CATH Domain: 1xgkA01 XML data for domain: 1xgkA01

Molscript image for 1xgkA01
1xgkA01
PDB coordinates for domain 1xgkA01

PDB 1xgk, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.720 NAD(P)-binding Rossmann-like Domain Gene3D
3.40.50.720.5
3.40.50.720.5.1
3.40.50.720.5.1.1
3.40.50.720.5.1.1.1
3.40.50.720.5.1.1.1.1

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Segment boundaries for domain 1xgkA01

Chopping figure for domain 1xgkA01
DomainStart PDB ResidueStop PDB Residue
1xgkA01 3 151
1xgkA01 191 219
1xgkA01 275 328
1xgkA02 152 190
1xgkA02 220 274
1xgkA02 329 351

Structural Neighbourhood (42 entries)

There are 42 matching structural neighberhood comparisons for CATH ID 3.40.50.720.5.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 42 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2a35A00 82.59 Pseudomonas aeruginosaPutative uncharacterized protein 3.40.50.720 208 15 81 2.86 3.52
1r6dA01 82.18 DTDP-glucose 4,6-dehydrataseStreptomyces venezuelae 3.40.50.720 218 12 83 3.33 4.01
2gasA01 82.05 Medicago sativaIsoflavone reductase 3.40.50.720 188 17 85 3.60 4.23
3e8xA00 81.78 BH1520 proteinBacillus halodurans 3.40.50.720 204 14 81 3.31 4.05
2a4kB01 81.62 3.40.50.720 196 12 76 2.69 3.52
1ek6A02 81.27 Amino sugar and nucleotide sugar metabolismGalactose metabolismUDP-glucose 4-epimeraseProtein homodimerization activityUDP-glucose 4-epimerase activity 3.40.50.720 218 11 79 3.36 4.23
1eq2A01 80.82 Metabolic pathwaysLipopolysaccharide biosynthesisMembraneProtein bindingADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] 3.40.50.720 202 13 85 3.65 4.29
1n7hA02 80.75 Amino sugar and nucleotide sugar metabolismGDPmannose 4,6-dehydratase [EC:4.2.1.47]Fructose and mannose metabolismCytosolMetabolic pathways 3.40.50.720 231 12 80 3.39 4.19
1vl0B01 80.54 DTDP-4-dehydrorhamnose reductase, rfbD orthologDTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesis 3.40.50.720 200 13 78 3.37 4.28
1e6uA01 80.31 Amino sugar and nucleotide sugar metabolismFructose and mannose metabolismMetabolic pathwaysGDP-L-fucose synthaseGDP-L-fucose synthase [EC:1.1.1.271] 3.40.50.720 220 11 77 3.02 3.89
1xq6A00 80.30 Arabidopsis thalianaResponse to abscisic acid stimulusUncharacterized protein At5g02240Plasma membraneApoplast 3.40.50.720 253 17 71 3.49 4.91
1uzmB00 80.19 Beta-ketoacyl ACP reductase [EC:1.1.1.100]3-oxoacyl-[acyl-carrier-protein] reductaseMycobacterium tuberculosis 3.40.50.720 210 11 78 3.19 4.06
1i24A01 80.17 Amino sugar and nucleotide sugar metabolismZinc ion bindingGlycolipid biosynthetic processChloroplastSulfotransferase activity 3.40.50.720 235 8 72 3.13 4.30
1kbzA01 79.99 Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesisDTDP-4-dehydrorhamnose reductaseSalmonella enterica subsp. enterica serovar Typhimurium 3.40.50.720 213 13 80 3.44 4.28
3gemD00 79.80 Pseudomonas syringae pv. phaseolicola 1448A[EC:1.-.-.-]Oxidoreductase, short chain dehydrogenase/reductase family 3.40.50.720 209 10 84 3.23 3.84
2bllA01 79.75 Amino sugar and nucleotide sugar metabolismOxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorHydroxymethyl-, formyl- and related transferase activityUDP-GlcUA decarboxylase/UDP-L-Ara4N formyltransferase [EC:1.1.1.- 2.1.2.-]Bifunctional polymyxin resistance protein ArnA 3.40.50.720 243 11 77 3.70 4.76
2qq5A00 79.62 NucleusGolgi apparatusEndoplasmic reticulumHomo sapiensDehydrogenase/reductase SDR family member 1 3.40.50.720 238 10 74 2.65 3.56
3grpD00 79.43 3-oxoacyl-(Acyl carrierprotein) reductaseBartonella henselae3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Fatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 209 13 81 3.10 3.79
2hrzA01 79.39 Agrobacterium tumefaciens str. C58Nucleoside-diphosphate-sugar epimerase 3.40.50.720 224 11 80 3.93 4.86
2z1nA00 79.36 Aeropyrum pernix3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Putative dehydrogenaseFatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 237 13 75 3.12 4.15
1xq1A00 78.83 Arabidopsis thalianaTropinone reductase homolog At1g07440Response to cadmium ion 3.40.50.720 218 12 77 2.82 3.66
3d7lA00 78.77 Listeria innocuaLin1944 protein 3.40.50.720 196 8 74 3.31 4.45
1gz6B01 78.72 PeroxisomeRattus norvegicusPrimary bile acid biosynthesis3(or 17)beta-hydroxysteroid dehydrogenase activityPeroxisomal multifunctional enzyme type 2 3.40.50.720 219 10 80 3.69 4.59
