CATH Domain: 2cxnA01

2cxnA01

PDB 2cxn, Chain A, Domain 1

CATH Code	Level Description	Links
3	Alpha Beta
3.40	3-Layer(aba) Sandwich
3.40.50	Rossmann fold
3.40.50.10490	Glucose-6-phosphate isomerase like protein; domain 1	Gene3D
3.40.50.10490.20
3.40.50.10490.20.1
3.40.50.10490.20.1.1
3.40.50.10490.20.1.1.1
3.40.50.10490.20.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 2cxnA01

Domain	Start PDB Residue	Stop PDB Residue
2cxnA01	1	99
2cxnA01	295	515
2cxnA02	100	294
2cxnA03	516	556

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (1 entries)

There are 1 matching structural neighberhood comparisons for CATH ID 3.40.50.10490.20.1.1.1.1 (SIMAX score < 5)

Match Depth	Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
	2o2cC01	90.85	Glucose-6-phosphate isomerase, glycosomalTrypanosoma brucei brucei	3.40.50.10490	379	49	81	0.86	1.06

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Domain ATOM Sequence

>pdb|2cxnA01
MAALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNTNHGHILVDYSKNLVSKEVMQMLVELAKSRGVEAA
RDNMFSGSKINYTEDRAVLQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG
DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEA
LMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGV

BLAST against CATH

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Domain COMBS Sequence

>pdb|2cxnA01
MAALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNTNHGHILVDYSKNLVSKEVMQMLVELAKSRGVEAA
RDNMFSGSKINYTEDRAVLQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG
DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEA
LMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGV

BLAST against CATH

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Domain History Events (17)

Domain assigned by auto on 02 Nov 2006 18:17

Assigning to "3.40.50.10490" based on similarity with "2cxrA01"

Flow stage update by auto on 02 Nov 2006 18:14

No in_process hits for Domain "2cxnA01" ready to be processed

Update comment by auto on 02 Nov 2006 14:25

Domain "2cxnA01" hits Domain "2cxrB01" (100% over 100%) which is currently in process

Update comment by auto on 02 Nov 2006 10:06

Domain "2cxnA01" hits Domain "2cxrA01" (100% over 100%) which is currently in process

Update comment by auto on 02 Nov 2006 06:12

Domain "2cxnA01" hits Domain "2cxoB01" (100% over 100%) which is currently in process

Update comment by auto on 02 Nov 2006 03:17

Domain "2cxnA01" hits Domain "2cxuA01" (100% over 100%) which is currently in process

Update comment by auto on 01 Nov 2006 21:56

Domain "2cxnA01" hits Domain "2cxuB01" (100% over 100%) which is currently in process