00" (100% over 100%) which is currently in process

Flow stage update by auto on 22 Dec 2007 11:11

NW result present for Domain "2e42A00"

Flow stage update by auto on 22 Dec 2007 08:05

All required files are present for Domain "2e42A00"

Flow stage update by auto on 21 Dec 2007 08:33

Beginning processing for Domain "2e42A00"

Insertion by auto on 21 Dec 2007 08:05

Final ChopClose added based on similarity with "1gtwA"