1zk4A00 78.33 Lactobacillus brevisR-specific alcohol dehydrogenase 3.40.50.720 244 10 73 3.19 4.35
2ztuB00 78.32 Pseudomonas fragiD(-)-3-hydroxybutyrate dehydrogenase 3.40.50.720 207 9 77 3.23 4.18
1spxA00 78.31 Caenorhabditis elegansProtein D1054.8, confirmed by transcript evidenceDetermination of adult lifespan 3.40.50.720 237 11 75 3.23 4.25
1xg5B00 77.83 Dehydrogenase/reductase SDR family member 11Homo sapiens 3.40.50.720 241 15 72 3.33 4.59
2ag5C00 77.65 NAD or NADH bindingMetabolic pathwaysButanoate metabolismCytoplasm3-hydroxybutyrate dehydrogenase type 2 3.40.50.720 244 11 73 3.25 4.41
1ja9A00 77.55 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Fatty acid biosynthesis1,3,6,8-tetrahydroxynaphthalene reductaseBiosynthesis of unsaturated fatty acidsMagnaporthe grisea 3.40.50.720 259 15 69 3.21 4.64
1zemA00 77.53 Gluconobacter oxydansXylitol dehydrogenase 3.40.50.720 260 9 68 3.21 4.72
1cydA00 77.53 Carbonyl reductase (NADPH) activityArachidonic acid metabolismProtein tetramerizationCarbonyl reductase [NADPH] 2Metabolic pathways 3.40.50.720 242 12 74 3.45 4.64
2axqA01 77.52 Lysine biosynthetic process via aminoadipic acidIdentical protein bindingSaccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10]Saccharopine dehydrogenase [NADP+, L-glutamate-forming]Metabolic pathways 3.40.50.720 174 13 77 3.70 4.79
2ew8B00 77.31 Ethylbenzene degradation(S)-1-Phenylethanol dehydrogenaseAromatoleum aromaticum EbN1 3.40.50.720 228 11 77 3.36 4.35
2zatA00 77.10 PeroxisomeDehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]Sus scrofaDehydrogenase/reductase SDR family member 4Retinol metabolism 3.40.50.720 251 11 72 3.38 4.69
2rhcA00 76.95 Putative ketoacyl reductaseBiosynthesis of type II polyketide backboneStreptomyces coelicolorKetoacyl reductase [EC:1.3.1.-] 3.40.50.720 257 13 70 3.28 4.66
3iccA00 76.45 Bacillus anthracisOxidoreductase, short-chain dehydrogenase/reductase family 3.40.50.720 248 12 72 3.41 4.72
3f1lB00 76.21 Uncharacterized oxidoreductase yciKEscherichia coli K-12 3.40.50.720 244 14 71 3.00 4.18
1y7tA01 75.90 Citrate cycle (TCA cycle)Pyruvate metabolismGlyoxylate and dicarboxylate metabolismMetabolic pathwaysMalate dehydrogenase [EC:1.1.1.37] 3.40.50.720 153 13 58 2.92 5.00
2ekpA00 75.39 Pentose and glucuronate interconversionsThermus thermophilus HB82-deoxy-D-gluconate 3-dehydrogenase2-deoxy-D-gluconate 3-dehydrogenase [EC:1.1.1.125] 3.40.50.720 238 12 73 3.50 4.76
2aefA01 74.56 Methanothermobacter thermautotrophicus str. Delta HCalcium-gated potassium channel mthK 3.40.50.720 115 7 55 2.70 4.90
1p3dA01 71.28 D-Glutamine and D-glutamate metabolismUDP-N-acetylmuramate--L-alanine ligaseUDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]Haemophilus influenzaePeptidoglycan biosynthesis 3.40.50.720 87 13 42 2.03 4.83
1q0qA01 70.83 Terpenoid backbone biosynthesisMetabolic pathways1-deoxy-D-xylulose 5-phosphate reductoisomerase1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]1-deoxy-D-xylulose-5-phosphate reductoisomerase activity 3.40.50.720 150 12 56 2.74 4.85
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Displaying entries 1 to 42 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1xgkA01
QQKKTIAVVGATGRQGASLIRVAAAVGHHVRAQVHSLKGLIAEELQAIPNVTLFQGPLLNNVPLMDTLFEGAHLAFINTT
SQAGDEIAIGKDLADAAKRAGTIQHYIYSSMPDHSLYGPWPAVPMWAPKFTVENYVRQLGLPSTFVYAGDAEHDVGPALL
QIFKDGPQKWNGHRIALTPYFPLPEFSPGGVISQRVTDEARKLWSGW
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1xgkA01
MAQQKKTIAVVGATGRQGASLIRVAAAVGHHVRAQVHSLKGLIAEELQAIPNVTLFQGPLLNNVPLMDTLFEGAHLAFIN
TTSQAGDEIAIGKDLADAAKRAGTIQHYIYSSMPDHSLYGPWPAVPMWAPKFTVENYVRQLGLPSTFVYAGDAEHDVGPA
LLQIFKDGPQKWNGHRIALTPYFPLPEFSRPAAGSPKGLGPANGKGAGAGMMQGPGGVISQRVTDEARKLWSGW
BLAST against CATH

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Domain History Events (5)

Domain assigned by auto on 28 Apr 2006 19:58

Assigning to "3.40.50.720" based on similarity with "1ti7A01" (NWSI: 99.1452991452991, NWO: 100, SPS: 98.23, SPO: 99, RMSD: 0.40)

Flow stage update by auto on 28 Apr 2006 17:50

NW result present for Domain "1xgkA01"

Flow stage update by auto on 28 Apr 2006 17:46

All required files are present for Domain "1xgkA01"

Flow stage update by auto on 27 Apr 2006 17:31

Beginning processing for Domain "1xgkA01"

Insertion by auto on 09 Mar 2006 17:25

Final ChopClose added based on similarity with "1k6jA" [LEE: 1, LME: 0, MR: 0, LG: 2, SS: 96.41, SI: 99.4318181818182, SO: 100]