CATH Domain: 1yn8A00 XML data for domain: 1yn8A00

Molscript image for 1yn8A00
1yn8A00
PDB coordinates for domain 1yn8A00

PDB 1yn8, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.30 SH3 type barrels.
2.30.30.40 SH3 Domains Gene3D
2.30.30.40.21
2.30.30.40.21.1
2.30.30.40.21.1.1
2.30.30.40.21.1.1.1
2.30.30.40.21.1.1.1.1

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Segment boundaries for domain 1yn8A00

Chopping figure for domain 1yn8A00
DomainStart PDB ResidueStop PDB Residue
1yn8A00 1 59

Structural Neighbourhood (65 entries)

There are 65 matching structural neighberhood comparisons for CATH ID 2.30.30.40.21.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 65 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ov3A02 91.93 GTP bindingSoluble fractionSH3 domain bindingCellular defense responseSuperoxide anion generation 2.30.30.40 54 25 91 1.06 1.16
2j6fA00 91.23 CD2-associated proteinRufflePlasma membraneSH3 domain bindingStructural constituent of cytoskeleton 2.30.30.40 57 29 94 1.30 1.37
2vwfA00 91.18 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 56 26 94 1.32 1.39
2v1rA00 90.21 PeroxisomePeroxin-13Protein binding, bridgingPeroxisomal membrane protein PAS20Peroxisomal membrane 2.30.30.40 67 32 85 1.21 1.42
1ad5A01 90.20 Protein phosphorylationTyrosine-protein kinase HCKHomo sapiensMesoderm developmentProtein binding 2.30.30.40 63 25 92 1.71 1.86
2rqtA00 89.91 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing proteinArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1Fc gamma R-mediated phagocytosisHomo sapiensProtein binding 2.30.30.40 61 25 96 1.45 1.50
2ablA01 89.72 DNA damage response, signal transduction resulting in induction of apoptosisProto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2]Pathways in cancerNucleolusNeurotrophin signaling pathway 2.30.30.40 66 25 86 1.62 1.88
1ycsB02 89.65 Induction of apoptosisNF-kappaB bindingNegative regulation of cell cycleHomo sapiensApoptosis-stimulating of p53 protein 2 2.30.30.40 64 32 87 1.41 1.61
3ehrB01 89.43 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 62 33 90 1.67 1.85
1griA01 89.01 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 48 37 81 1.07 1.32
1jegA00 88.97 Tyrosine-protein kinase CSKProtein bindingCell-cell junctionMus musculusATP binding 2.30.30.40 60 23 96 1.55 1.60
2jteA00 88.75 Mus musculusCD2-associated protein 2.30.30.40 64 27 89 1.37 1.54
1x6bA01 88.75 Rho guanine nucleotide exchange factor 16Homo sapiens 2.30.30.40 64 25 90 1.74 1.92
2vknA00 88.51 MAPK signaling pathway - yeastIdentical protein bindingMating projection tipPseudohyphal growthOsmosensor activity 2.30.30.40 66 25 86 1.69 1.96
2csqA01 88.29 RIMS-binding protein 2Homo sapiens 2.30.30.40 65 32 86 1.45 1.68
1wx6A01 88.28 NCK adaptor proteinPositive regulation of T cell proliferationRegulation of epidermal growth factor receptor activityT cell receptor signaling pathwayEpidermal growth factor receptor signaling pathway 2.30.30.40 66 23 87 1.67 1.90
2js2A00 87.43 Receptor bindingNCK adaptor proteinPositive regulation of T cell proliferationT cell receptor signaling pathwayPositive regulation of actin filament polymerization 2.30.30.40 63 22 90 2.29 2.53
1uhfA00 87.17 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 69 22 81 1.21 1.49
1ng2A01 86.72 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 44 27 72 1.13 1.55
1awwA00 85.83 Phosphatidylinositol-3,4,5-trisphosphate bindingInduction of apoptosis by extracellular signalsIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.30.40 67 32 86 1.83 2.11
2epdA00 85.56 Rho protein signal transductionCytoskeleton organizationRho GTPase-activating protein 4Homo sapiensRho GTPase activator activity 2.30.30.40 76 20 75 1.56 2.08
1spkA00 85.17 Mus musculusBrain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2.30.30.40 72 22 81 1.82 2.22
1u3oA01 85.00 Rattus norvegicusVesicle-mediated transportProtein bindingAxonogenesisNeuron projection 2.30.30.40 62 23 88 2.16 2.43
1j3tA00 84.93 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 74 23 75 1.37 1.81
1bb9A00 84.85 Rattus norvegicusProtein heterodimerization activityProtein C-terminus bindingSynaptic vesicle endocytosisMyc box-dependent-interacting protein 1 2.30.30.40 83 30 71 1.62 2.28
2ke9A00 84.38 Caskin-2Homo sapiens 2.30.30.40 67 20 88 2.48 2.82
3i5rA00 84.34 ErbB-3 class receptor bindingInsulin-like growth factor receptor signaling pathwayInsulin receptor signaling pathwayGrowth hormone receptor signaling pathwayInsulin-like growth factor receptor binding 2.30.30.40 81 33 72 2.54 3.49
2heqA01 83.68 Bacillus subtilisSPBc2 prophage-derived uncharacterized protein yorP 2.30.30.40 54 7 88 2.60 2.95
1sf9A02 83.63 Bacillus subtilisUncharacterized protein yfhH 2.30.30.340 54 14 76 1.43 1.87
1mhnA00 83.12 Survival motor neuron proteinSurvival motor neuron proteinHomo sapiensProtein binding 2.30.30.140 59 6 84 2.75 3.25
