CATH Domain: 1z57A01 XML data for domain: 1z57A01

Molscript image for 1z57A01
1z57A01
PDB coordinates for domain 1z57A01

PDB 1z57, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.200 Phosphorylase Kinase; domain 1
3.30.200.20 Phosphorylase Kinase; domain 1 Gene3D
3.30.200.20.9
3.30.200.20.9.1
3.30.200.20.9.1.1
3.30.200.20.9.1.1.1
3.30.200.20.9.1.1.1.1

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Segment boundaries for domain 1z57A01

Chopping figure for domain 1z57A01
DomainStart PDB ResidueStop PDB Residue
1z57A01 -2 220
1z57A01 225 243
1z57A02 221 224
1z57A02 244 482

Structural Neighbourhood (49 entries)

There are 49 matching structural neighberhood comparisons for CATH ID 3.30.200.20.9.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 49 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1wakA01 92.00 Regulation of mRNA processingRNA splicingSerine/threonine-protein kinase SRPK1NucleusProtein binding 3.30.200.20 92 33 93 1.37 1.46
1xbbA01 87.39 T cell receptor complexTyrosine-protein kinase SYKOrgan morphogenesisLeukocyte cell-cell adhesionCell proliferation 3.30.200.20 83 25 86 4.03 4.68
2wtkC01 86.50 NucleusSerine/threonine-protein kinase 11Cell cycle arrestProtein bindingSerine/threonine-protein kinase 11 [EC:2.7.11.9] 3.30.200.20 89 28 81 1.96 2.39
3f61A01 86.44 Serine/threonine-protein kinase pknBSerine/threonine protein kinase, bacterial [EC:2.7.11.1]Mycobacterium tuberculosis 3.30.200.20 91 23 89 2.63 2.94
2zv2A01 86.41 Calcium ion bindingRegulation of protein kinase activityPositive regulation of transcriptionMAPKKK cascadeCytoplasm 3.30.200.20 77 28 79 2.03 2.54
3d5vA01 86.35 Danio rerioPolo-like kinase 3.30.200.20 92 28 90 2.21 2.44
1x8bA01 86.22 Homo sapiensWee1-like protein kinaseProtein binding 3.30.200.20 84 19 85 2.98 3.50
2wtjA01 86.09 DNA damage response, signal transduction resulting in induction of apoptosisSenescenceSerine/threonine-protein kinase Chk2PML bodyProtein binding 3.30.200.20 79 26 84 3.22 3.83
3hmmA01 86.02 Type II transforming growth factor beta receptor bindingPeptidyl-threonine phosphorylationPositive regulation of cellular component movementPathway-restricted SMAD protein phosphorylationResponse to cholesterol 3.30.200.20 84 16 82 2.38 2.87
2i6lA01 85.82 Protein phosphorylationMitogen-activated protein kinase 6Homo sapiensSignal transductionMitogen-activated protein kinase 4/6 [EC:2.7.11.24] 3.30.200.20 91 24 82 1.98 2.39
2acxA02 85.71 G protein-coupled receptor kinase 6Homo sapiensRegulation of G-protein coupled receptor protein signaling pathway 3.30.200.20 91 24 88 3.84 4.35
2h6dA01 85.67 Insulin signaling pathwayHypertrophic cardiomyopathy (HCM)Adipocytokine signaling pathwayRegulation of autophagyMTOR signaling pathway 3.30.200.20 86 26 87 2.59 2.97
1q5kA01 85.66 Hedgehog signaling pathwayNeurotrophin signaling pathwayAlzheimer's diseaseT cell receptor signaling pathwayER overload response 3.30.200.20 95 19 80 2.57 3.21
1tkiA01 85.65 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 3.30.200.20 84 26 87 2.50 2.87
3fhrA01 85.57 Response to stressMAP kinase kinase activityNucleusMitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]MAPK signaling pathway 3.30.200.20 80 25 80 2.11 2.61
1xwsA01 85.44 Transcription factor bindingPositive regulation of cyclin-dependent protein kinase activity involved in G1/SManganese ion bindingNegative regulation of apoptosisProtein binding 3.30.200.20 92 21 86 2.58 2.99
3k3iA01 85.43 Cellular component movementMAP kinase kinase activityProtein bindingChemotaxisMitogen-activated protein kinase 14 3.30.200.20 92 23 86 2.42 2.81
3c0iA01 85.36 Actin cytoskeletonGuanylate kinase activityPeripheral plasma membrane protein CASKCell adhesionHomo sapiens 3.30.200.20 88 28 87 2.63 3.01
3f3zA01 85.35 Cryptosporidium parvum Iowa IICalcium-dependent protein kinase [EC:2.7.11.1]Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands 3.30.200.20 81 24 85 2.54 2.98
2ac3A01 85.24 MAP kinase-interacting serine/threonine-protein kinase 2ATP bindingProtein phosphorylationHomo sapiensProtein serine/threonine kinase activity 3.30.200.20 80 28 82 2.24 2.70
2a19C01 85.11 Eukaryotic translation initiation factor 2alpha kinase activityProtein phosphatase type 2A regulator activityInterferon-induced, double-stranded RNA-activated protein kinaseProtein bindingNegative regulation of osteoblast proliferation 3.30.200.20 95 19 87 2.75 3.15
2clqA01 85.00 Induction of apoptosis by extracellular signalsProtein homodimerization activityMitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]Neurotrophin signaling pathwayATP binding 3.30.200.20 85 27 81 2.31 2.82
1zy4A01 84.98 Eukaryotic translation initiation factor 2alpha kinase activityProtein bindingSerine/threonine-protein kinase GCN2DNA damage checkpointRegulation of translational initiation 3.30.200.20 94 21 88 3.07 3.48
