CATH Domain: 1y0mA00 XML data for domain: 1y0mA00

Molscript image for 1y0mA00
1y0mA00
PDB coordinates for domain 1y0mA00

PDB 1y0m, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.30 SH3 type barrels.
2.30.30.40 SH3 Domains Gene3D
2.30.30.40.5
2.30.30.40.5.1
2.30.30.40.5.1.1
2.30.30.40.5.1.1.1
2.30.30.40.5.1.1.1.1

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Segment boundaries for domain 1y0mA00

Chopping figure for domain 1y0mA00
DomainStart PDB ResidueStop PDB Residue
1y0mA00 791 851

Structural Neighbourhood (67 entries)

There are 67 matching structural neighberhood comparisons for CATH ID 2.30.30.40.5.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 67 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2j6fA00 93.48 CD2-associated proteinRufflePlasma membraneSH3 domain bindingStructural constituent of cytoskeleton 2.30.30.40 57 36 93 1.13 1.21
2ak5B00 93.45 Rattus norvegicusFocal adhesionProtein bindingGrowth coneCytoplasm 2.30.30.40 64 40 93 1.38 1.47
1jo8A00 93.22 Actin cortical patch assemblyMating projection tipActin-binding proteinEstablishment of cell polarityProtein localization 2.30.30.40 58 37 93 1.53 1.64
1w70A00 92.68 Protein dimerization activityLeukocyte transendothelial migrationNeutrophil cytosolic factor 4CytosolNADPH oxidase complex 2.30.30.40 60 23 98 1.94 1.97
3i35A00 92.39 Focal adhesionHomo sapiensLIM and SH3 domain protein 1SH3/SH2 adaptor activity 2.30.30.40 56 35 91 1.26 1.37
2vwfA00 92.18 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 56 35 93 1.35 1.45
1sshA00 92.11 Cellular bud neckIdentical protein bindingActin cortical patch localizationSaccharomyces cerevisiaeMitochondrion 2.30.30.40 60 30 96 2.49 2.58
1zlmA00 91.87 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 58 32 96 1.91 1.98
3i9qA00 91.36 Spectrin alpha chain, brainGallus gallusSpectrin alpha 2.30.30.40 57 28 95 1.27 1.34
1ov3A02 91.22 GTP bindingSoluble fractionSH3 domain bindingCellular defense responseSuperoxide anion generation 2.30.30.40 54 24 90 1.29 1.43
1ckaA00 90.89 Pathways in cancerChemokine signaling pathwayNeurotrophin signaling pathwayFc gamma R-mediated phagocytosisErbB signaling pathway 2.30.30.40 56 32 91 1.64 1.79
2v1qA00 90.86 Actin cortical patch assemblyMating projection tipIdentical protein bindingNucleusActin filament organization 2.30.30.40 60 20 95 1.54 1.62
2jteA00 90.78 Mus musculusCD2-associated protein 2.30.30.40 64 36 92 1.89 2.05
2rqtA00 89.94 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing proteinArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1Fc gamma R-mediated phagocytosisHomo sapiensProtein binding 2.30.30.40 61 28 95 1.80 1.89
1jegA00 89.57 Tyrosine-protein kinase CSKProtein bindingCell-cell junctionMus musculusATP binding 2.30.30.40 60 18 96 2.04 2.11
3h0hA00 89.48 T cell receptor signaling pathwayLearningPrion diseasesFeeding behaviorTyrosine-protein kinase Fyn 2.30.30.40 63 35 93 2.29 2.45
1yn8A00 89.42 NucleusHyperosmotic responseResponse to heatNegative regulation of protein kinase activityProtein binding 2.30.30.40 59 20 95 1.85 1.95
3ehrB01 89.39 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 62 25 93 2.33 2.49
1zuyA00 89.35 Identical protein bindingMating projection tipReceptor-mediated endocytosisActin cortical patch localizationResponse to salt stress 2.30.30.40 58 22 91 1.73 1.89
1ad5A01 89.25 Protein phosphorylationTyrosine-protein kinase HCKHomo sapiensMesoderm developmentProtein binding 2.30.30.40 63 33 90 1.92 2.12
3eg3A00 89.23 DNA damage response, signal transduction resulting in induction of apoptosisProto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2]Pathways in cancerNucleolusNeurotrophin signaling pathway 2.30.30.40 62 23 95 2.03 2.13