2g3rA01 83.03 CytoplasmHomo sapiensTumor suppressor p53-binding protein 1Protein binding 2.30.30.140 53 15 81 2.37 2.91
2rh2A00 82.66 Dihydrofolate reductase type 2Escherichia coli 2.30.30.60 57 12 79 1.88 2.36
1igqB00 82.61 Escherichia coliTranscriptional repressor protein korB 2.30.30.150 57 5 74 1.93 2.59
1jxmA01 82.32 Postsynaptic membraneRattus norvegicusProtein C-terminus bindingIonotropic glutamate receptor bindingDisks large homolog 4 2.30.30.40 80 18 67 2.31 3.42
1dj7B00 81.33 Ferredoxin-thioredoxin reductase, variable chainProtein bindingSynechocystis sp. PCC 6803 2.30.30.50 73 11 78 3.64 4.66
2aklA02 80.92 Phosphonate and phosphinate metabolismPseudomonas aeruginosaPhosphonoacetate hydrolase [EC:3.11.1.2]Putative uncharacterized protein 2.30.30.40 73 16 78 3.37 4.32
1i1jB00 80.65 Melanoma-derived growth regulatory proteinHomo sapiensExtracellular spaceCell proliferation 2.30.30.40 103 23 57 1.39 2.43
1biaA03 80.58 Biotin metabolismDNA bindingBirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]Bifunctional protein birABiotin-[acetyl-CoA-carboxylase] ligase activity 2.30.30.100 47 10 76 2.50 3.28
1jb0E00 80.40 Photosystem I subunit IVPhotosynthesisThermosynechococcus elongatus BP-1Photosystem I reaction center subunit IVMetabolic pathways 2.30.30.50 69 6 73 2.62 3.54
1udlA00 80.36 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 98 25 58 1.55 2.66
1ug1A00 80.30 Dynamin-binding proteinHomo sapiensProtein binding 2.30.30.40 92 23 61 1.68 2.71
1khcA01 80.22 Protein complex localizationRegulation of gene expression by genetic imprintingDNA (cytosine-5)-methyltransferase 3BChromosome, centromeric regionProtein binding 2.30.30.160 65 5 73 2.69 3.64
1ri9A00 79.88 FYN-binding proteinProtein phosphorylationNucleusHomo sapiensImmune response 2.30.30.40 77 10 72 2.37 3.26
1uffA00 79.69 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 93 27 61 1.73 2.82
1m9sA05 78.83 Internalin BListeria monocytogenesProtein bindingInternalin B 2.30.30.170 78 10 71 2.38 3.31
2o2oA00 78.67 NucleusHomo sapiensSH3 domain-containing kinase-binding protein 1 2.30.30.40 75 28 76 2.85 3.75
1ib8A02 78.56 Hypothetical proteinRibosome maturation factor rimPStreptococcus pneumoniae 2.30.30.180 67 10 77 2.78 3.58
2vv5A02 78.36 Escherichia coli O157:H7Small conductance mechanosensitive ion channel, MscS familySmall-conductance mechanosensitive channel 2.30.30.60 50 8 69 2.22 3.19
2k57A00 77.89 Pseudomonas syringae pv. phaseolicola 1448ALipoprotein, putative 2.30.30.100 55 7 74 2.90 3.89
1uebA02 77.55 Thermus thermophilus HB8Elongation factor EF-PElongation factor P 2.40.50.140 63 11 61 2.80 4.52
1awjA00 77.49 Mus musculusTyrosine-protein kinase ITK/TSKProtein binding 2.30.30.40 77 16 75 2.72 3.61
1m9sA04 77.31 Internalin BListeria monocytogenesProtein bindingInternalin B 2.30.30.170 86 13 67 2.67 3.96
1vytA01 77.21 Cardiac muscle contractionRattus norvegicusDilated cardiomyopathyVoltage-gated calcium channel complexCalcium channel, voltage-dependent, beta 3 subunit 2.30.30.40 108 8 54 1.71 3.13
1kq1H00 77.14 RNA degradationHost factor-I proteinSimilar to host factor-1Staphylococcus aureus subsp. aureus Mu50 2.30.30.100 66 5 68 2.85 4.18
3be3A00 76.54 Bordetella bronchisepticaPutative uncharacterized protein 2.30.30.320 75 6 60 2.84 4.73
1u1sA00 76.51 RNA degradationPseudomonas aeruginosaHost factor-I proteinProtein hfq 2.30.30.100 66 6 68 2.62 3.84
2hqxA01 76.42 Staphylococcal nuclease domain-containing protein 1NucleusGolgi apparatusTranscription cofactor activityHomo sapiens 2.30.30.140 81 6 60 2.35 3.88
1irxA02 76.06 Aminoacyl-tRNA biosynthesisLysyl-tRNA synthetase, class I [EC:6.1.1.6]Pyrococcus horikoshiiLysyl-tRNA synthetase 2.30.30.300 43 11 72 3.40 4.67
2fmmD00 75.44 SpindleChromobox protein 1Chromosome, centromeric regionChromatin bindingEnzyme binding 2.40.50.40 66 10 65 2.97 4.56
1d3bC00 74.51 SpliceosomeSystemic lupus erythematosusSmall nuclear ribonucleoprotein Sm D3Small nuclear ribonucleoprotein D3Spliceosomal complex 2.30.30.100 71 6 69 3.07 4.45
1m5q101 74.37 Pyrobaculum aerophilumSmall nuclear ribonucleoprotein homolog (Sm-like) 2.30.30.100 67 11 73 3.45 4.72
1pm3A00 73.88 Methanothermobacter thermautotrophicus str. Delta HPutative uncharacterized protein 2.30.30.240 69 15 62 2.53 4.06
2f1lA02 72.50 Pseudomonas aeruginosaRibosome maturation factor rimM16S rRNA processing protein RimM 2.30.30.240 72 11 61 2.82 4.61
1tovA00 71.28 Caenorhabditis elegansTubulin-specific chaperone B 2.30.30.190 97 11 50 2.50 4.95
1ub4B00 71.03 Escherichia coli O157:H7PemK-like protein 1 2.30.30.110 100 3 45 2.11 4.69
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Displaying entries 1 to 65 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1yn8A00
GQRAVALYDFEPENDNELRLAEGDIVFISYKHGQGWLVAENESGSKTGLVPEEFVSYIQ
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1yn8A00
GQRAVALYDFEPENDNELRLAEGDIVFISYKHGQGWLVAENESGSKTGLVPEEFVSYIQ
BLAST against CATH