2jamA01 84.51 Calcium/calmodulin-dependent protein kinase type 1GHomo sapiensCalcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] 3.30.200.20 75 26 79 2.42 3.03
2rkuA01 84.38 Polo-like kinase 1 [EC:2.7.11.21]Polo kinase kinase activityProgesterone-mediated oocyte maturationCell proliferationOocyte meiosis 3.30.200.20 89 25 86 3.03 3.52
2vgpB01 84.20 Serine/threonine-protein kinase 12-AHistone H3-S10 phosphorylationChromosome, centromeric regionProtein bindingChromatin 3.30.200.20 89 22 86 2.96 3.44
2weiA01 84.09 Cryptosporidium parvum Iowa IICalmodulin-domain protein kinase 1, putative 3.30.200.20 90 26 89 4.05 4.53
2b9hA01 83.70 MAPK signaling pathway - yeastMating projection tipMitogen-activated protein kinase FUS3Invasive growth in response to glucose limitationNegative regulation of MAPKKK cascade 3.30.200.20 110 21 79 3.26 4.12
2qkwB01 83.41 Solanum pimpinellifoliumProtein kinaseProtein binding 3.30.200.20 72 22 73 2.16 2.94
2b1pA01 83.41 MAP kinase kinase activityMitogen-activated protein kinase 10Homo sapiensProtein binding 3.30.200.20 101 20 86 3.47 4.03
3fpqA01 83.32 Rattus norvegicusSerine/threonine-protein kinase WNK1Protein bindingPotassium channel inhibitor activityATP binding 3.30.200.20 91 18 89 3.18 3.56
1omwA03 83.25 MembraneG-protein coupled receptor kinase activityNegative regulation of the force of heart contraction by chemical signalChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 3.30.200.20 107 19 77 2.51 3.24
2r3iA01 83.12 Progesterone-mediated oocyte maturationPathways in cancerSmall cell lung cancerOocyte meiosisProstate cancer 3.30.200.20 76 30 78 2.87 3.65
2jiiA01 83.05 Serine/threonine-protein kinase VRK3Homo sapiensProtein binding 3.30.200.20 110 9 78 2.76 3.53
1ckiA01 82.30 SpindleRattus norvegicusHedgehog signaling pathwaySoluble fractionCircadian rhythm - mammal 3.30.200.20 64 15 67 2.25 3.36
1nd4A01 82.01 Aminoglycoside 3'-phosphotransferaseKlebsiella pneumoniae 3.30.200.20 86 15 84 3.38 4.02
1ob3A01 81.88 Cyclin-dependent kinase [EC:2.7.11.22]Cell division control protein 2 homologPlasmodium falciparum K1 3.30.200.20 83 21 82 3.61 4.35
1o6lA02 81.74 Jak-STAT signaling pathwayRAC-beta serine/threonine-protein kinaseNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.30.200.20 117 23 70 3.12 4.45
2w5aA01 81.61 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1]Regulation of mitosisSerine/threonine-protein kinase Nek2CentrosomeCentrosome separation 3.30.200.20 64 17 64 2.56 3.94
1kutB01 81.51 Thermotoga maritimaPhosphoribosylaminoimidazole-succinocarboxamide synthasePurine metabolismPhosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]Metabolic pathways 3.30.200.20 88 9 64 2.14 3.30
2q83B01 81.34 Bacillus subtilisSpore coat protein ISpore coat protein I 3.30.200.20 97 12 82 3.52 4.27
2oo8X01 81.17 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 3.30.200.20 60 25 60 2.40 3.96
2bkkA01 81.02 Aminoglycoside 3'-phosphotransferaseAminoglycoside 3'-phosphotransferase [EC:2.7.1.95]Enterococcus faecalis 3.30.200.20 90 13 84 3.71 4.41
1tvoA01 80.83 Prion diseasesAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNon-small cell lung cancerAlzheimer's disease 3.30.200.20 121 22 71 2.94 4.09
2ppqA01 80.81 Glycine, serine and threonine metabolismMetabolic pathwaysAgrobacterium tumefaciens str. C58Homoserine kinaseHomoserine kinase type II [EC:2.7.1.39] 3.30.200.20 93 5 87 3.65 4.18
3kreA01 80.58 Phosphoribosylaminoimidazole-succinocarboxamide synthasePurine metabolismPhosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]Ehrlichia chaffeensis str. ArkansasMetabolic pathways 3.30.200.20 94 4 67 2.23 3.33
2jedB01 80.22 Protein kinase C theta typeProtein bindingT cell receptor signaling pathwayNovel protein kinase C [EC:2.7.11.13]Adipocytokine signaling pathway 3.30.200.20 125 23 65 2.59 3.95
3csvA01 79.61 Aminoglycoside phosphotransferaseRuegeria sp. TM1040 3.30.200.20 81 7 84 3.98 4.74
3dzoA02 78.16 Toxoplasma gondiiRop2 protein 3.30.200.20 118 11 78 3.56 4.52
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Displaying entries 1 to 49 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1z57A01
SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSVQMLE
WFEHHGHICIVFEL
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1z57A01
SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSVQMLE
WFEHHGHICIVFEL
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 12 Jul 2007 00:04

Assigning to "3.30.200.20" based on similarity with "1wbpA01"

Flow stage update by auto on 12 Jul 2007 00:02

No in_process hits for Domain "1z57A01" ready to be processed

Flow stage update by auto on 12 Jul 2007 00:02

NW result present for Domain "1z57A01"

Flow stage update by auto on 10 Jul 2007 02:18

All required files are present for Domain "1z57A01"

Flow stage update by auto on 09 Jul 2007 14:54

Beginning processing for Domain "1z57A01"

Insertion by cuff on 09 Jul 2007 13:59

nice chopping