1x6bA01 89.20 Rho guanine nucleotide exchange factor 16Homo sapiens 2.30.30.40 64 21 90 1.49 1.64
2v1rA00 88.95 PeroxisomePeroxin-13Protein binding, bridgingPeroxisomal membrane protein PAS20Peroxisomal membrane 2.30.30.40 67 25 86 1.33 1.54
1griA01 88.71 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 48 33 80 1.17 1.46
1ycsB02 88.29 Induction of apoptosisNF-kappaB bindingNegative regulation of cell cycleHomo sapiensApoptosis-stimulating of p53 protein 2 2.30.30.40 64 25 90 2.27 2.50
2vknA00 88.16 MAPK signaling pathway - yeastIdentical protein bindingMating projection tipPseudohyphal growthOsmosensor activity 2.30.30.40 66 30 89 2.12 2.37
1ng2A02 88.12 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 68 21 83 2.16 2.58
1j3tA00 88.01 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 74 33 78 1.32 1.68
2csqA01 87.86 RIMS-binding protein 2Homo sapiens 2.30.30.40 65 30 86 1.64 1.90
1wx6A01 87.77 NCK adaptor proteinPositive regulation of T cell proliferationRegulation of epidermal growth factor receptor activityT cell receptor signaling pathwayEpidermal growth factor receptor signaling pathway 2.30.30.40 66 26 90 2.30 2.53
2ablA01 87.56 DNA damage response, signal transduction resulting in induction of apoptosisProto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2]Pathways in cancerNucleolusNeurotrophin signaling pathway 2.30.30.40 66 23 90 2.05 2.25
1gcqC00 87.14 Integrin-mediated signaling pathwayProto-oncogene vavProtein bindingMus musculusT cell differentiation 2.30.30.40 69 18 85 2.29 2.68
1uhfA00 86.79 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 69 33 85 2.31 2.70
2js2A00 86.44 Receptor bindingNCK adaptor proteinPositive regulation of T cell proliferationT cell receptor signaling pathwayPositive regulation of actin filament polymerization 2.30.30.40 63 35 93 2.56 2.73
1spkA00 85.87 Mus musculusBrain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2.30.30.40 72 23 83 2.15 2.58
3i5rA00 85.67 ErbB-3 class receptor bindingInsulin-like growth factor receptor signaling pathwayInsulin receptor signaling pathwayGrowth hormone receptor signaling pathwayInsulin-like growth factor receptor binding 2.30.30.40 81 28 74 2.22 3.00
1awwA00 85.00 Phosphatidylinositol-3,4,5-trisphosphate bindingInduction of apoptosis by extracellular signalsIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.30.40 67 30 89 2.58 2.88
1ng2A01 84.88 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 44 22 73 1.85 2.52
2ke9A00 84.74 Caskin-2Homo sapiens 2.30.30.40 67 23 88 3.20 3.63
2epdA00 84.59 Rho protein signal transductionCytoskeleton organizationRho GTPase-activating protein 4Homo sapiensRho GTPase activator activity 2.30.30.40 76 23 78 2.07 2.62
1bb9A00 84.09 Rattus norvegicusProtein heterodimerization activityProtein C-terminus bindingSynaptic vesicle endocytosisMyc box-dependent-interacting protein 1 2.30.30.40 83 30 71 2.84 4.00
1u3oA01 83.24 Rattus norvegicusVesicle-mediated transportProtein bindingAxonogenesisNeuron projection 2.30.30.40 62 16 88 3.11 3.51
1tucA00 82.27 Spectrin alpha chain, brainGallus gallusSpectrin alpha 2.30.30.40 61 16 75 3.48 4.61
1jxmA01 81.28 Postsynaptic membraneRattus norvegicusProtein C-terminus bindingIonotropic glutamate receptor bindingDisks large homolog 4 2.30.30.40 80 21 68 2.92 4.25
2aklA02 81.10 Phosphonate and phosphinate metabolismPseudomonas aeruginosaPhosphonoacetate hydrolase [EC:3.11.1.2]Putative uncharacterized protein 2.30.30.40 73 15 80 3.47 4.29
1sf9A02 80.88 Bacillus subtilisUncharacterized protein yfhH 2.30.30.340 54 7 75 3.46 4.61
