CATH Domain: 1zoqA00

1zoqA00

PDB 1zoq, Chain A, Domain 0

CATH Code	Level Description	Links
2	Mainly Beta
2.60	Sandwich
2.60.200	Tumour Suppressor Smad4
2.60.200.10		Gene3D
2.60.200.10.4
2.60.200.10.4.1
2.60.200.10.4.1.1
2.60.200.10.4.1.1.1
2.60.200.10.4.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 1zoqA00

Domain	Start PDB Residue	Stop PDB Residue
1zoqA00	196	386

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (1 entries)

There are 1 matching structural neighberhood comparisons for CATH ID 2.60.200.10.4.1.1.1.1 (SIMAX score < 5)

Match Depth	Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
	1gxcA00	71.20	DNA damage response, signal transduction resulting in induction of apoptosisSenescenceSerine/threonine-protein kinase Chk2PML bodyProtein binding	2.60.200.20	116	7	57	2.77	4.81

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Domain ATOM Sequence

>pdb|1zoqA00
LVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALW
RAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQD
QPWTKRLVMVKVVPTCLRALVEMARVGGASS

BLAST against CATH

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Domain COMBS Sequence

>pdb|1zoqA00
LVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALW
RAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQD
QPWTKRLVMVKVVPTCLRALVEMARVGGASS

BLAST against CATH

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Domain History Events (11)

Domain assigned by auto on 01 Nov 2006 18:18

Assigning to "2.60.200.10" based on similarity with "1zoqB00"