CATH Domain: 2cxnA02

2cxnA02

PDB 2cxn, Chain A, Domain 2

CATH Code	Level Description	Links
3	Alpha Beta
3.40	3-Layer(aba) Sandwich
3.40.50	Rossmann fold
3.40.50.10490	Glucose-6-phosphate isomerase like protein; domain 1	Gene3D
3.40.50.10490.2
3.40.50.10490.2.1
3.40.50.10490.2.1.1
3.40.50.10490.2.1.1.1
3.40.50.10490.2.1.1.1.1

Structure
Sequence
History

[top]
Segment boundaries for domain 2cxnA02

Domain	Start PDB Residue	Stop PDB Residue
2cxnA01	1	99
2cxnA01	295	515
2cxnA02	100	294
2cxnA03	516	556

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (5 entries)

There are 5 matching structural neighberhood comparisons for CATH ID 3.40.50.10490.2.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
2o2cA02	88.54	Glucose-6-phosphate isomerase, glycosomalTrypanosoma brucei brucei	3.40.50.10490	134	61	66	1.01	1.53
2q8nA02	85.66	Thermotoga maritimaAmino sugar and nucleotide sugar metabolismGlucose-6-phosphate isomeraseGlucose-6-phosphate isomerase [EC:5.3.1.9]Metabolic pathways	3.40.50.10490	162	26	75	2.27	2.99
3ff1B02	85.24	Amino sugar and nucleotide sugar metabolismMetabolic pathwaysStarch and sucrose metabolismPentose phosphate pathwayGlycolysis / Gluconeogenesis	3.40.50.10490	179	22	86	2.63	3.05
3i0zA01	75.98	Sugar isomerase domain protein AgaSTagatose-6-phosphate ketose/aldose isomerase [EC:5.-.-.-]Streptococcus pneumoniae	3.40.50.10490	201	9	79	3.75	4.74
2o2cC01	64.51	Glucose-6-phosphate isomerase, glycosomalTrypanosoma brucei brucei	3.40.50.10490	379	23	17	0.47	2.70

[top]
Domain ATOM Sequence

>pdb|2cxnA02
HVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGP
RVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGID
PQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFE

BLAST against CATH

[top]
Domain COMBS Sequence

>pdb|2cxnA02
HVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGP
RVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGID
PQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFE

BLAST against CATH

[top]
Domain History Events (16)

Domain assigned by auto on 02 Nov 2006 14:30

Assigning to "3.40.50.10490" based on similarity with "2cxrA02"

Flow stage update by auto on 02 Nov 2006 14:25

No in_process hits for Domain "2cxnA02" ready to be processed

Update comment by auto on 02 Nov 2006 10:06

Domain "2cxnA02" hits Domain "2cxrB02" (100% over 100%) which is currently in process

Update comment by auto on 02 Nov 2006 06:12

Domain "2cxnA02" hits Domain "2cxrA02" (100% over 100%) which is currently in process

Update comment by auto on 02 Nov 2006 03:17

Domain "2cxnA02" hits Domain "2cxuA02" (100% over 100%) which is currently in process

Update comment by auto on 01 Nov 2006 21:56

Domain "2cxnA02" hits Domain "2cxuB02" (100% over 100%) which is currently in process