1uffA00 80.80 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 93 36 64 2.35 3.64
1i1jB00 80.56 Melanoma-derived growth regulatory proteinHomo sapiensExtracellular spaceCell proliferation 2.30.30.40 103 26 58 2.37 4.07
2heqA01 80.32 Bacillus subtilisSPBc2 prophage-derived uncharacterized protein yorP 2.30.30.40 54 7 83 3.13 3.76
2hbwA01 80.12 Anabaena variabilis ATCC 29413NLP/P60 2.30.30.40 72 8 79 3.43 4.33
1udlA00 80.11 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 98 40 61 2.37 3.87
1mhnA00 79.81 Survival motor neuron proteinSurvival motor neuron proteinHomo sapiensProtein binding 2.30.30.140 59 6 85 4.18 4.92
2o2oA00 79.69 NucleusHomo sapiensSH3 domain-containing kinase-binding protein 1 2.30.30.40 75 33 80 3.05 3.81
1ug1A00 79.68 Dynamin-binding proteinHomo sapiensProtein binding 2.30.30.40 92 11 65 2.35 3.60
2k57A00 79.31 Pseudomonas syringae pv. phaseolicola 1448ALipoprotein, putative 2.30.30.100 55 10 76 3.03 3.95
2g3rA01 78.38 CytoplasmHomo sapiensTumor suppressor p53-binding protein 1Protein binding 2.30.30.140 53 7 83 3.83 4.60
1jb0E00 77.94 Photosystem I subunit IVPhotosynthesisThermosynechococcus elongatus BP-1Photosystem I reaction center subunit IVMetabolic pathways 2.30.30.50 69 13 72 3.44 4.75
2rh2A00 77.79 Dihydrofolate reductase type 2Escherichia coli 2.30.30.60 57 8 76 3.71 4.84
1ri9A00 77.31 FYN-binding proteinProtein phosphorylationNucleusHomo sapiensImmune response 2.30.30.40 77 11 74 3.02 4.08
1awjA00 76.48 Mus musculusTyrosine-protein kinase ITK/TSKProtein binding 2.30.30.40 77 25 76 3.03 3.95
1ib8A02 76.22 Hypothetical proteinRibosome maturation factor rimPStreptococcus pneumoniae 2.30.30.180 67 10 76 3.19 4.19
1vytA01 76.13 Cardiac muscle contractionRattus norvegicusDilated cardiomyopathyVoltage-gated calcium channel complexCalcium channel, voltage-dependent, beta 3 subunit 2.30.30.40 108 20 54 2.55 4.67
1u1sA00 75.91 RNA degradationPseudomonas aeruginosaHost factor-I proteinProtein hfq 2.30.30.100 66 1 68 3.32 4.87
1biaA03 75.71 Biotin metabolismDNA bindingBirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]Bifunctional protein birABiotin-[acetyl-CoA-carboxylase] ligase activity 2.30.30.100 47 10 78 3.83 4.89
3by7E00 74.89 2.30.30.100 74 6 58 2.25 3.87
1d3bC00 73.77 SpliceosomeSystemic lupus erythematosusSmall nuclear ribonucleoprotein Sm D3Small nuclear ribonucleoprotein D3Spliceosomal complex 2.30.30.100 71 6 64 3.00 4.63
1d3bB00 71.64 Small nuclear ribonucleoprotein-associated proteins B and B'Spliceosomal complexU7 snRNPHomo sapiensProtein binding 2.30.30.100 81 5 56 2.81 4.95
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Displaying entries 1 to 67 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1y0mA00
TFKSAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMIN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1y0mA00
TFKSAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMIN
BLAST against CATH

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Domain History Events (5)

Domain assigned by auto on 28 Apr 2006 20:22

Assigning to "2.30.30.40" based on similarity with "1hsq000" (NWSI: 93.4426229508197, NWO: 85.9154929577465, SPS: 86.48, SPO: 84, RMSD: 2.66)

Flow stage update by auto on 28 Apr 2006 17:50

NW result present for Domain "1y0mA00"

Flow stage update by auto on 28 Apr 2006 17:46

All required files are present for Domain "1y0mA00"

Flow stage update by auto on 27 Apr 2006 17:32

Beginning processing for Domain "1y0mA00"

Insertion by auto on 17 Mar 2006 18:28

Final ChopClose added based on similarity with "1ywoA" [LEE: 3, LME: 0, MR: 0, LG: 3, SS: 95.22, SI: 100, SO: 95.3125]