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Domain History Events (11)

Domain assigned by auto on 15 Aug 2007 03:27

Assigning to "2.30.30.40" based on similarity with "1yn8B00"

Flow stage update by auto on 15 Aug 2007 03:17

No in_process hits for Domain "1yn8A00" ready to be processed

Update comment by auto on 15 Aug 2007 02:35

Domain "1yn8A00" hits Domain "1yn8C00" (100% over 100%) which is currently in process

Update comment by auto on 15 Aug 2007 01:27

Domain "1yn8A00" hits Domain "1yn8F00" (100% over 100%) which is currently in process

Update comment by auto on 14 Aug 2007 23:59

Domain "1yn8A00" hits Domain "1yn8B00" (100% over 100%) which is currently in process

Update comment by auto on 14 Aug 2007 22:47

Domain "1yn8A00" hits Domain "1yn8E00" (100% over 100%) which is currently in process

Flow stage update by auto on 20 Jul 2007 10:57

Domain "1yn8A00" hits Domain "1yn8D00" (100% over 100%) which is currently in process

Flow stage update by auto on 20 Jul 2007 10:57

NW result present for Domain "1yn8A00"

Flow stage update by auto on 16 Jul 2007 22:37

All required files are present for Domain "1yn8A00"

Flow stage update by auto on 14 Jul 2007 06:01

Beginning processing for Domain "1yn8A00"

Insertion by auto on 14 Jul 2007 04:25

Final ChopClose added based on similarity with "1yn8B"