CATH Domain: 2ck3A01

2ck3A01

PDB 2ck3, Chain A, Domain 1

CATH Code	Level Description	Links
2	Mainly Beta
2.40	Beta Barrel
2.40.30	Elongation Factor Tu (Ef-tu); domain 3
2.40.30.20		Gene3D
2.40.30.20.1
2.40.30.20.1.1
2.40.30.20.1.1.1
2.40.30.20.1.1.1.1
2.40.30.20.1.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 2ck3A01

Domain	Start PDB Residue	Stop PDB Residue
2ck3A01	24	93
2ck3A02	94	379
2ck3A03	380	510

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (19 entries)

There are 19 matching structural neighberhood comparisons for CATH ID 2.40.30.20.1.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
2wssA01	91.90	F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]Huntington's diseaseParkinson's diseaseOxidative phosphorylationBos taurus	2.40.30.20	93	100	75	0.49	0.65
2ck3D01	90.08	ATP catabolic processParkinson's diseaseOxidative phosphorylationAlzheimer's diseaseMetabolic pathways	2.40.10.170	73	15	91	1.59	1.73
2fvgA02	85.09	Endoglucanase [EC:3.2.1.4]Thermotoga maritimaStarch and sucrose metabolismEndoglucanase	2.40.30.40	76	20	84	2.56	3.04
1y0yA02	83.84	Endoglucanase [EC:3.2.1.4]Starch and sucrose metabolismPyrococcus horikoshiiTetrahedral aminopeptidase	2.40.30.40	81	12	80	2.44	3.04
2ey4C00	83.74	Pyrococcus furiosusSmall nucleolar rnp gar1-like proteinRNA-binding protein	2.40.10.230	73	14	91	3.00	3.27
1yloA02	83.56	Shigella flexneriPutative uncharacterized protein	2.40.30.40	76	18	81	2.47	3.03
2greF02	83.41	Aminopeptidase [EC:3.4.11.-]Deblocking aminopeptidaseBacillus cereus ATCC 14579	2.40.30.40	75	17	80	2.55	3.19
3kl9A02	83.35	Glutamyl aminopeptidase [EC:3.4.11.7]Glutamyl aminopeptidaseStreptococcus pneumoniae R6	2.40.30.40	74	14	79	2.39	3.00
3isxA02	82.14	Endoglucanase [EC:3.2.1.4]Thermotoga maritimaStarch and sucrose metabolismEndoglucanase	2.40.30.40	84	11	76	2.47	3.24
1vhoA02	81.66	Endoglucanase [EC:3.2.1.4]Thermotoga maritimaStarch and sucrose metabolismEndoglucanase	2.40.30.40	76	14	78	3.68	4.66
3cpxA02	81.41	Aminopeptidase, M42 familyCytophaga hutchinsonii ATCC 33406	2.40.30.40	61	13	80	2.83	3.54
1pkyC03	80.60	Purine metabolismPyruvate metabolismMetabolic pathwaysGlycolysis / GluconeogenesisMembrane	2.40.33.10	68	11	75	2.31	3.05
1i8dA01	79.86	Riboflavin metabolismMetabolic pathwaysRiboflavin synthase activityRiboflavin synthase alpha chain [EC:2.5.1.9]Riboflavin synthase alpha chain	2.40.30.20	89	17	77	3.36	4.33
1vhkA01	79.37	Bacillus subtilisRibosomal RNA small subunit methyltransferase ERibosomal RNA small subunit methyltransferase E [EC:2.1.1.-]	2.40.240.20	71	5	78	3.78	4.79
1wb1A04	78.37	Methanococcus maripaludisMJ0495-like protein	2.40.10.190	79	11	83	3.99	4.78
1v5vA03	75.85	Pyrococcus horikoshiiProbable aminomethyltransferase	2.40.30.110	75	10	56	2.77	4.95
1i8dC02	75.46	Riboflavin metabolismMetabolic pathwaysRiboflavin synthase activityRiboflavin synthase alpha chain [EC:2.5.1.9]Riboflavin synthase alpha chain	2.40.30.20	88	5	70	3.10	4.40
3bmvA03	75.11	Cyclomaltodextrin glucanotransferaseThermoanaerobacterium thermosulfurigenes	2.60.40.10	80	12	78	3.72	4.72
2d9rA00	72.01	Porphyromonas gingivalisPutative uncharacterized protein	2.40.30.100	82	4	82	4.06	4.90

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Domain ATOM Sequence

>pdb|2ck3A01
DLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGA

BLAST against CATH

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Domain COMBS Sequence

>pdb|2ck3A01
DLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGA

BLAST against CATH

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Domain History Events (11)

Domain assigned by auto on 01 Nov 2006 18:34

Assigning to "2.40.30.20" based on similarity with "2f43A01"