CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.20
Functional Family D-alanine--D-alanine ligase

Enzyme Information

6.3.2.4
D-alanine--D-alanine ligase.
based on mapping to UniProt P07862
ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
-!- Involved with EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in the synthesis of a cell-wall peptide.

UniProtKB Entries (1)

P07862
DDLB_ECOLI
Escherichia coli K-12
D-alanine--D-alanine ligase B

PDB Structure

PDB 2DLN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Vancomycin resistance: structure of D-alanine:D-alanine ligase at 2.3 A resolution.
Fan, C., Moews, P.C., Walsh, C.T., Knox, J.R.
Science