CATH Domain: 2c78A01

There are 31 matching structural neighberhood comparisons for CATH ID 3.40.50.300.6.1.1.1.1 (SIMAX score < 5)

Match Depth	Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
	1zunB01	85.10	Selenoamino acid metabolismSulfur metabolismPurine metabolismSulfate adenylate transferase, subunit 1/adenylylsulfate kinaseMetabolic pathways	3.40.50.300	191	26	83	3.78	4.51
	1kk1A01	84.82	Pyrococcus abyssiTranslation initiation factor eIF-2 gamma subunitTranslation initiation factor 2 subunit gamma	3.40.50.300	196	29	80	3.79	4.74
	1z0jA00	83.36	Ras-related protein Rab-22AMus musculusGTPase activityGTP bindingProtein binding	3.40.50.300	169	15	77	2.88	3.74
	3ievA01	83.21	GTP-binding protein era homologGTP-binding protein EraAquifex aeolicus	3.40.50.300	175	17	75	2.75	3.64
	1wb1C01	83.19	Methanococcus maripaludisMJ0495-like protein	3.40.50.300	185	24	82	4.03	4.89
	1r2qA00	83.13	Ras-related protein Rab-5AGTP bindingEndocytosisGDP bindingGTPase activity	3.40.50.300	170	13	77	2.92	3.76
	1jnyA01	83.06	Sulfolobus solfataricusElongation factor 1-alphaElongation factor EF-1 alpha subunit [EC:3.6.5.3]	3.40.50.300	211	30	78	3.24	4.12
	3cx8A01	82.86	Rho protein signal transductionIn utero embryonic developmentGTPase activityPlatelet activationRegulation of cell migration	3.40.50.300	193	11	77	2.49	3.23
	1m7bA00	82.79	Actin cytoskeleton organizationRho-related GTP-binding protein RhoEGTPase activityGTP bindingCell adhesion	3.40.50.300	179	10	77	2.66	3.45
	2x19A00	82.70	Exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Nucleus organizationNucleusNucleocytoplasmic transportProtein binding	3.40.50.300	172	12	77	3.51	4.55
	2erxA00	82.64	DIRAS family, GTP-binding Ras-like 2Homo sapiensGTP-binding protein Di-Ras2	3.40.50.300	168	13	77	3.26	4.23
	1n0uA01	82.57	Positive regulation of translational elongationElongation factor 2Elongation factor EF-2 [EC:3.6.5.3]Protein bindingRibonucleoprotein binding	3.40.50.300	210	21	77	3.11	4.01
	1mh1A00	82.47	MAPK signaling pathwayNatural killer cell mediated cytotoxicityVEGF signaling pathwayFocal adhesionToll-like receptor signaling pathway	3.40.50.300	183	15	77	3.04	3.92
	1x3sA00	82.28	Ras-related protein Rab-18IntracellularHomo sapiens	3.40.50.300	175	13	77	3.20	4.15
	1g7sA01	82.21	Methanothermobacter thermautotrophicus str. Delta HTranslation initiation factor IF-2 unclassified subunitProbable translation initiation factor IF-2	3.40.50.300	221	22	72	3.01	4.13
	1cipA01	82.03	Rattus norvegicusGuanine nucleotide-binding protein G(i) subunit alpha-1Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptideChagas diseaseChemokine signaling pathway	3.40.50.300	197	13	79	2.73	3.43
	2h57B00	81.67	ADP-ribosylation factor-like 6ADP-ribosylation factor-like protein 6Homo sapiens	3.40.50.300	164	18	78	3.01	3.86
	1xtqA00	81.50	Insulin signaling pathwayMTOR signaling pathwayGTP-binding protein RhebGTPase activityGTP binding	3.40.50.300	169	14	77	3.32	4.31
	1mkyA02	81.49	Thermotoga maritimaGTP-binding proteinGTP-binding protein engA	3.40.50.300	149	22	71	3.10	4.32
	1wmsA00	80.97	Ras-related protein Rab-9ALysosomeGTP bindingProtein bindingGDP binding	3.40.50.300	170	14	76	2.96	3.89
	1ukvY00	80.78	GTP-binding protein YPT1Endoplasmic reticulum membraneRab family, otherER to Golgi vesicle-mediated transportProtein binding	3.40.50.300	197	10	76	3.38	4.41
	1sulB00	80.76	Bacillus subtilisProbable GTP-binding protein engBGTP-binding protein	3.40.50.300	195	12	76	3.43	4.48
	1bofA01	80.55	Rattus norvegicusGuanine nucleotide-binding protein G(i) subunit alpha-1Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptideChagas diseaseChemokine signaling pathway	3.40.50.300	203	12	73	2.63	3.57
	2ce2X00	80.47	Neurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathwayTight junction	3.40.50.300	166	13	77	3.25	4.22
	1mkyA01	80.06	Thermotoga maritimaGTP-binding proteinGTP-binding protein engA	3.40.50.300	153	19	68	3.24	4.71
	3c5cB00	79.86	Ras-like protein family member 12Homo sapiensRas-like, family 12	3.40.50.300	164	13	75	3.38	4.47
	1z2aA00	79.58	Mus musculusRegulation of smoothened signaling pathwaySpinal cord dorsal/ventral patterningRas-related protein Rab-23Negative regulation of proteolysis	3.40.50.300	164	13	77	3.37	4.37
	2qu8A00	79.06		3.40.50.300	194	10	75	3.71	4.91
	1darA01	78.94	Thermus thermophilus HB8Elongation factor GElongation factor EF-G [EC:3.6.5.3]	3.40.50.300	258	23	59	2.83	4.74
	1mr3F00	78.65	Golgi-associated vesicleIdentical protein bindingGTPase activityIntra-Golgi vesicle-mediated transportER to Golgi vesicle-mediated transport	3.40.50.300	177	14	78	3.48	4.46
	1f6bB00	78.28	Cricetulus griseusGTP-binding protein SAR1b	3.40.50.300	180	12	72	3.17	4.36

>pdb|2c78A01
KPHVNVGTIGHVDHGKTTLTAALTYVAAAENPNVEVKDYGDIDKAPEERARGITINTAHVEYETAKRHYSHVDCPGHADY
IKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVFMNKVDMVDDPELLDLVEMEVRDLLNQYEFPGDEV
PVIRGSALLALEQMHRNPKTRRGENEWVDKIWELLDAIDEYIPTP    

>pdb|2c78A01
AKGEFVRTKPHVNVGTIGHVDHGKTTLTAALTYVAAAENPNVEVKDYGDIDKAPEERARGITINTAHVEYETAKRHYSHV
DCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVFMNKVDMVDDPELLDLVEMEVRDLLNQ
YEFPGDEVPVIRGSALLALEQMHRNPKTRRGENEWVDKIWELLDAIDEYIPTP