CATH Classification

Domain Context

CATH Clusters

Superfamily Carbonic anhydrase
Functional Family Beta-carbonic anhydrase 1

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P9WPJ7
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P9WPJ7
MTCA1_MYCTU
Mycobacterium tuberculosis H37Rv
Beta-carbonic anhydrase 1

PDB Structure

PDB 1YLK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and function of carbonic anhydrases from Mycobacterium tuberculosis.
Suarez Covarrubias, A., Larsson, A.M., Hogbom, M., Lindberg, J., Bergfors, T., Bjorkelid, C., Mowbray, S.L., Unge, T., Jones, T.A.
J.Biol.Chem.