CATH Domain: 1z2lA02

1z2lA02

PDB 1z2l, Chain A, Domain 2

CATH Code	Level Description	Links
3	Alpha Beta
3.30	2-Layer Sandwich
3.30.70	Alpha-Beta Plaits
3.30.70.360		Gene3D
3.30.70.360.6
3.30.70.360.6.1
3.30.70.360.6.1.1
3.30.70.360.6.1.1.1
3.30.70.360.6.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 1z2lA02

Domain	Start PDB Residue	Stop PDB Residue
1z2lA01	3	213
1z2lA01	329	413
1z2lA02	214	328

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (20 entries)

There are 20 matching structural neighberhood comparisons for CATH ID 3.30.70.360.6.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
1cg2A02	87.80	Pseudomonas sp. RS-16Carboxypeptidase G2	3.30.70.360	110	13	94	2.36	2.49
1xmbA02	85.92	Auxin metabolic processArabidopsis thalianaIAA-Ala conjugate hydrolase activityIAA-amino acid hydrolase ILR1-like 2	3.30.70.360	101	16	79	1.88	2.38
3ct9A02	83.16	Bacteroides thetaiotaomicronAcetylornithine deacetylase	3.30.70.360	104	18	86	2.76	3.21
1j27A00	81.43	Hypothetical proteinThermus thermophilusPutative uncharacterized protein	3.30.70.1120	98	7	80	2.89	3.61
1q8kA03	80.51	Translation initiation factor activityTranslation initiation factor eIF-2 alpha subunitEukaryotic translation initiation factor 2 subunit 1PolysomeHomo sapiens	3.30.70.1130	116	3	77	2.71	3.49
2ia0B02	78.95	Pyrococcus furiosusUncharacterized HTH-type transcriptional regulator PF0864	3.30.70.920	99	8	66	2.26	3.42
3bm7A00	78.33	Caulobacter vibrioidesPutative uncharacterized protein	3.30.70.900	101	9	76	3.47	4.53
2pd1A01	78.07	Nitrosomonas europaeaPutative uncharacterized protein	3.30.70.900	93	9	75	2.69	3.56
2nzcA00	77.91	Thermotoga maritimaPutative uncharacterized protein	3.30.70.1150	77	9	66	2.72	4.12
1x7vC00	77.47	Pseudomonas aeruginosaPutative uncharacterized protein	3.30.70.900	97	8	77	3.77	4.87
1in0A01	76.84	Hypothetical proteinHaemophilus influenzaeUPF0234 protein HI_1034	3.30.70.860	70	8	60	2.57	4.22
2pokA02	76.40	Lysine biosynthesisMetabolic pathwaysSuccinyl-diaminopimelate desuccinylase [EC:3.5.1.18]Peptidase, M20/M25/M40 familyStreptococcus pneumoniae	3.30.70.360	170	7	64	3.10	4.79
1u7lA01	76.28	V-type H+-transporting ATPase subunit C [EC:3.6.3.14]Oxidative phosphorylationVacuolar acidificationProtein bindingVacuolar proton-transporting V-type ATPase, V1 domain	3.30.70.1180	91	5	63	2.98	4.69
1vr6A01	76.19	Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysThermotoga maritima3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]Phospho-2-dehydro-3-deoxyheptonate aldolase	3.30.70.1140	75	9	63	3.07	4.84
2bbeA00	76.00	Shewanella oneidensisPutative uncharacterized protein	3.30.70.900	92	6	72	3.60	4.99
2iboA00	75.73	Streptococcus pneumoniaePutative uncharacterized protein	3.30.70.930	87	3	62	2.83	4.52
1lfwA03	75.73	Lactobacillus delbrueckii subsp. lactisBeta-Ala-Xaa dipeptidase	3.30.70.360	88	6	55	2.16	3.88
1s99A01	75.60	Bacillus subtilisPutative HMP/thiamine-binding protein ykoF	3.30.70.930	77	7	62	3.06	4.89
1qapA01	74.97	Nicotinate and nicotinamide metabolismMetabolic pathwaysNicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]Salmonella enterica subsp. enterica serovar TyphimuriumNicotinate-nucleotide pyrophosphorylase [carboxylating]	3.90.1170.20	122	6	63	3.04	4.75
2fgcA03	73.98	Butanoate metabolismC5-Branched dibasic acid metabolismPantothenate and CoA biosynthesisValine, leucine and isoleucine biosynthesisMetabolic pathways	3.30.70.1150	74	6	56	2.75	4.87

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Domain ATOM Sequence

>pdb|1z2lA02
GQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTD
AAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEE

BLAST against CATH

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Domain COMBS Sequence

>pdb|1z2lA02
GQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTD
AAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEE

BLAST against CATH

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Domain History Events (12)

Domain assigned by auto on 11 Feb 2008 14:13

Assigning to "3.30.70.360" based on similarity with "1z2lB02"