CATH Domain: 2bvrH02 XML data for domain: 2bvrH02

Molscript image for 2bvrH02
2bvrH02
PDB coordinates for domain 2bvrH02

PDB 2bvr, Chain H, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.10
2.40.10.10.10.1
2.40.10.10.10.1.1
2.40.10.10.10.1.1.1
2.40.10.10.10.1.1.1.1

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Segment boundaries for domain 2bvrH02

Chopping figure for domain 2bvrH02
DomainStart PDB ResidueStop PDB Residue
2bvrH01 16 27
2bvrH01 121 232
2bvrH02 28 120
2bvrH02 233 243

Structural Neighbourhood (34 entries)

There are 34 matching structural neighberhood comparisons for CATH ID 2.40.10.10.10.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 34 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ym0A02 91.99 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 27 93 1.08 1.16
1eaxA02 91.85 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 115 31 98 1.93 1.96
2jkhA02 91.16 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 34 90 1.48 1.64
1bioA02 91.08 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 26 91 1.71 1.87
1nn6A02 90.91 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 30 88 1.46 1.64
3govB02 90.88 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 30 91 1.74 1.91
3gylB02 90.80 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 111 36 91 1.44 1.58
2anyA02 90.77 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 34 93 2.06 2.21
1a7sA02 90.67 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 21 87 1.11 1.26
1gj7B02 90.66 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 25 93 1.30 1.39
1fiwA02 90.63 Ovis ariesAcrosinDrug binding 2.40.10.10 120 31 91 1.48 1.61
1gvzA02 90.59 Equus caballusKallikrein-1E2 2.40.10.10 115 26 88 1.36 1.53
1p57B02 90.30 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 31 88 1.56 1.75
2r0lA02 90.28 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 25 92 1.47 1.59
1orfA02 90.23 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 30 88 1.63 1.84
2wphS02 89.80 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 29 90 1.68 1.86
2asuB02 89.12 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 24 87 1.90 2.16
2hlcA01 88.92 CollagenaseHypoderma lineatum 2.40.10.10 104 30 84 2.55 3.02
1elvA01 88.83 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 34 79 1.63 2.06
2qxiA02 88.78 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 34 81 1.18 1.44
2aiqA02 88.32 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 25 87 2.16 2.46
1q3xA03 88.30 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 31 86 1.94 2.25
3beuA02 87.11 Streptomyces griseusTrypsin 2.40.10.10 99 23 83 2.42 2.89
1rrkA02 86.56 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 25 78 2.92 3.71
1p3cA02 84.83 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 14 88 2.60 2.93
1agjA02 83.95 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 20 85 2.89 3.39
2o8lA02 82.06 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 10 76 3.05 3.98
2pkaA00 81.53 Sus scrofaGlandular kallikrein 2.40.10.10 80 27 58 1.49 2.54
2hntC00 80.04 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 67 82 47 0.58 1.22
1lcyA01 79.80 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 12 70 2.58 3.65
1sotA01 78.37 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 10 72 3.25 4.51
2halA01 76.93 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 12 78 3.42 4.36
1arbA02 75.91 Achromobacter lyticusProtease 1 2.40.10.10 137 13 69 3.25 4.69
1eptA00 67.63 Sus scrofaTrypsin 2.40.10.10 43 34 26 1.17 4.38
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Displaying entries 1 to 34 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|2bvrH02
PWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNW
RENLDRDIALMKLKKPVAFSDYIHPRLKKWIQKVID
BLAST against CATH

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Domain COMBS Sequence 

>pdb|2bvrH02
PWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNW
RENLDRDIALMKLKKPVAFSDYIHPRLKKWIQKVID
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 08 Aug 2007 14:29

Assigning to "2.40.10.10" based on similarity with "1ai8H02"

Flow stage update by auto on 08 Aug 2007 14:25

No in_process hits for Domain "2bvrH02" ready to be processed

Flow stage update by auto on 08 Aug 2007 14:25

NW result present for Domain "2bvrH02"

Flow stage update by auto on 21 Jul 2007 23:04

All required files are present for Domain "2bvrH02"

Flow stage update by auto on 20 Jul 2007 19:34

Beginning processing for Domain "2bvrH02"

Insertion by auto on 20 Jul 2007 18:06

Final ChopClose added based on similarity with "1hxeH"