CATH Domain: 2aprA02 XML data for domain: 2aprA02

Molscript image for 2aprA02
2aprA02
PDB coordinates for domain 2aprA02

PDB 2apr, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.70 Cathepsin D, subunit A; domain 1
2.40.70.10 Acid Proteases Gene3D
2.40.70.10.7
2.40.70.10.7.1
2.40.70.10.7.1.1
2.40.70.10.7.1.1.1
2.40.70.10.7.1.1.1.1

[top]
Segment boundaries for domain 2aprA02

Chopping figure for domain 2aprA02
DomainStart PDB ResidueStop PDB Residue
2aprA01 6 174
2aprA02 175 323

Structural Neighbourhood (9 entries)

There are 9 matching structural neighberhood comparisons for CATH ID 2.40.70.10.7.1.1.1.1 (SIMAX score < 5)

[1]
Displaying entries 1 to 9 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1j71A02 87.40 Candida tropicalisCandidapepsin 2.40.70.10 161 26 89 1.58 1.77
1dpjA02 86.78 Cellular response to starvationSporulation resulting in formation of a cellular sporeProteolysis involved in cellular protein catabolic processFungal-type vacuole lumenSaccharopepsin 2.40.70.10 154 28 95 2.35 2.46
1hrnA02 86.72 Renin-angiotensin systemAngiotensin maturationRegulation of MAPKKK cascadeExtracellular spaceRenin 2.40.70.10 158 19 93 2.14 2.30
1wkrA02 85.07 Irpex lacteusPolyporopepsin 2.40.70.10 170 24 84 2.50 2.97
2zjlA02 81.71 Beta-secretase 1Integral to plasma membraneBeta-aspartyl-peptidase activityProtein bindingBeta-amyloid metabolic process 2.40.70.10 197 14 67 2.30 3.43
1mppA02 81.26 Rhizomucor pusillusMucorpepsin 2.40.70.10 175 18 83 2.76 3.31
1lyaB00 80.47 LysosomeAspartic-type endopeptidase activityCathepsin D [EC:3.4.23.5]Homo sapiensCathepsin D 2.40.70.10 241 26 61 1.78 2.90
1t6eX02 79.91 Triticum aestivumXylanase inhibitor 2.40.70.10 187 13 79 2.79 3.50
1b5fB00 75.68 Preprocardosin ACynara cardunculus 2.40.70.10 87 24 52 1.81 3.46
[1]
Displaying entries 1 to 9 (page 1 of 1)


[top]
Domain ATOM Sequence 

>pdb|2aprA02
DSTKFKGSLTTVPIDNSRGWWGITVDRATVGTSTVASSFDGILDTGTTLLILPNNIAASVARAYGASDNGDGTYTISCDT
SAFKPLVFSINGASFQVSPDSLVFEEFQGQCIAGFGYGNWGFAIIGDTFLKNNYVVFNQGVPEVQIAPV
BLAST against CATH

[top]
Domain COMBS Sequence 

>pdb|2aprA02
DSTKFKGSLTTVPIDNSRGWWGITVDRATVGTSTVASSFDGILDTGTTLLILPNNIAASVARAYGASDNGDGTYTISCDT
SAFKPLVFSINGASFQVSPDSLVFEEFQGQCIAGFGYGNWGFAIIGDTFLKNNYVVFNQGVPEVQIAPV
BLAST against CATH

[top]
Domain History Events (4)

Update comment by auto on 16 Oct 2007 19:44

Around September/October 2007, this domain was renamed from "2apr002" to "2aprA02" as part of the work to deal with the remediation of the PDB (see http://remediation.wwpdb.org). Please see ticket:207 or wiki:Remediation on the CATH Trac system for more details.

Set cath from cathlist by auto on 05 Mar 2006 18:32

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:32

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 17:53

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"